Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 51892946

GI number: 51892946

Start: 1951493

End: 1952701

Strand: Reverse

Name: macB [H]

Synonym: STH1808

Alternate gene names: 51892946

Gene position: 1952701-1951493 (Counterclockwise)

Preceding gene: 51892947

Following gene: 51892943

Centisome position: 54.76

GC content: 67.25

Gene sequence:

>1209_bases
ATGAACCTGCTGGAAACCTTCAGCGTCGCGCTTTCGGCCCTGTGGGCCAACAAGCTGCGCTCGGCGCTGACCATGCTGGG
GCTGATCATCGGGGTCGGCTCGGTGATTGCCATCATCGCCATCGGCAGGGGAACCCAGAAGGCGGTGGCCGCCGAGCTGG
ATGCGCTCAATGGCGGCGTCTTCCAGCTCATGGCGACCCCCGGGTGGTCGGAGGATGGCCAGCCCACGGCGAGGCTGCGC
ATGTTCCGCGACGATGACATTGCGCTCCTTAAGGAAGCCCTGCCGGAGATCGACCTGATCGACCCGCAGGTGGGCATGAG
CGGCCGGATCACCTTCGGCCGGGAGGTCGAGTGGTGGGACTGGATCCGGGGCGCGGGCGCGGATACCGCGGCCCTGATGA
ACATCCAGCTCTCGGCCGGCCGCTGGTTCACCGAGGAGGAGATCGCCCGGGGCGACCGGGTGATGGTGCTCTCGGCCAGC
CGTGTGGAGTACATCCTGGGGGAGGGCGTCAATCCCCTGGGGATCGAGCTGATGGTCAATGGCTACCCCTTCCAGATCAT
CGGCGTGATCGCACCCAACACCGGCATGCTGTCGCAACTGCTGGGCGGCCAGGGCGGCGACTTCTACGTCCCGCGCAGCT
ACATCACCCGGGTGACCGGCCAGAACAGCTACGATCACCTGACGGTGCGGGTCCGGGACGGCTACGACCCGGTGGAGGTC
AAGGACCTGGCTGTGCGGGTGATGGAGCGGCTCTACCCCGGCACGGGGTACGAGGCCTACATCTGGACCGACTTCATGGG
CGAGTTCAACCAGGTGATCTCGATCGTGACCGGCGTGATGGCGGCCATCGCCGGCATCTCGCTGGTGGTGGGCGGCGTCG
GCATCATGAACATCATGATGGTCTCGGTGACCGAGCGCACCCGGGAGATCGGTCTGCGCAAGGCCATCGGCGCCCGGCGC
CGGGACATCCTGATGCAGTTCCTGGTGGAGGCGCTCACCCTCTGCCTGATCGGCGGCGGCATCGGCATCGTGCTGGCCGC
AGGCCCGGTGACCATCGCCGCCCGGTACCTGGAGACGCCACTCAGCCTCGACCTCTACGCCATCGCCCTGGCGCTGGGCT
TTTCTGCCGCGGTGGGGCTGATCTTCGGCGTCTACCCGGCGGTGAAGGCCGCGCGTATGGATCCCATCGAGGCGCTCCGG
TACGAGTAG

Upstream 100 bases:

>100_bases
TCATGGGCGGCCCCACGGGCCCGGGCGGCGGGCGGATGCGGACGGTGCCCGGGGGTGTCCGGGCTGTTCCGCTGGGGCTC
GCGACGGGGGGCGCAGCGCG

Downstream 100 bases:

>100_bases
CGGCCGGGCCGGCGGGTGTCGGGGGCGGTTTCTGATCGCAGGCGCGAAGGGGGCGGTGCAGCTGATGCACCGCCCCCTTC
CTTTACGCTCTGTGGGTTCG

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNLLETFSVALSALWANKLRSALTMLGLIIGVGSVIAIIAIGRGTQKAVAAELDALNGGVFQLMATPGWSEDGQPTARLR
MFRDDDIALLKEALPEIDLIDPQVGMSGRITFGREVEWWDWIRGAGADTAALMNIQLSAGRWFTEEEIARGDRVMVLSAS
RVEYILGEGVNPLGIELMVNGYPFQIIGVIAPNTGMLSQLLGGQGGDFYVPRSYITRVTGQNSYDHLTVRVRDGYDPVEV
KDLAVRVMERLYPGTGYEAYIWTDFMGEFNQVISIVTGVMAAIAGISLVVGGVGIMNIMMVSVTERTREIGLRKAIGARR
RDILMQFLVEALTLCLIGGGIGIVLAAGPVTIAARYLETPLSLDLYAIALALGFSAAVGLIFGVYPAVKAARMDPIEALR
YE

