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The map label for this gene is cca [H]

Identifier: 51892943

GI number: 51892943

Start: 1946712

End: 1949384

Strand: Reverse

Name: cca [H]

Synonym: STH1805

Alternate gene names: 51892943

Gene position: 1949384-1946712 (Counterclockwise)

Preceding gene: 51892946

Following gene: 51892942

Centisome position: 54.66

GC content: 73.4

Gene sequence:

>2673_bases
ATGCGCCGTGCAGGCGCTTCCGGGAGACCAGAAGGGACCATGCAGATCATCGTGCCGCATACGAATACCGACCTGGATGC
CATCGGCGCAGCCATCGGGGCCCAGGTGCTGTACCCCAAGGCGCAGATCGTGCTGCCGGGCACGGCCAACCCGATGGCCG
CCGAGTTCATCTCCCTGCACCGGTACAACCTGCGGGTCTACCGGGTGAAGGACATTGACCTCACGCAGGTGCAGCGGGCG
ATAGTCGTGGATACCGCCGACGCTGCCCGGCTCGGGCCCCTGCGGACGCTGTTGCCCAACGTGGAGCTGCACCTGTACGA
CCATCACCCCGCGGAGGCCGCCGACCTGCAGGGCCGGCTGGAGGTGCGGGCCCCGGTGGGGGCCACCTGCACCCTGATCG
CCGAACTGATCGAGGAGGCCGGGGCGCCGCTGACCCCGTTCCAGGCGACGGCCCTGCTGGTGGGCATCTACGCCGACACC
GGCTCGCTGAGCCTCCTGGGCACCACCGACCGGGACGCCCGGGCCGCGGGGTTTCTGCTCTCGCGCGGCGCGAGCCTGCA
GGCGGCCGCCCGCTTCATGGAGGTGTCCCTGTCGCCGGCCCAGCAGACCCTCCTGCAGCAGCTGCAGAACCGGGGCCGCT
GGGTGAACGTGCACGGCGCCCGGATCCGGCTGCTGGTGGCCGAGGTGCCGGAGTACGTGGGCGGTCTCAATCTGGTGGTG
CACCGGCTCATGGAGCTGGAACCGGTGCCGGCCCTGTTCGCCGCGGTGCGCATGGACGACCGGGTGCACCTGGTGGGCCG
GTCGTCCGTCCCGTGGGTGGACGCGGCCCGCGTGATGGCCCGGTTCGGCGGAGGCGGCCACCCCGCCGCGGCCTCCGCCG
TGGTCAAGGGGCTCTCGGTGGAGGAGGCGGCGGAGCGGCTCGAAGAGGTGCTGCCCGACGGCGTCGAGCGGCCGCTGATG
GCCCGGGACGTCATGTCCGCCCCCGTCAAGACGATCCTGGCCCGGAAGCCCATCCGGGATGCGGAGCGGCTCATGCTGCG
CCACGGCCACACGGGCCTGCCGGTGGTGGACGAGCAGGGCCGGGTGGTGGGGGTCGTGTCGCTGCGGGACGTGGAAAAGG
CCCGGCGGCACGGGCTGGAGCACGCCCCGGTCAAGTCGGTGATGCGGTCGCAGGTGATCGCCGTCCACCCCGACACGCCG
GCGGACGAGGTGCAGGAGCTGATGATCGAGCGGGACATCGGCCGGGTGCCGGTGGTGGCCGACGGCAACCTGGTGGGCAT
CATCACCCGCTCGGACATCCTCGGCCTCATCTACGGCGCCCCGCCGCCCCGGTGGCACCGCCGGCTCTACGCGGCGCCGG
ACATGCCCAAAGACCTGCGGGACAAGGCGGTGCAGGAAGCGCTGGAGGCGGTGGAGGCGGCCCCTGCGGGGATTCGCGCC
CTGCTGCGCACCGCCGGGCGGGTCGCAGAGCAGGAGGGGGTCGCGGTGTACGCCGTCGGCGGCTTCGTGCGGGACCTGCT
CCTGGGCCGGCCGAACCTCGACTTCGACATCGTCGTGGAGGGCGACGGCATCGCCTTCGCCCACTCCCTCGCCCGGGCGC
TGGGGGGACGGGTGCAGGAGGTGCCCCGGTTCGGCACCGCGCACATCTACCTGGATGCGGACGACCCGGACCTGCCGTCC
CGGATCGACGTGGCCACGGCCCGGCGGGAGTTCTACGAGCACGCGGCGGCGCTGCCCCGGGTGGAGCACGCGGACCTGCA
CGAGGACCTGTACCGGCGGGACTTCTCCATCAACGCTCTGGCTATCCGACTGGGCTCCGCCGGCCCCTCGGGGCTGATCG
ACTTCTTCGGCGGCCTGAAGGACCTGGCGGCCGGGCAGGTGCGCATCCTCCACACCCTCAGCTTCGTCGAGGACCCGACG
CGGCTGCTCAGGGCCGTGCGGTTCGCCCACCGCTACGGGTTCCGTCTGGAGCGGGAGACGGAGGCCTGCGCCCGCCGCGC
GATTGCCGAGGGTTTCCTGGGGAGGGTGAGCCGCGAGCGGCTGCGCAACGAGCTGCTGCTGCTCCTGCAGGAGCCCGCGG
GCGGCGGGGCGCTGCAGATGCTGGCCGACCTGGGCGGGCTGGAGGACCTTCTGCCCGGCGTGGGCCTGACCCCGGAGGTG
CTGTCGCTTCTGGACGCGGCCGACGGCCTGCCCGAGGCGGAGCCGGAGATCAGCGCCGGCAGCCGGCTGTGGCTGGTCAA
GCTCCTGGTGCTGCTCCACCCGCTCCCGCTGAACCAGGGGGCAGCCCTGGTGAAGCGGCTCCGGCTGAAGCGGGCGGAGT
CCCAGGCCTGCCTGCAGGTGCTCGCCGGGTGGCGAATCGCCCACGACCTGGTGACGGCCCCCCGGCCCGACCCCGCGGCG
ATCGTGGCGCACCTGGACGGCTGGCCGCCGGAGGGGCTGCTGCTCCTGCACCTGCTGGGCGGCGGCGATCGCGTAGCGAC
GTACTGGCGGACGTGGCGCCATATTCGGCTGGACATCACCGGCGCCGACGTGCGGGCCCTGGGGGTGCCCCCCGGGCCTC
AGGTGGGCCGGATCCTGCAGCGGGTGCTGGCCGCCCGGCTCTCGGGCGAGGCCCCGGACCGGGCGGCGCAGTTGGAGCTG
GCCCGCCGCCACGCAGCCCAACAGGAGGAGTGA

