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The map label for this gene is gluP [H]

Identifier: 51893006

GI number: 51893006

Start: 2007710

End: 2008906

Strand: Reverse

Name: gluP [H]

Synonym: STH1868

Alternate gene names: 51893006

Gene position: 2008906-2007710 (Counterclockwise)

Preceding gene: 51893007

Following gene: 51893005

Centisome position: 56.33

GC content: 71.51

Gene sequence:

>1197_bases
GTGAACTACTCGGCATATGTGGAATCGGTCGGCAGCCAGCTGGCGGACAGGGGCTTCGAGGTGCAGGCCGTGCCGCCGGA
GCTGCAGGGACGTCTGGCGCTGCTGGTCTCCCGGCAGGAGGAGTGGGGGAGGCTGCTGCTCGCGCTGGCCGCAGAGCTGA
ACCCGAGCGACCCGCAGGAGCGGGAGTCCCTGGCCCAAGCCTGCGGGGCGTGGGTGCGGGAGGCGCGCGGCGACGAGGTC
TGGCACATGATCCTGCTGTTCCCCTTCGACCGTACGGTGGGCGAGGAGGAGGCGGAGGCGATCGCCGCGCTGGAGGAGCG
GGACCCCGGGGAACGGTGGGGCGTGATCCCCTGGTCGGCGGATCTGGCGGTGGGGCTGCTGGACCAGCACACCGGGTTCC
CTCCGGTGGATGAGGCCGTGGCCCGCATCCTCACCGATGTGCCCGAGACGCCCGAGCGGCGGTTCGTGGAGGTCCGCCCG
CGGTACGAGGCCCGGCGCCCCTGGCCGGGGCTGGACCGGTTTCCCGCGACACGGCTGATCCTGGCCCTGACCGTGGCCTA
CTACCTCTGGACGGTGTGGATGGGCGGCGGGCTGCTGAACCTGATCAGCGGGCCGGACACCCTGTCCCTGGTGATCTGGG
GCGCGAACTACAGCCTGCTCACGCTGGCCGAGCGGACGCAGCAGTGGCGGCTGGTGAGCCACCTGTTCCTCCACGGCGGC
GCGATGCACCTGGCGTTCAACATGTGGGCCTTCTGGCAGGTGGGCCGTTACTGCGAGCTGATCTACGGCTCCGCGCGGAT
GCTGTTCATCTACTTCGTGGCCGGCGTGATCGGCGGGGTGGCCTCGGTCGCCGTGCGTCCCGGCCTGGTGATCAGCGTCG
GGGCGTCGGGCGCGATCCTGGGGCTGATGGGCGCGCTGATCTACTTCGCCACCACCGTCCGCAACCGGCGCGTCGACTGG
CAGGGGCTGCTGGCTCCGGTGGCCATCAACCTGCTATTCGGCTTCGTGTACGGGCGGGTGGACAACTACGCGCACATCGG
CGGCCTCCTGGGCGGACTGCTGGCGGCGTTCGTGGCCGGGGTTCCGGGCGAGCGCGGCGGCTGGCGGCAGTTGGCCGCCC
CGGCCCTGGGCGTGCTGGTCGGCCTGGTGGTGGCGGGCGTCCTGCCCCTGAAGCACGTGTCGACGCTGTTGCCGTAG

Upstream 100 bases:

>100_bases
TGCCGCCGGGGAAAGGTAAGCCCGTGGCAGGCGGTGAATTCGATAAGGACAGCTTTCCGGGCGATGGCGCTCGCGCCGTC
GGCCGTATCGGAGGTGGGCC

Downstream 100 bases:

>100_bases
GAGACGGACGGAGGCGCGCAGCGGTGTGAGTAAAGTTTTCGTGGGTACAACACATTTTTTCTCCTGAAATAGCAGGACGA
GAGATGTGCCCTTCCAAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNYSAYVESVGSQLADRGFEVQAVPPELQGRLALLVSRQEEWGRLLLALAAELNPSDPQERESLAQACGAWVREARGDEV
WHMILLFPFDRTVGEEEAEAIAALEERDPGERWGVIPWSADLAVGLLDQHTGFPPVDEAVARILTDVPETPERRFVEVRP
RYEARRPWPGLDRFPATRLILALTVAYYLWTVWMGGGLLNLISGPDTLSLVIWGANYSLLTLAERTQQWRLVSHLFLHGG
AMHLAFNMWAFWQVGRYCELIYGSARMLFIYFVAGVIGGVASVAVRPGLVISVGASGAILGLMGALIYFATTVRNRRVDW
QGLLAPVAINLLFGFVYGRVDNYAHIGGLLGGLLAAFVAGVPGERGGWRQLAAPALGVLVGLVVAGVLPLKHVSTLLP

Sequences:

>Translated_398_residues
MNYSAYVESVGSQLADRGFEVQAVPPELQGRLALLVSRQEEWGRLLLALAAELNPSDPQERESLAQACGAWVREARGDEV
WHMILLFPFDRTVGEEEAEAIAALEERDPGERWGVIPWSADLAVGLLDQHTGFPPVDEAVARILTDVPETPERRFVEVRP
RYEARRPWPGLDRFPATRLILALTVAYYLWTVWMGGGLLNLISGPDTLSLVIWGANYSLLTLAERTQQWRLVSHLFLHGG
AMHLAFNMWAFWQVGRYCELIYGSARMLFIYFVAGVIGGVASVAVRPGLVISVGASGAILGLMGALIYFATTVRNRRVDW
QGLLAPVAINLLFGFVYGRVDNYAHIGGLLGGLLAAFVAGVPGERGGWRQLAAPALGVLVGLVVAGVLPLKHVSTLLP
>Mature_398_residues
MNYSAYVESVGSQLADRGFEVQAVPPELQGRLALLVSRQEEWGRLLLALAAELNPSDPQERESLAQACGAWVREARGDEV
WHMILLFPFDRTVGEEEAEAIAALEERDPGERWGVIPWSADLAVGLLDQHTGFPPVDEAVARILTDVPETPERRFVEVRP
RYEARRPWPGLDRFPATRLILALTVAYYLWTVWMGGGLLNLISGPDTLSLVIWGANYSLLTLAERTQQWRLVSHLFLHGG
AMHLAFNMWAFWQVGRYCELIYGSARMLFIYFVAGVIGGVASVAVRPGLVISVGASGAILGLMGALIYFATTVRNRRVDW
QGLLAPVAINLLFGFVYGRVDNYAHIGGLLGGLLAAFVAGVPGERGGWRQLAAPALGVLVGLVVAGVLPLKHVSTLLP

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 43544; Mature: 43544

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSAYVESVGSQLADRGFEVQAVPPELQGRLALLVSRQEEWGRLLLALAAELNPSDPQE
CCHHHHHHHHHHHHHHCCCEEEECCHHHCCCEEHEEECHHHHHHHHHHHHHHCCCCCHHH
RESLAQACGAWVREARGDEVWHMILLFPFDRTVGEEEAEAIAALEERDPGERWGVIPWSA
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
DLAVGLLDQHTGFPPVDEAVARILTDVPETPERRFVEVRPRYEARRPWPGLDRFPATRLI
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
LALTVAYYLWTVWMGGGLLNLISGPDTLSLVIWGANYSLLTLAERTQQWRLVSHLFLHGG
HHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
AMHLAFNMWAFWQVGRYCELIYGSARMLFIYFVAGVIGGVASVAVRPGLVISVGASGAIL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHH
GLMGALIYFATTVRNRRVDWQGLLAPVAINLLFGFVYGRVDNYAHIGGLLGGLLAAFVAG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
VPGERGGWRQLAAPALGVLVGLVVAGVLPLKHVSTLLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYSAYVESVGSQLADRGFEVQAVPPELQGRLALLVSRQEEWGRLLLALAAELNPSDPQE
CCHHHHHHHHHHHHHHCCCEEEECCHHHCCCEEHEEECHHHHHHHHHHHHHHCCCCCHHH
RESLAQACGAWVREARGDEVWHMILLFPFDRTVGEEEAEAIAALEERDPGERWGVIPWSA
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
DLAVGLLDQHTGFPPVDEAVARILTDVPETPERRFVEVRPRYEARRPWPGLDRFPATRLI
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
LALTVAYYLWTVWMGGGLLNLISGPDTLSLVIWGANYSLLTLAERTQQWRLVSHLFLHGG
HHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
AMHLAFNMWAFWQVGRYCELIYGSARMLFIYFVAGVIGGVASVAVRPGLVISVGASGAIL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHH
GLMGALIYFATTVRNRRVDWQGLLAPVAINLLFGFVYGRVDNYAHIGGLLGGLLAAFVAG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
VPGERGGWRQLAAPALGVLVGLVVAGVLPLKHVSTLLP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]