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The map label for this gene is yqiR [H]

Identifier: 51892969

GI number: 51892969

Start: 1976310

End: 1978373

Strand: Reverse

Name: yqiR [H]

Synonym: STH1831

Alternate gene names: 51892969

Gene position: 1978373-1976310 (Counterclockwise)

Preceding gene: 51892970

Following gene: 51892968

Centisome position: 55.48

GC content: 69.67

Gene sequence:

>2064_bases
ATGCTGAACGTGGTGATCGTCGGTGCGGGCAAGGGCGGCACGTCGCTGCTGAACGCGCTGCTGAAGATGTCGCGGCAGGT
GCGGGTGCTGGGGGTGGCCGACCGGCGGCCCGACGCCCCGGGCCTCGGCCTGGCGGCGGCCCACGGCATCCCCACGACGA
CCGACTTCACGGGGCTGGTCTGCCTGCCCGAGGTGGACGTCATCGTCGACGCGACGGGACAGCCCGGGCTTGACGAAGAG
ATCCGGCGGCTGAAGTGGCCGCGGGCGGTGGTCATCGAGGGGCTGGCGATGAACCTCATCCTCAGCTTCGTGGAGGAGAG
CCACCGGCTCCTGCGCGCCCTCGAAGAGAGGGAGCTGGAGCGGGACGTGATGCTCGACTCCACCCACGACGCGATCGTGG
CCGTGAACGCCGAGGGCGTCGTCACCCTGCTCAACCGCTCCGCCGAGAAGTTGCTGGGCGTGAGTCGCGACCAGGTGCTG
GGCCGGAGGGCGGCGGACGTGATCCCCAACACCCGGCTGCACGTGGTGCTGGCCACCGGCGAGCCGGAACTCAACCAGCA
GCAGGAGGTGGGCCGCACCACCATCGTCACCAACCGGGTGCCCGTGCGCAACAAGGACGGCCAGGTCGTTGGCGCCGTGG
CCGTGTTCCGGGACATCACCGAGGTCAAGGCCCTCGCGGAGGAGATCACCGGGCTCCGGGAGATGAAGGTGCTCCTGGAG
GCGATCTTCAACTCCACCCAGGACGCGATCTCCGTGGTGGACGAGAACGGCATCGGTTGGATGGTCAACCCCGCCTACTC
AGCCCTGACGGGGTTGAAGCCGGAGGAGGTCATCGGCAAGCCGGCGACAGTGGACATCGACCCGTCGCAGGAGTCGATGC
ACCTGCAGGTGCTGCGCACCCGGCAGCCGGTGCGGAACGTGCCGCTCCGGGTCGGCCCCCGCAAGCGGGAGGTCGTGGTC
AACGTGGCGCCGATCCTGGTGGACGGGAAGCTGAAGGGCTCGGTGGGCGTGATCCGGGACGTCTCCGAGATCGCGCGGCT
CTCCGCCGAGCTGGAGCAGCACCGCAAGCTCCTGCGCCGGCTGACCTCCTCGTACACCTTCGACGAGATCATCGCCGACA
GCCCGGTGATGCAGCAGGCGGTGGAGCAGGCCCGGCGGGCGGCGGAGACCCCTGCCACCGTCCTGCTCCGGGGCGAGAGC
GGCACGGGCAAGGAGCTCTTTGCGCACGCCATCCACAACGCCTCCAGCCGGCGGAGGGGCCAGTTCATCCGGGTCAACTG
CGCCGCGATCGCGGAGTCGCTGCTGGAGTCGGAGCTCTTCGGCTACGCCGAGGGCGCCTTCACCGGCGCCCGCAAGGGCG
GCAAGCGGGGGCTGTTCGAGGAGGCGCACGGCGGCACCCTCTTCCTGGACGAGGTGGGCGAGCTGCCGCCGGGGCTGCAG
GCGAAGCTGCTCCGGGTGCTGCAGGAGAAGGAGATCGTGCGGGTGGGTGAGGCGAAGCCCATCAAGGTCGACGTGCGGGT
GATCGCCGCGACCAACGCCCCGCTGGAGGAGATGATCGCCAAGGGCACGTTCCGGGAGGATCTCTACTACCGGCTGAACG
TCATCCCCATCGTCATCCCGCCCCTGCGGCACCGGCAGGAGGACATCCCCAAGCTGGTCAAGCACCTGATTGAGAAACTG
AACAAGGAGTACGGCCGCAGCGTGCAGGACATCGCCCCCGACGCCCTGCGGGTGCTGATGGATTACCACTGGCCGGGCAA
CGTGCGGGAGCTGGAGAACATCATCGGCCGGGCGATGATCGCCATGTCGGTGACCGACACCATCATCGAACGGCGGTTCC
TGCCGCCGCTGGGCATTGCCCCGGCCCCCGAGGTCCCACCCGCGGAGGACGGCCGGGCCCGCCCGGGGGTGCGGCCGCTG
TTCGAGGTGGTGGCGGAGGCGGAGAAGGCGGCCCTCCTGCAGGCGCTGCAGGAGACCAAGGGCAACAAGACCGAGGCCGC
CCGCCGGCTGGCGATCGCCCCGCGGACCCTCTACTACAAGCTGGAACGGTATGGGCTCATGTAG

Upstream 100 bases:

>100_bases
GCCGGCTCCGCGGCGGGCTGAGGCTCCGCGCACACGCTGCAGGGAATTGCGCTTCTTCAGCCGAAATGGTCTGCAAGAGA
GTGCAGCAGGGGTGTGGCGG

Downstream 100 bases:

>100_bases
TCGGGCGAGGTCACCGGGCCTCGCCTTTTTGCGCGCCGACGGGGTTCTGCACATTTTTGCAGGCACCATGCTGCAGAACG
ATGCAGGATCCTGCGTATGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MLNVVIVGAGKGGTSLLNALLKMSRQVRVLGVADRRPDAPGLGLAAAHGIPTTTDFTGLVCLPEVDVIVDATGQPGLDEE
IRRLKWPRAVVIEGLAMNLILSFVEESHRLLRALEERELERDVMLDSTHDAIVAVNAEGVVTLLNRSAEKLLGVSRDQVL
GRRAADVIPNTRLHVVLATGEPELNQQQEVGRTTIVTNRVPVRNKDGQVVGAVAVFRDITEVKALAEEITGLREMKVLLE
AIFNSTQDAISVVDENGIGWMVNPAYSALTGLKPEEVIGKPATVDIDPSQESMHLQVLRTRQPVRNVPLRVGPRKREVVV
NVAPILVDGKLKGSVGVIRDVSEIARLSAELEQHRKLLRRLTSSYTFDEIIADSPVMQQAVEQARRAAETPATVLLRGES
GTGKELFAHAIHNASSRRRGQFIRVNCAAIAESLLESELFGYAEGAFTGARKGGKRGLFEEAHGGTLFLDEVGELPPGLQ
AKLLRVLQEKEIVRVGEAKPIKVDVRVIAATNAPLEEMIAKGTFREDLYYRLNVIPIVIPPLRHRQEDIPKLVKHLIEKL
NKEYGRSVQDIAPDALRVLMDYHWPGNVRELENIIGRAMIAMSVTDTIIERRFLPPLGIAPAPEVPPAEDGRARPGVRPL
FEVVAEAEKAALLQALQETKGNKTEAARRLAIAPRTLYYKLERYGLM

Sequences:

>Translated_687_residues
MLNVVIVGAGKGGTSLLNALLKMSRQVRVLGVADRRPDAPGLGLAAAHGIPTTTDFTGLVCLPEVDVIVDATGQPGLDEE
IRRLKWPRAVVIEGLAMNLILSFVEESHRLLRALEERELERDVMLDSTHDAIVAVNAEGVVTLLNRSAEKLLGVSRDQVL
GRRAADVIPNTRLHVVLATGEPELNQQQEVGRTTIVTNRVPVRNKDGQVVGAVAVFRDITEVKALAEEITGLREMKVLLE
AIFNSTQDAISVVDENGIGWMVNPAYSALTGLKPEEVIGKPATVDIDPSQESMHLQVLRTRQPVRNVPLRVGPRKREVVV
NVAPILVDGKLKGSVGVIRDVSEIARLSAELEQHRKLLRRLTSSYTFDEIIADSPVMQQAVEQARRAAETPATVLLRGES
GTGKELFAHAIHNASSRRRGQFIRVNCAAIAESLLESELFGYAEGAFTGARKGGKRGLFEEAHGGTLFLDEVGELPPGLQ
AKLLRVLQEKEIVRVGEAKPIKVDVRVIAATNAPLEEMIAKGTFREDLYYRLNVIPIVIPPLRHRQEDIPKLVKHLIEKL
NKEYGRSVQDIAPDALRVLMDYHWPGNVRELENIIGRAMIAMSVTDTIIERRFLPPLGIAPAPEVPPAEDGRARPGVRPL
FEVVAEAEKAALLQALQETKGNKTEAARRLAIAPRTLYYKLERYGLM
>Mature_687_residues
MLNVVIVGAGKGGTSLLNALLKMSRQVRVLGVADRRPDAPGLGLAAAHGIPTTTDFTGLVCLPEVDVIVDATGQPGLDEE
IRRLKWPRAVVIEGLAMNLILSFVEESHRLLRALEERELERDVMLDSTHDAIVAVNAEGVVTLLNRSAEKLLGVSRDQVL
GRRAADVIPNTRLHVVLATGEPELNQQQEVGRTTIVTNRVPVRNKDGQVVGAVAVFRDITEVKALAEEITGLREMKVLLE
AIFNSTQDAISVVDENGIGWMVNPAYSALTGLKPEEVIGKPATVDIDPSQESMHLQVLRTRQPVRNVPLRVGPRKREVVV
NVAPILVDGKLKGSVGVIRDVSEIARLSAELEQHRKLLRRLTSSYTFDEIIADSPVMQQAVEQARRAAETPATVLLRGES
GTGKELFAHAIHNASSRRRGQFIRVNCAAIAESLLESELFGYAEGAFTGARKGGKRGLFEEAHGGTLFLDEVGELPPGLQ
AKLLRVLQEKEIVRVGEAKPIKVDVRVIAATNAPLEEMIAKGTFREDLYYRLNVIPIVIPPLRHRQEDIPKLVKHLIEKL
NKEYGRSVQDIAPDALRVLMDYHWPGNVRELENIIGRAMIAMSVTDTIIERRFLPPLGIAPAPEVPPAEDGRARPGVRPL
FEVVAEAEKAALLQALQETKGNKTEAARRLAIAPRTLYYKLERYGLM

