Click here to switch to the map view.

The map label for this gene is buk1 [H]

Identifier: 51892964

GI number: 51892964

Start: 1970744

End: 1971829

Strand: Reverse

Name: buk1 [H]

Synonym: STH1826

Alternate gene names: 51892964

Gene position: 1971829-1970744 (Counterclockwise)

Preceding gene: 51892965

Following gene: 51892963

Centisome position: 55.29

GC content: 74.86

Gene sequence:

>1086_bases
TTGCAGCAGCGCCTGCTGATCATCAACCCGGGCTCAACCTCCACGAAGATCGCCGTGTACGACGACGACTCCCCCCTGTT
CGCCGAGACGCTGCGCCACAGCGCGGCCGACCTGGCGTGTTTCCGGGACGTCGCCGCCCAGTTCCCCTTCCGGCGGGACC
TGATCCTGGAGGCTCTCGACGCCCACGGCGTGTCGCTCTCCTCGCTCACCGCCGTGGTGGGGCGCGGCGGGCTCCTGCGG
CCCGTGCGCGGGGGAACCTACCGGGTGGACGCGGCCATGCTGGCGGAGCTCTCCCGGGCTGCCCACGGCGAGCACGCGTC
CAACCTGGGCGCCCTCCTCGCCCACGAGATCGCCCAGGCCGCGGGCGGCGTGCCGGCCTTCATCGTCGACCCCGTGGTGG
TGGACGAGCTGGAGCCGGTGGCCAGGCTCACCGGCCTGCCGGAGATGCCGCGGCGGTCGGTCTTCCACGCCCTCAACCAG
AAGGCGGTGGCGCGGCGGGCCGCGGCCGACCTGGGCCGCGCCTACACCGAGGTCAACCTGGTCGTCGTCCACCTGGGCGG
CGGGATCTCGGTGGGGGCGCACCGGCGCGGGCGGGTCGTCGACGTCAACAACGCGCTGGACGGCGAGGGGCCGATGGCGC
CGGAGCGGGCAGGCACGGTGCCCAGCCTGGGGCTGGTCCACCTGGCGTTCTCCTGGCAGCACACGCTGCGGGAGGTGGGG
CGGATGCTGGTCGGCCGCGGCGGTCTGGTGGCGCACGTGGGCACCAACGACGCCCGGCGGGTGGAGGAGCGGATCGCCGC
GGGCGACGAGGCAGCCCGGGTCGCGTACCGGGCCATGGCGTACCAGGTGGCCAAGGAGGTGGGCCGGGCGGCGGTGGCCC
TGGGCGGCCAGGTGGACCGCATCGTGCTGACGGGCGGACTGGCCCACTCCGAGATGCTGACGGGCTGGATCGCGGAGCAG
GTGGAGTGGATCGCTCCGGTGGCGGTCTACCCCGGCGAGGACGAGATGGCCGCGCTGGCGGCCGGCGCCCTGCGGGTGCT
GCGGGGCGAGGAGCCGGCGCAGGTGTACGGGGAGGCAGGCGAGTGA

Upstream 100 bases:

>100_bases
CTACCTGGCCGAGTAAACGCAGGGGGCCGGAGGGGGAGCGGGCCTCCCTCTCCGGCCCCCGCACGGCGACCCTGAAGCAG
CGAAAGGACGAGGAGCGAAC

Downstream 100 bases:

>100_bases
GAGTCATCCGACAGGAAGAGATCTACCGGGGCAGAGTGATTGCGGTCCGAAGGGACCTGATCGACCTGGACGGGAAGGAA
CGGACCTGGGACGTGGTGGC

Product: butyrate kinase

Products: NA

Alternate protein names: BK 1; Branched-chain carboxylic acid kinase 1 [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQQRLLIINPGSTSTKIAVYDDDSPLFAETLRHSAADLACFRDVAAQFPFRRDLILEALDAHGVSLSSLTAVVGRGGLLR
PVRGGTYRVDAAMLAELSRAAHGEHASNLGALLAHEIAQAAGGVPAFIVDPVVVDELEPVARLTGLPEMPRRSVFHALNQ
KAVARRAAADLGRAYTEVNLVVVHLGGGISVGAHRRGRVVDVNNALDGEGPMAPERAGTVPSLGLVHLAFSWQHTLREVG
RMLVGRGGLVAHVGTNDARRVEERIAAGDEAARVAYRAMAYQVAKEVGRAAVALGGQVDRIVLTGGLAHSEMLTGWIAEQ
VEWIAPVAVYPGEDEMAALAAGALRVLRGEEPAQVYGEAGE

