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The map label for this gene is yqhT [H]

Identifier: 51893003

GI number: 51893003

Start: 2004460

End: 2005533

Strand: Reverse

Name: yqhT [H]

Synonym: STH1865

Alternate gene names: 51893003

Gene position: 2005533-2004460 (Counterclockwise)

Preceding gene: 51893004

Following gene: 51893002

Centisome position: 56.24

GC content: 67.13

Gene sequence:

>1074_bases
ATGTCCCAAGCGCGCCTGGCGCGCCTCAGGGCGCGACTCGAAGAACGGGGTCTCGACGCCGTTCTGATCGCCAAGCCCCA
CAACCGGGCCTACCTCAGCGGCTTCACCGGCAGCGCCGGCCTGCTGCTGATCACGGCCGACCGGGCGGCCCTGGTCACCG
ACTTCCGCTACGTCGAACAGGCGGCGGCGCAGGCCCCGGAGTTCGAGGTGATCAAGGCGGAGAGCGCCAACCAGGCGGTC
CTGACCCGGTTGGTAGAGGAGTGGGGCGTGAAGCGGATCGGCTTCGAGGGCGATTTCCTTACGGTGGACGAACACCAGAC
TTACCAGCAGTTTCTGGCCGGGTGCCAGTGGACCTCGGTTTCCGGGCTGGTCGAAGAGCTGCGCATGATCAAGGACGAGA
CGGAGATCGCCCTGATGCGCCGGGCGGCCGAGATCGCCGACGAGGCCTTCGCCCAGATCCTGCCGCTCATCAAGCCCGGC
GTTATCGAGCGGGATCTGGCCACGGAACTGGAGTACCGCATGAAGAAGCTGGGAGCGGAGGGTGTGGCGTTTGAGACCAT
CGTCGCCTCCGGCGCCCGCTCTTCCCTGCCCCACGGCGTGGCCAGCGACAAGGCGATCGAGGTCGGCGACCTGATCACCT
TCGACTTCGGCGCCGTGTACCAGGGCTACTGTTCCGACATGACCCGCACCGTCATGCTTGGGGAACCTACGGACAAGCAG
CGGGAGATCTACGGCATCGTGCTGGAGGCACAGAAGCGGGGTGTGGCGGCCTGCCGCCCCGGCATCACCGGCAGGGAGCT
GGACGACGTCTGCCGGTCGTACATCGCCGAGAAGGGCTACCGCGAATACTTCGGTCACGGCACGGGACACGGCGTCGGGC
GGTACATCCACGAGGGGCCGCGGGTCAGCCAGCGGGGCGGTGACGTGGTGCTCCGTCCCGGCATGGTGGTCACGGTGGAG
CCGGGCATCTACCTGCCAGGCTGGGGTGGCGTCCGGATCGAGGACATGCTGCTGGTCACCGAGTCGGGGGCTGAGTCGTT
CACCCACTCGCCGAAGGAGCTTCTCATTCTGTAG

Upstream 100 bases:

>100_bases
AGGCACCATCGCAGGGTTCGGAGCCGAGTCATACCGTCTCGGGCTGCGGGCCCTCGCGCACCTGCTGCAGGGCGACCGCG
CACAAAGGAGGAACTGACGC

Downstream 100 bases:

>100_bases
GATTGGTTTCTGTTCGCCCCCGGGGCGTAGAAATTCTGGCGTGAAGCGTGGAGCGGAGGGGACTGTACAGTGATTTCGGT
TAACGATCTGCGGAACGGCA

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSQARLARLRARLEERGLDAVLIAKPHNRAYLSGFTGSAGLLLITADRAALVTDFRYVEQAAAQAPEFEVIKAESANQAV
LTRLVEEWGVKRIGFEGDFLTVDEHQTYQQFLAGCQWTSVSGLVEELRMIKDETEIALMRRAAEIADEAFAQILPLIKPG
VIERDLATELEYRMKKLGAEGVAFETIVASGARSSLPHGVASDKAIEVGDLITFDFGAVYQGYCSDMTRTVMLGEPTDKQ
REIYGIVLEAQKRGVAACRPGITGRELDDVCRSYIAEKGYREYFGHGTGHGVGRYIHEGPRVSQRGGDVVLRPGMVVTVE
PGIYLPGWGGVRIEDMLLVTESGAESFTHSPKELLIL

Sequences:

>Translated_357_residues
MSQARLARLRARLEERGLDAVLIAKPHNRAYLSGFTGSAGLLLITADRAALVTDFRYVEQAAAQAPEFEVIKAESANQAV
LTRLVEEWGVKRIGFEGDFLTVDEHQTYQQFLAGCQWTSVSGLVEELRMIKDETEIALMRRAAEIADEAFAQILPLIKPG
VIERDLATELEYRMKKLGAEGVAFETIVASGARSSLPHGVASDKAIEVGDLITFDFGAVYQGYCSDMTRTVMLGEPTDKQ
REIYGIVLEAQKRGVAACRPGITGRELDDVCRSYIAEKGYREYFGHGTGHGVGRYIHEGPRVSQRGGDVVLRPGMVVTVE
PGIYLPGWGGVRIEDMLLVTESGAESFTHSPKELLIL
>Mature_356_residues
SQARLARLRARLEERGLDAVLIAKPHNRAYLSGFTGSAGLLLITADRAALVTDFRYVEQAAAQAPEFEVIKAESANQAVL
TRLVEEWGVKRIGFEGDFLTVDEHQTYQQFLAGCQWTSVSGLVEELRMIKDETEIALMRRAAEIADEAFAQILPLIKPGV
IERDLATELEYRMKKLGAEGVAFETIVASGARSSLPHGVASDKAIEVGDLITFDFGAVYQGYCSDMTRTVMLGEPTDKQR
EIYGIVLEAQKRGVAACRPGITGRELDDVCRSYIAEKGYREYFGHGTGHGVGRYIHEGPRVSQRGGDVVLRPGMVVTVEP
GIYLPGWGGVRIEDMLLVTESGAESFTHSPKELLIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=285, Percent_Identity=31.9298245614035, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI264681563, Length=226, Percent_Identity=32.3008849557522, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI260593665, Length=291, Percent_Identity=27.8350515463918, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI149589008, Length=291, Percent_Identity=27.8350515463918, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI93141226, Length=229, Percent_Identity=30.5676855895196, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI164420681, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI264681565, Length=223, Percent_Identity=31.390134529148, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40385867, Length=255, Percent_Identity=23.1372549019608, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788728, Length=358, Percent_Identity=42.1787709497207, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1789275, Length=280, Percent_Identity=33.2142857142857, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508215, Length=290, Percent_Identity=27.2413793103448, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17509539, Length=250, Percent_Identity=30, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71989583, Length=252, Percent_Identity=23.4126984126984, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71996291, Length=250, Percent_Identity=23.2, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=27.6679841897233, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=26.1484098939929, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=26.2096774193548, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322999, Length=244, Percent_Identity=28.6885245901639, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920384, Length=256, Percent_Identity=31.640625, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357079, Length=307, Percent_Identity=26.0586319218241, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21355531, Length=249, Percent_Identity=24.4979919678715, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17137632, Length=378, Percent_Identity=26.7195767195767, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161078230, Length=235, Percent_Identity=28.5106382978723, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357287, Length=235, Percent_Identity=28.5106382978723, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39194; Mature: 39063

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQARLARLRARLEERGLDAVLIAKPHNRAYLSGFTGSAGLLLITADRAALVTDFRYVEQ
CCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHH
AAAQAPEFEVIKAESANQAVLTRLVEEWGVKRIGFEGDFLTVDEHQTYQQFLAGCQWTSV
HHHCCCCEEEEECCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHHHHHHHCCCCCHH
SGLVEELRMIKDETEIALMRRAAEIADEAFAQILPLIKPGVIERDLATELEYRMKKLGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GVAFETIVASGARSSLPHGVASDKAIEVGDLITFDFGAVYQGYCSDMTRTVMLGEPTDKQ
CCCHHHHHHCCCHHCCCCCCCCCCCEEECCEEEECHHHHHHHHHHHHHEEEEECCCCCCC
REIYGIVLEAQKRGVAACRPGITGRELDDVCRSYIAEKGYREYFGHGTGHGVGRYIHEGP
CEEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCC
RVSQRGGDVVLRPGMVVTVEPGIYLPGWGGVRIEDMLLVTESGAESFTHSPKELLIL
CCCCCCCCEEECCCEEEEECCCEEECCCCCCEEEEEEEEECCCCHHHCCCCHHEEEC
>Mature Secondary Structure 
SQARLARLRARLEERGLDAVLIAKPHNRAYLSGFTGSAGLLLITADRAALVTDFRYVEQ
CHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHH
AAAQAPEFEVIKAESANQAVLTRLVEEWGVKRIGFEGDFLTVDEHQTYQQFLAGCQWTSV
HHHCCCCEEEEECCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHHHHHHHCCCCCHH
SGLVEELRMIKDETEIALMRRAAEIADEAFAQILPLIKPGVIERDLATELEYRMKKLGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GVAFETIVASGARSSLPHGVASDKAIEVGDLITFDFGAVYQGYCSDMTRTVMLGEPTDKQ
CCCHHHHHHCCCHHCCCCCCCCCCCEEECCEEEECHHHHHHHHHHHHHEEEEECCCCCCC
REIYGIVLEAQKRGVAACRPGITGRELDDVCRSYIAEKGYREYFGHGTGHGVGRYIHEGP
CEEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCC
RVSQRGGDVVLRPGMVVTVEPGIYLPGWGGVRIEDMLLVTESGAESFTHSPKELLIL
CCCCCCCCEEECCCEEEEECCCEEECCCCCCEEEEEEEEECCCCHHHCCCCHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]