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=332, Percent_Identity=48.4939759036145, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=47.7707006369427, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI87082117, Length=366, Percent_Identity=43.4426229508197, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1789233, Length=327, Percent_Identity=44.0366972477064, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=46.1300309597523, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=45.0793650793651, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1786524, Length=363, Percent_Identity=40.771349862259, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790299, Length=331, Percent_Identity=41.6918429003021, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=40.3125, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=42.5925925925926, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=308, Percent_Identity=38.3116883116883, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081858, Length=474, Percent_Identity=30.379746835443, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=36.328125, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 75408; Mature: 75408

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNVVIVGAGKGGTSLLNALLKMSRQVRVLGVADRRPDAPGLGLAAAHGIPTTTDFTGLV
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEE
CLPEVDVIVDATGQPGLDEEIRRLKWPRAVVIEGLAMNLILSFVEESHRLLRALEERELE
EECCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVMLDSTHDAIVAVNAEGVVTLLNRSAEKLLGVSRDQVLGRRAADVIPNTRLHVVLATG
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECC
EPELNQQQEVGRTTIVTNRVPVRNKDGQVVGAVAVFRDITEVKALAEEITGLREMKVLLE
CCCCCHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFNSTQDAISVVDENGIGWMVNPAYSALTGLKPEEVIGKPATVDIDPSQESMHLQVLRT
HHHCCCHHHHHHHCCCCCCEEECHHHHHHHCCCHHHHCCCCCEEECCCCCCHHHHHHHHH
RQPVRNVPLRVGPRKREVVVNVAPILVDGKLKGSVGVIRDVSEIARLSAELEQHRKLLRR
CCHHHCCCCEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSSYTFDEIIADSPVMQQAVEQARRAAETPATVLLRGESGTGKELFAHAIHNASSRRRG
HHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHHCCC
QFIRVNCAAIAESLLESELFGYAEGAFTGARKGGKRGLFEEAHGGTLFLDEVGELPPGLQ
CEEEEEHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHCCCCEEEECHHCCCCCCHH
AKLLRVLQEKEIVRVGEAKPIKVDVRVIAATNAPLEEMIAKGTFREDLYYRLNVIPIVIP
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEEEEC
PLRHRQEDIPKLVKHLIEKLNKEYGRSVQDIAPDALRVLMDYHWPGNVRELENIIGRAMI
CHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AMSVTDTIIERRFLPPLGIAPAPEVPPAEDGRARPGVRPLFEVVAEAEKAALLQALQETK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GNKTEAARRLAIAPRTLYYKLERYGLM
CCHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLNVVIVGAGKGGTSLLNALLKMSRQVRVLGVADRRPDAPGLGLAAAHGIPTTTDFTGLV
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEE
CLPEVDVIVDATGQPGLDEEIRRLKWPRAVVIEGLAMNLILSFVEESHRLLRALEERELE
EECCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVMLDSTHDAIVAVNAEGVVTLLNRSAEKLLGVSRDQVLGRRAADVIPNTRLHVVLATG
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEECC
EPELNQQQEVGRTTIVTNRVPVRNKDGQVVGAVAVFRDITEVKALAEEITGLREMKVLLE
CCCCCHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFNSTQDAISVVDENGIGWMVNPAYSALTGLKPEEVIGKPATVDIDPSQESMHLQVLRT
HHHCCCHHHHHHHCCCCCCEEECHHHHHHHCCCHHHHCCCCCEEECCCCCCHHHHHHHHH
RQPVRNVPLRVGPRKREVVVNVAPILVDGKLKGSVGVIRDVSEIARLSAELEQHRKLLRR
CCHHHCCCCEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSSYTFDEIIADSPVMQQAVEQARRAAETPATVLLRGESGTGKELFAHAIHNASSRRRG
HHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHHCCC
QFIRVNCAAIAESLLESELFGYAEGAFTGARKGGKRGLFEEAHGGTLFLDEVGELPPGLQ
CEEEEEHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHCCCCEEEECHHCCCCCCHH
AKLLRVLQEKEIVRVGEAKPIKVDVRVIAATNAPLEEMIAKGTFREDLYYRLNVIPIVIP
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEEEEC
PLRHRQEDIPKLVKHLIEKLNKEYGRSVQDIAPDALRVLMDYHWPGNVRELENIIGRAMI
CHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AMSVTDTIIERRFLPPLGIAPAPEVPPAEDGRARPGVRPLFEVVAEAEKAALLQALQETK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GNKTEAARRLAIAPRTLYYKLERYGLM
CCHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]