Upstream 100 bases:

>100_bases
CAGTGCCTGCTCATTATACCGCAACCCCGTTCGGAGCGCAAGGCCACCTGGAAGATTATGCAGGGTTTGTGCCCCCTGCA
GCCGAATAGTTGTCGATAAC

Downstream 100 bases:

>100_bases
ACCGCTTGGCACTGCCCAGCCTGCAGCAGATCGTGATGCTCATCCCCGGCGTCGTCATGGGCTTCGCGTTCCACGAGTTC
GGTCACGCGCTGGTGGCCAC

Product: putative poly A polymerase

Products: NA

Alternate protein names: tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl- transferase; tRNA nucleotidyltransferase; tRNA-NT [H]

Number of amino acids: Translated: 890; Mature: 890

Protein sequence:

>890_residues
MRRAGASGRPEGTMQIIVPHTNTDLDAIGAAIGAQVLYPKAQIVLPGTANPMAAEFISLHRYNLRVYRVKDIDLTQVQRA
IVVDTADAARLGPLRTLLPNVELHLYDHHPAEAADLQGRLEVRAPVGATCTLIAELIEEAGAPLTPFQATALLVGIYADT
GSLSLLGTTDRDARAAGFLLSRGASLQAAARFMEVSLSPAQQTLLQQLQNRGRWVNVHGARIRLLVAEVPEYVGGLNLVV
HRLMELEPVPALFAAVRMDDRVHLVGRSSVPWVDAARVMARFGGGGHPAAASAVVKGLSVEEAAERLEEVLPDGVERPLM
ARDVMSAPVKTILARKPIRDAERLMLRHGHTGLPVVDEQGRVVGVVSLRDVEKARRHGLEHAPVKSVMRSQVIAVHPDTP
ADEVQELMIERDIGRVPVVADGNLVGIITRSDILGLIYGAPPPRWHRRLYAAPDMPKDLRDKAVQEALEAVEAAPAGIRA
LLRTAGRVAEQEGVAVYAVGGFVRDLLLGRPNLDFDIVVEGDGIAFAHSLARALGGRVQEVPRFGTAHIYLDADDPDLPS
RIDVATARREFYEHAAALPRVEHADLHEDLYRRDFSINALAIRLGSAGPSGLIDFFGGLKDLAAGQVRILHTLSFVEDPT
RLLRAVRFAHRYGFRLERETEACARRAIAEGFLGRVSRERLRNELLLLLQEPAGGGALQMLADLGGLEDLLPGVGLTPEV
LSLLDAADGLPEAEPEISAGSRLWLVKLLVLLHPLPLNQGAALVKRLRLKRAESQACLQVLAGWRIAHDLVTAPRPDPAA
IVAHLDGWPPEGLLLLHLLGGGDRVATYWRTWRHIRLDITGADVRALGVPPGPQVGRILQRVLAARLSGEAPDRAAQLEL
ARRHAAQQEE

Sequences:

>Translated_890_residues
MRRAGASGRPEGTMQIIVPHTNTDLDAIGAAIGAQVLYPKAQIVLPGTANPMAAEFISLHRYNLRVYRVKDIDLTQVQRA
IVVDTADAARLGPLRTLLPNVELHLYDHHPAEAADLQGRLEVRAPVGATCTLIAELIEEAGAPLTPFQATALLVGIYADT
GSLSLLGTTDRDARAAGFLLSRGASLQAAARFMEVSLSPAQQTLLQQLQNRGRWVNVHGARIRLLVAEVPEYVGGLNLVV
HRLMELEPVPALFAAVRMDDRVHLVGRSSVPWVDAARVMARFGGGGHPAAASAVVKGLSVEEAAERLEEVLPDGVERPLM
ARDVMSAPVKTILARKPIRDAERLMLRHGHTGLPVVDEQGRVVGVVSLRDVEKARRHGLEHAPVKSVMRSQVIAVHPDTP
ADEVQELMIERDIGRVPVVADGNLVGIITRSDILGLIYGAPPPRWHRRLYAAPDMPKDLRDKAVQEALEAVEAAPAGIRA
LLRTAGRVAEQEGVAVYAVGGFVRDLLLGRPNLDFDIVVEGDGIAFAHSLARALGGRVQEVPRFGTAHIYLDADDPDLPS
RIDVATARREFYEHAAALPRVEHADLHEDLYRRDFSINALAIRLGSAGPSGLIDFFGGLKDLAAGQVRILHTLSFVEDPT
RLLRAVRFAHRYGFRLERETEACARRAIAEGFLGRVSRERLRNELLLLLQEPAGGGALQMLADLGGLEDLLPGVGLTPEV
LSLLDAADGLPEAEPEISAGSRLWLVKLLVLLHPLPLNQGAALVKRLRLKRAESQACLQVLAGWRIAHDLVTAPRPDPAA
IVAHLDGWPPEGLLLLHLLGGGDRVATYWRTWRHIRLDITGADVRALGVPPGPQVGRILQRVLAARLSGEAPDRAAQLEL
ARRHAAQQEE
>Mature_890_residues
MRRAGASGRPEGTMQIIVPHTNTDLDAIGAAIGAQVLYPKAQIVLPGTANPMAAEFISLHRYNLRVYRVKDIDLTQVQRA
IVVDTADAARLGPLRTLLPNVELHLYDHHPAEAADLQGRLEVRAPVGATCTLIAELIEEAGAPLTPFQATALLVGIYADT
GSLSLLGTTDRDARAAGFLLSRGASLQAAARFMEVSLSPAQQTLLQQLQNRGRWVNVHGARIRLLVAEVPEYVGGLNLVV
HRLMELEPVPALFAAVRMDDRVHLVGRSSVPWVDAARVMARFGGGGHPAAASAVVKGLSVEEAAERLEEVLPDGVERPLM
ARDVMSAPVKTILARKPIRDAERLMLRHGHTGLPVVDEQGRVVGVVSLRDVEKARRHGLEHAPVKSVMRSQVIAVHPDTP
ADEVQELMIERDIGRVPVVADGNLVGIITRSDILGLIYGAPPPRWHRRLYAAPDMPKDLRDKAVQEALEAVEAAPAGIRA
LLRTAGRVAEQEGVAVYAVGGFVRDLLLGRPNLDFDIVVEGDGIAFAHSLARALGGRVQEVPRFGTAHIYLDADDPDLPS
RIDVATARREFYEHAAALPRVEHADLHEDLYRRDFSINALAIRLGSAGPSGLIDFFGGLKDLAAGQVRILHTLSFVEDPT
RLLRAVRFAHRYGFRLERETEACARRAIAEGFLGRVSRERLRNELLLLLQEPAGGGALQMLADLGGLEDLLPGVGLTPEV
LSLLDAADGLPEAEPEISAGSRLWLVKLLVLLHPLPLNQGAALVKRLRLKRAESQACLQVLAGWRIAHDLVTAPRPDPAA
IVAHLDGWPPEGLLLLHLLGGGDRVATYWRTWRHIRLDITGADVRALGVPPGPQVGRILQRVLAARLSGEAPDRAAQLEL
ARRHAAQQEE

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG0617

COG function: function code J; tRNA nucleotidyltransferase/poly(A) polymerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081691, Length=239, Percent_Identity=31.3807531380753, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789436, Length=255, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321016, Length=230, Percent_Identity=30, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023068
- InterPro:   IPR002646 [H]

Pfam domain/function: PF01743 PolyA_pol [H]

EC number: =2.7.7.21; =2.7.7.25 [H]

Molecular weight: Translated: 96469; Mature: 96469

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAGASGRPEGTMQIIVPHTNTDLDAIGAAIGAQVLYPKAQIVLPGTANPMAAEFISLH
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RYNLRVYRVKDIDLTQVQRAIVVDTADAARLGPLRTLLPNVELHLYDHHPAEAADLQGRL
HEEEEEEEEECCCHHHHHHHHEEECCCHHHHCHHHHHCCCCEEEEEECCCCCCCCCCCCE
EVRAPVGATCTLIAELIEEAGAPLTPFQATALLVGIYADTGSLSLLGTTDRDARAAGFLL
EEECCCCHHHHHHHHHHHHCCCCCCCHHHHEEEEEEEECCCCEEEEECCCCCHHHHHHHH
SRGASLQAAARFMEVSLSPAQQTLLQQLQNRGRWVNVHGARIRLLVAEVPEYVGGLNLVV
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHHHHCHHHHHH
HRLMELEPVPALFAAVRMDDRVHLVGRSSVPWVDAARVMARFGGGGHPAAASAVVKGLSV
HHHHHCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCH
EEAAERLEEVLPDGVERPLMARDVMSAPVKTILARKPIRDAERLMLRHGHTGLPVVDEQG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCC
RVVGVVSLRDVEKARRHGLEHAPVKSVMRSQVIAVHPDTPADEVQELMIERDIGRVPVVA
CEEEEEEHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCEEE
DGNLVGIITRSDILGLIYGAPPPRWHRRLYAAPDMPKDLRDKAVQEALEAVEAAPAGIRA
CCCEEEEEECCCEEEEEECCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
LLRTAGRVAEQEGVAVYAVGGFVRDLLLGRPNLDFDIVVEGDGIAFAHSLARALGGRVQE
HHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHH
VPRFGTAHIYLDADDPDLPSRIDVATARREFYEHAAALPRVEHADLHEDLYRRDFSINAL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
AIRLGSAGPSGLIDFFGGLKDLAAGQVRILHTLSFVEDPTRLLRAVRFAHRYGFRLERET
EEEECCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHH
EACARRAIAEGFLGRVSRERLRNELLLLLQEPAGGGALQMLADLGGLEDLLPGVGLTPEV
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCCHHH
LSLLDAADGLPEAEPEISAGSRLWLVKLLVLLHPLPLNQGAALVKRLRLKRAESQACLQV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGWRIAHDLVTAPRPDPAAIVAHLDGWPPEGLLLLHLLGGGDRVATYWRTWRHIRLDIT
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCEEEEEEEE
GADVRALGVPPGPQVGRILQRVLAARLSGEAPDRAAQLELARRHAAQQEE
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRAGASGRPEGTMQIIVPHTNTDLDAIGAAIGAQVLYPKAQIVLPGTANPMAAEFISLH
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
RYNLRVYRVKDIDLTQVQRAIVVDTADAARLGPLRTLLPNVELHLYDHHPAEAADLQGRL
HEEEEEEEEECCCHHHHHHHHEEECCCHHHHCHHHHHCCCCEEEEEECCCCCCCCCCCCE
EVRAPVGATCTLIAELIEEAGAPLTPFQATALLVGIYADTGSLSLLGTTDRDARAAGFLL
EEECCCCHHHHHHHHHHHHCCCCCCCHHHHEEEEEEEECCCCEEEEECCCCCHHHHHHHH
SRGASLQAAARFMEVSLSPAQQTLLQQLQNRGRWVNVHGARIRLLVAEVPEYVGGLNLVV
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHHHHCHHHHHH
HRLMELEPVPALFAAVRMDDRVHLVGRSSVPWVDAARVMARFGGGGHPAAASAVVKGLSV
HHHHHCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCH
EEAAERLEEVLPDGVERPLMARDVMSAPVKTILARKPIRDAERLMLRHGHTGLPVVDEQG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCC
RVVGVVSLRDVEKARRHGLEHAPVKSVMRSQVIAVHPDTPADEVQELMIERDIGRVPVVA
CEEEEEEHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCEEE
DGNLVGIITRSDILGLIYGAPPPRWHRRLYAAPDMPKDLRDKAVQEALEAVEAAPAGIRA
CCCEEEEEECCCEEEEEECCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
LLRTAGRVAEQEGVAVYAVGGFVRDLLLGRPNLDFDIVVEGDGIAFAHSLARALGGRVQE
HHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHH
VPRFGTAHIYLDADDPDLPSRIDVATARREFYEHAAALPRVEHADLHEDLYRRDFSINAL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
AIRLGSAGPSGLIDFFGGLKDLAAGQVRILHTLSFVEDPTRLLRAVRFAHRYGFRLERET
EEEECCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHH
EACARRAIAEGFLGRVSRERLRNELLLLLQEPAGGGALQMLADLGGLEDLLPGVGLTPEV
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCCHHH
LSLLDAADGLPEAEPEISAGSRLWLVKLLVLLHPLPLNQGAALVKRLRLKRAESQACLQV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGWRIAHDLVTAPRPDPAAIVAHLDGWPPEGLLLLHLLGGGDRVATYWRTWRHIRLDIT
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCEEEEEEEE
GADVRALGVPPGPQVGRILQRVLAARLSGEAPDRAAQLELARRHAAQQEE
CCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA