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The map label for this gene is spo0A1 [H]

Identifier: 51892970

GI number: 51892970

Start: 1978453

End: 1979232

Strand: Reverse

Name: spo0A1 [H]

Synonym: STH1832

Alternate gene names: 51892970

Gene position: 1979232-1978453 (Counterclockwise)

Preceding gene: 51892971

Following gene: 51892969

Centisome position: 55.5

GC content: 70.64

Gene sequence:

>780_bases
ATGTCGGCCCACAAAGTTCGGCTCCTGGTGTGCGACGACAACCGCGACTTCTGCGCCCTGCTTCAGGAGTATTTCGCGCT
GCAGCCCGACATGGAGGTGGTGGGCGTGGCGCACAACGGCCTGGACGCGGTGGCGGCCATTCAGGAGCAGCAGCCGGACG
TGGTGTTGCTGGACATCATCATGCCTTACATGGACGGGATCGGCGTCCTGGAGCAACTGGCCCGGACGAAGCTGAGCGCC
CGGCCCAGGATCCTGATGCTGTCCGCGTTCGGCCAGGAGGCGATTGCCCGGCGGGTGATGGCCATGGGCGCGGACTACTA
CGTGGTCAAGCCGGTCGACTTGGAGATCCTCGCCGCGCGGGTTCGGCAGCTCGCGTGGGGTGATGCCCTCGCCGACTCGC
CGCGCGTTCCCCCGGCGTCGCACGCCGCCGGCCACACGCTGGACGAGGTGCATGCACTGCTGCGCGCCCTGGGCATCCCG
CCGCACCTGAAGGGATACCGGTACCTGGGCGACGCGATCCTGCTGGTTCTGGAGCAGCCCGAGCTCCTGGGCGCGGTGAC
CAAGGGGCTGTATCCCGCGGTCGCGCGCAGCCACGGAACCACCGCCTCCCGGGTCGAGCGGGCCATCCGCCACGCGGTCG
GCATGGCGTGGGACCGGGGGCTCGAGCCGCTGCGAAAGCTCTTCCGCCGCGGCGCGGAGGGCAGGCGGACCAAGCCCAGC
AACTCCGAGTTCATCGCCGCGGTGGTGGACCGGCTCCGGGCCGGCTCCGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
ACATCTATGTGTGTATACTTATAAACTATCGGTTCCCGGTTGCGCCTTTTGTGGGTGAGCGGCCCCGGGAACGTACGGTC
AGGTTGGGGGTTGAATGAGA

Downstream 100 bases:

>100_bases
GGCTCCGCGCACACGCTGCAGGGAATTGCGCTTCTTCAGCCGAAATGGTCTGCAAGAGAGTGCAGCAGGGGTGTGGCGGA
TGCTGAACGTGGTGATCGTC

Product: stage 0 sporulation protein A, two-component response regualtor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSAHKVRLLVCDDNRDFCALLQEYFALQPDMEVVGVAHNGLDAVAAIQEQQPDVVLLDIIMPYMDGIGVLEQLARTKLSA
RPRILMLSAFGQEAIARRVMAMGADYYVVKPVDLEILAARVRQLAWGDALADSPRVPPASHAAGHTLDEVHALLRALGIP
PHLKGYRYLGDAILLVLEQPELLGAVTKGLYPAVARSHGTTASRVERAIRHAVGMAWDRGLEPLRKLFRRGAEGRRTKPS
NSEFIAAVVDRLRAGSAAG

Sequences:

>Translated_259_residues
MSAHKVRLLVCDDNRDFCALLQEYFALQPDMEVVGVAHNGLDAVAAIQEQQPDVVLLDIIMPYMDGIGVLEQLARTKLSA
RPRILMLSAFGQEAIARRVMAMGADYYVVKPVDLEILAARVRQLAWGDALADSPRVPPASHAAGHTLDEVHALLRALGIP
PHLKGYRYLGDAILLVLEQPELLGAVTKGLYPAVARSHGTTASRVERAIRHAVGMAWDRGLEPLRKLFRRGAEGRRTKPS
NSEFIAAVVDRLRAGSAAG
>Mature_258_residues
SAHKVRLLVCDDNRDFCALLQEYFALQPDMEVVGVAHNGLDAVAAIQEQQPDVVLLDIIMPYMDGIGVLEQLARTKLSAR
PRILMLSAFGQEAIARRVMAMGADYYVVKPVDLEILAARVRQLAWGDALADSPRVPPASHAAGHTLDEVHALLRALGIPP
HLKGYRYLGDAILLVLEQPELLGAVTKGLYPAVARSHGTTASRVERAIRHAVGMAWDRGLEPLRKLFRRGAEGRRTKPSN
SEFIAAVVDRLRAGSAAG

Specific function: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the ex

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=149, Percent_Identity=34.2281879194631, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788192, Length=142, Percent_Identity=32.3943661971831, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082052, Length=125, Percent_Identity=34.4, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR014879
- InterPro:   IPR012052
- InterPro:   IPR011991
- ProDom:   PD010908 [H]

Pfam domain/function: PF00072 Response_reg; PF08769 Spo0A_C [H]

EC number: NA

Molecular weight: Translated: 28221; Mature: 28090

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHKVRLLVCDDNRDFCALLQEYFALQPDMEVVGVAHNGLDAVAAIQEQQPDVVLLDII
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCEEHHHHH
MPYMDGIGVLEQLARTKLSARPRILMLSAFGQEAIARRVMAMGADYYVVKPVDLEILAAR
HHHHCCHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHHHHHHCCCEEEECCCHHHHHHHH
VRQLAWGDALADSPRVPPASHAAGHTLDEVHALLRALGIPPHLKGYRYLGDAILLVLEQP
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
ELLGAVTKGLYPAVARSHGTTASRVERAIRHAVGMAWDRGLEPLRKLFRRGAEGRRTKPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NSEFIAAVVDRLRAGSAAG
CHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAHKVRLLVCDDNRDFCALLQEYFALQPDMEVVGVAHNGLDAVAAIQEQQPDVVLLDII
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCEEHHHHH
MPYMDGIGVLEQLARTKLSARPRILMLSAFGQEAIARRVMAMGADYYVVKPVDLEILAAR
HHHHCCHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHHHHHHCCCEEEECCCHHHHHHHH
VRQLAWGDALADSPRVPPASHAAGHTLDEVHALLRALGIPPHLKGYRYLGDAILLVLEQP
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
ELLGAVTKGLYPAVARSHGTTASRVERAIRHAVGMAWDRGLEPLRKLFRRGAEGRRTKPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
NSEFIAAVVDRLRAGSAAG
CHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7885226 [H]