Sequences:

>Translated_361_residues
MQQRLLIINPGSTSTKIAVYDDDSPLFAETLRHSAADLACFRDVAAQFPFRRDLILEALDAHGVSLSSLTAVVGRGGLLR
PVRGGTYRVDAAMLAELSRAAHGEHASNLGALLAHEIAQAAGGVPAFIVDPVVVDELEPVARLTGLPEMPRRSVFHALNQ
KAVARRAAADLGRAYTEVNLVVVHLGGGISVGAHRRGRVVDVNNALDGEGPMAPERAGTVPSLGLVHLAFSWQHTLREVG
RMLVGRGGLVAHVGTNDARRVEERIAAGDEAARVAYRAMAYQVAKEVGRAAVALGGQVDRIVLTGGLAHSEMLTGWIAEQ
VEWIAPVAVYPGEDEMAALAAGALRVLRGEEPAQVYGEAGE
>Mature_361_residues
MQQRLLIINPGSTSTKIAVYDDDSPLFAETLRHSAADLACFRDVAAQFPFRRDLILEALDAHGVSLSSLTAVVGRGGLLR
PVRGGTYRVDAAMLAELSRAAHGEHASNLGALLAHEIAQAAGGVPAFIVDPVVVDELEPVARLTGLPEMPRRSVFHALNQ
KAVARRAAADLGRAYTEVNLVVVHLGGGISVGAHRRGRVVDVNNALDGEGPMAPERAGTVPSLGLVHLAFSWQHTLREVG
RMLVGRGGLVAHVGTNDARRVEERIAAGDEAARVAYRAMAYQVAKEVGRAAVALGGQVDRIVLTGGLAHSEMLTGWIAEQ
VEWIAPVAVYPGEDEMAALAAGALRVLRGEEPAQVYGEAGE

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=332, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788633, Length=159, Percent_Identity=30.188679245283, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR011245 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.7 [H]

Molecular weight: Translated: 38112; Mature: 38112

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRLLIINPGSTSTKIAVYDDDSPLFAETLRHSAADLACFRDVAAQFPFRRDLILEALD
CCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AHGVSLSSLTAVVGRGGLLRPVRGGTYRVDAAMLAELSRAAHGEHASNLGALLAHEIAQA
CCCCCHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGGVPAFIVDPVVVDELEPVARLTGLPEMPRRSVFHALNQKAVARRAAADLGRAYTEVNL
HCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
VVVHLGGGISVGAHRRGRVVDVNNALDGEGPMAPERAGTVPSLGLVHLAFSWQHTLREVG
EEEEECCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RMLVGRGGLVAHVGTNDARRVEERIAAGDEAARVAYRAMAYQVAKEVGRAAVALGGQVDR
HHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IVLTGGLAHSEMLTGWIAEQVEWIAPVAVYPGEDEMAALAAGALRVLRGEEPAQVYGEAG
EEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCC
E
C
>Mature Secondary Structure
MQQRLLIINPGSTSTKIAVYDDDSPLFAETLRHSAADLACFRDVAAQFPFRRDLILEALD
CCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AHGVSLSSLTAVVGRGGLLRPVRGGTYRVDAAMLAELSRAAHGEHASNLGALLAHEIAQA
CCCCCHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AGGVPAFIVDPVVVDELEPVARLTGLPEMPRRSVFHALNQKAVARRAAADLGRAYTEVNL
HCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
VVVHLGGGISVGAHRRGRVVDVNNALDGEGPMAPERAGTVPSLGLVHLAFSWQHTLREVG
EEEEECCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RMLVGRGGLVAHVGTNDARRVEERIAAGDEAARVAYRAMAYQVAKEVGRAAVALGGQVDR
HHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IVLTGGLAHSEMLTGWIAEQVEWIAPVAVYPGEDEMAALAAGALRVLRGEEPAQVYGEAG
EEEECCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]