Sequences:

>Translated_402_residues
MNLLETFSVALSALWANKLRSALTMLGLIIGVGSVIAIIAIGRGTQKAVAAELDALNGGVFQLMATPGWSEDGQPTARLR
MFRDDDIALLKEALPEIDLIDPQVGMSGRITFGREVEWWDWIRGAGADTAALMNIQLSAGRWFTEEEIARGDRVMVLSAS
RVEYILGEGVNPLGIELMVNGYPFQIIGVIAPNTGMLSQLLGGQGGDFYVPRSYITRVTGQNSYDHLTVRVRDGYDPVEV
KDLAVRVMERLYPGTGYEAYIWTDFMGEFNQVISIVTGVMAAIAGISLVVGGVGIMNIMMVSVTERTREIGLRKAIGARR
RDILMQFLVEALTLCLIGGGIGIVLAAGPVTIAARYLETPLSLDLYAIALALGFSAAVGLIFGVYPAVKAARMDPIEALR
YE
>Mature_402_residues
MNLLETFSVALSALWANKLRSALTMLGLIIGVGSVIAIIAIGRGTQKAVAAELDALNGGVFQLMATPGWSEDGQPTARLR
MFRDDDIALLKEALPEIDLIDPQVGMSGRITFGREVEWWDWIRGAGADTAALMNIQLSAGRWFTEEEIARGDRVMVLSAS
RVEYILGEGVNPLGIELMVNGYPFQIIGVIAPNTGMLSQLLGGQGGDFYVPRSYITRVTGQNSYDHLTVRVRDGYDPVEV
KDLAVRVMERLYPGTGYEAYIWTDFMGEFNQVISIVTGVMAAIAGISLVVGGVGIMNIMMVSVTERTREIGLRKAIGARR
RDILMQFLVEALTLCLIGGGIGIVLAAGPVTIAARYLETPLSLDLYAIALALGFSAAVGLIFGVYPAVKAARMDPIEALR
YE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=402, Percent_Identity=31.592039800995, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43438; Mature: 43438

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLETFSVALSALWANKLRSALTMLGLIIGVGSVIAIIAIGRGTQKAVAAELDALNGGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCE
FQLMATPGWSEDGQPTARLRMFRDDDIALLKEALPEIDLIDPQVGMSGRITFGREVEWWD
EEEEECCCCCCCCCCHHHEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHH
WIRGAGADTAALMNIQLSAGRWFTEEEIARGDRVMVLSASRVEYILGEGVNPLGIELMVN
HHCCCCCCCEEEEEEEECCCCCCCHHHHCCCCEEEEEECCHHHHHHCCCCCCCEEEEEEC
GYPFQIIGVIAPNTGMLSQLLGGQGGDFYVPRSYITRVTGQNSYDHLTVRVRDGYDPVEV
CCCEEEEEEEECCCHHHHHHHCCCCCCEECCHHHHHHHCCCCCCCEEEEEEECCCCCCHH
KDLAVRVMERLYPGTGYEAYIWTDFMGEFNQVISIVTGVMAAIAGISLVVGGVGIMNIMM
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGLRKAIGARRRDILMQFLVEALTLCLIGGGIGIVLAAGPVTIAARYLETP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
LSLDLYAIALALGFSAAVGLIFGVYPAVKAARMDPIEALRYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MNLLETFSVALSALWANKLRSALTMLGLIIGVGSVIAIIAIGRGTQKAVAAELDALNGGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCE
FQLMATPGWSEDGQPTARLRMFRDDDIALLKEALPEIDLIDPQVGMSGRITFGREVEWWD
EEEEECCCCCCCCCCHHHEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHH
WIRGAGADTAALMNIQLSAGRWFTEEEIARGDRVMVLSASRVEYILGEGVNPLGIELMVN
HHCCCCCCCEEEEEEEECCCCCCCHHHHCCCCEEEEEECCHHHHHHCCCCCCCEEEEEEC
GYPFQIIGVIAPNTGMLSQLLGGQGGDFYVPRSYITRVTGQNSYDHLTVRVRDGYDPVEV
CCCEEEEEEEECCCHHHHHHHCCCCCCEECCHHHHHHHCCCCCCCEEEEEEECCCCCCHH
KDLAVRVMERLYPGTGYEAYIWTDFMGEFNQVISIVTGVMAAIAGISLVVGGVGIMNIMM
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVTERTREIGLRKAIGARRRDILMQFLVEALTLCLIGGGIGIVLAAGPVTIAARYLETP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
LSLDLYAIALALGFSAAVGLIFGVYPAVKAARMDPIEALRYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA