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The map label for this gene is efp

Identifier: 51893002

GI number: 51893002

Start: 2003833

End: 2004390

Strand: Reverse

Name: efp

Synonym: STH1864

Alternate gene names: 51893002

Gene position: 2004390-2003833 (Counterclockwise)

Preceding gene: 51893003

Following gene: 51893001

Centisome position: 56.21

GC content: 62.37

Gene sequence:

>558_bases
GTGATTTCGGTTAACGATCTGCGGAACGGCATGACCATCGAAATGGACGGCACCGTCTACCAGGTGATCGAGTTCCTGCA
TGTGAAGCCCGGCAAGGGCGCCGCGTTTGTGCGGACCAAGCTGAAGAACATCCTGACGGGGGCGACCATCGAAACGACCT
TCCGCGCCGGCGAGAAGGTGGAGCAGGCGAACGTGGACCGCCGGGAGTATCAGTTCCTGTATGCGGACCAGGGCGTCTGG
GTCTTCATGAACAACGAGACCTTCGAGCAAATCGAGCTCACCGAGGAGCAGGTGGGCAACGCGCCCAACTTCCTGCTGGA
GAACATGACGGTGCAGATCGCCAGCTGGAAGGGCCAGGTCATCGGCGTGGACCTGCCCAACACGGTGGAGCTGAAGGTCG
TCGAGACGGAGCCTGGCTTCAAGGGCGACACCGCCACCGGCACCTACAAGCCCGCCAAGCTGGAGACCGGTTACGTCGTG
CAGGTGCCGCTCTTCGTCAACACCGGCGACGTCATCAAGGTCGACACCCGGACGGGCGAGTATCTGTCCCGGGCCTGA

Upstream 100 bases:

>100_bases
CCACTCGCCGAAGGAGCTTCTCATTCTGTAGGATTGGTTTCTGTTCGCCCCCGGGGCGTAGAAATTCTGGCGTGAAGCGT
GGAGCGGAGGGGACTGTACA

Downstream 100 bases:

>100_bases
TCGCCATGCAATGAAAATCGGGGTGCGCAGCGCGCACCCCGATTTGTTTTCCGGTCAACCCGGGCAGACTATCGCGCGGG
ACTGCCCGAGGAAGGAGGAG

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISVNDLRNGMTIEMDGTVYQVIEFLHVKPGKGAAFVRTKLKNILTGATIETTFRAGEKVEQANVDRREYQFLYADQGVW
VFMNNETFEQIELTEEQVGNAPNFLLENMTVQIASWKGQVIGVDLPNTVELKVVETEPGFKGDTATGTYKPAKLETGYVV
QVPLFVNTGDVIKVDTRTGEYLSRA

Sequences:

>Translated_185_residues
MISVNDLRNGMTIEMDGTVYQVIEFLHVKPGKGAAFVRTKLKNILTGATIETTFRAGEKVEQANVDRREYQFLYADQGVW
VFMNNETFEQIELTEEQVGNAPNFLLENMTVQIASWKGQVIGVDLPNTVELKVVETEPGFKGDTATGTYKPAKLETGYVV
QVPLFVNTGDVIKVDTRTGEYLSRA
>Mature_185_residues
MISVNDLRNGMTIEMDGTVYQVIEFLHVKPGKGAAFVRTKLKNILTGATIETTFRAGEKVEQANVDRREYQFLYADQGVW
VFMNNETFEQIELTEEQVGNAPNFLLENMTVQIASWKGQVIGVDLPNTVELKVVETEPGFKGDTATGTYKPAKLETGYVV
QVPLFVNTGDVIKVDTRTGEYLSRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=50, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=31.7460317460317, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_SYMTH (Q67N94)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075693.1
- ProteinModelPortal:   Q67N94
- SMR:   Q67N94
- GeneID:   2979509
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH1864
- NMPDR:   fig|292459.1.peg.1798
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- BioCyc:   STHE292459:STH1864-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20645; Mature: 20645

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01275 EFP; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNDLRNGMTIEMDGTVYQVIEFLHVKPGKGAAFVRTKLKNILTGATIETTFRAGEKV
CCCHHHCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHH
EQANVDRREYQFLYADQGVWVFMNNETFEQIELTEEQVGNAPNFLLENMTVQIASWKGQV
HHCCCCCHHEEEEEECCCEEEEECCCCCEEEEECHHHCCCCCCEEEECEEEEEEECCCEE
IGVDLPNTVELKVVETEPGFKGDTATGTYKPAKLETGYVVQVPLFVNTGDVIKVDTRTGE
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCEEEEEEEEECCCCEEEEECCCCH
YLSRA
HHHCC
>Mature Secondary Structure
MISVNDLRNGMTIEMDGTVYQVIEFLHVKPGKGAAFVRTKLKNILTGATIETTFRAGEKV
CCCHHHCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHH
EQANVDRREYQFLYADQGVWVFMNNETFEQIELTEEQVGNAPNFLLENMTVQIASWKGQV
HHCCCCCHHEEEEEECCCEEEEECCCCCEEEEECHHHCCCCCCEEEECEEEEEEECCCEE
IGVDLPNTVELKVVETEPGFKGDTATGTYKPAKLETGYVVQVPLFVNTGDVIKVDTRTGE
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCEEEEEEEEECCCCEEEEECCCCH
YLSRA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA