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The map label for this gene is 51892913

Identifier: 51892913

GI number: 51892913

Start: 1919850

End: 1920779

Strand: Reverse

Name: 51892913

Synonym: STH1775

Alternate gene names: NA

Gene position: 1920779-1919850 (Counterclockwise)

Preceding gene: 51892914

Following gene: 51892912

Centisome position: 53.86

GC content: 70.11

Gene sequence:

>930_bases
GTGATTGATGGGCACGCGGATTCGATCCTGATGGTCCTGGCCGGCGAGCGCACCCTGACCGAACGGTCGGACAAGGGGCA
CATCGACTGGCCCCGGGCCCGGGAGGCCGGGGTCACCTGCACGGTGCAGGCGGCCTGGGTCGACCCGGTCTACTACCCCG
TGGCCCCGCGGCGGGCGCACGAGGCCATCGACGGGCTGCTGGGCCAGATCGACGCGGCCGAAGGCGTGCGGCTGGTGCTG
CGGGCCGACGACGTCACCGCCGCCCACGCGGCCGGCGAACTGGCCGTGCTGCTGAACATCGAGGGGGCGGAGGCGATCCA
GGGGTCCCTGGCCCTGCTGCGCAACTACTACCGGCTGGGCGTGCGCATGATGGGCCTCGTCTGGAACCACCGCAACGAGG
TGGCCGAAGGGGTCGGCGAACCCGAGTCCGGCGGCGGCCTCACCCGGTTCGGTCGCGAGGTGGTGCGCGAGATGAACCGG
TTGGGCATGCTCATCGACCTGGCCCACATCACGCCGGCAGGGTTCTTCCAGGTGCTGGAACTGTCGGAGGACCCGGTGCT
GTTCACCCACGGCAACTGCCAGGCGCTGTACGATCACCCCCGGAACCTGACCGATGAGCAGATCCGGGCCCTGGCCGCGC
ACGGCGGCGTGTTCGGCATCTCCTTCGTGTCCAGCTTTATGGGCCGGGAGACCGCAGCCTTGACGACGGTGGCCGATCAC
ATCGACCACGTGTGCCAGTTGCTGGGCAATGCCGACCACGTCGGCCTGGGCTCGGACTTCGACGGGGCGACGCCGCCGCC
CGGGCTGGAGGACGTCACCTGCCTGCCCCGGTTGACGGCGGAGCTCATGCGGCGGGGGTACGGGGAGGCCGACCTGGTCA
AGATCCTGGGCGGCAACTACTTGCGGGTCTTCCAACAGGTTCTGCGGTAG

Upstream 100 bases:

>100_bases
CGCCCATCGAAATGGAAACACTCCTAACGGCAACGCGCTCGGGAGGGAGTCGCAGATGGTGCACCTGGAGGAGGCAGCGG
CGCTGCACCGCCGCTGCCCG

Downstream 100 bases:

>100_bases
CGGTTCCGGCGCGGTGGCTCGATTCAGGGAAGGAGGCGTCACACATGAAGGTCGAGGTAACCAGCCAGGCTCTCACCGAA
GTCGCCGTGGACGTGCTGAT

Product: putative dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIDGHADSILMVLAGERTLTERSDKGHIDWPRAREAGVTCTVQAAWVDPVYYPVAPRRAHEAIDGLLGQIDAAEGVRLVL
RADDVTAAHAAGELAVLLNIEGAEAIQGSLALLRNYYRLGVRMMGLVWNHRNEVAEGVGEPESGGGLTRFGREVVREMNR
LGMLIDLAHITPAGFFQVLELSEDPVLFTHGNCQALYDHPRNLTDEQIRALAAHGGVFGISFVSSFMGRETAALTTVADH
IDHVCQLLGNADHVGLGSDFDGATPPPGLEDVTCLPRLTAELMRRGYGEADLVKILGGNYLRVFQQVLR

Sequences:

>Translated_309_residues
MIDGHADSILMVLAGERTLTERSDKGHIDWPRAREAGVTCTVQAAWVDPVYYPVAPRRAHEAIDGLLGQIDAAEGVRLVL
RADDVTAAHAAGELAVLLNIEGAEAIQGSLALLRNYYRLGVRMMGLVWNHRNEVAEGVGEPESGGGLTRFGREVVREMNR
LGMLIDLAHITPAGFFQVLELSEDPVLFTHGNCQALYDHPRNLTDEQIRALAAHGGVFGISFVSSFMGRETAALTTVADH
IDHVCQLLGNADHVGLGSDFDGATPPPGLEDVTCLPRLTAELMRRGYGEADLVKILGGNYLRVFQQVLR
>Mature_309_residues
MIDGHADSILMVLAGERTLTERSDKGHIDWPRAREAGVTCTVQAAWVDPVYYPVAPRRAHEAIDGLLGQIDAAEGVRLVL
RADDVTAAHAAGELAVLLNIEGAEAIQGSLALLRNYYRLGVRMMGLVWNHRNEVAEGVGEPESGGGLTRFGREVVREMNR
LGMLIDLAHITPAGFFQVLELSEDPVLFTHGNCQALYDHPRNLTDEQIRALAAHGGVFGISFVSSFMGRETAALTTVADH
IDHVCQLLGNADHVGLGSDFDGATPPPGLEDVTCLPRLTAELMRRGYGEADLVKILGGNYLRVFQQVLR

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=233, Percent_Identity=39.4849785407725, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI189458885, Length=330, Percent_Identity=34.2424242424242, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI4758190, Length=330, Percent_Identity=34.2424242424242, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI193211608, Length=280, Percent_Identity=34.2857142857143, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI193211610, Length=280, Percent_Identity=34.6428571428571, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI221475880, Length=304, Percent_Identity=36.5131578947368, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281362638, Length=298, Percent_Identity=33.5570469798658, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281362636, Length=298, Percent_Identity=33.5570469798658, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161083233, Length=306, Percent_Identity=35.6209150326797, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21356391, Length=298, Percent_Identity=27.8523489932886, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 33507; Mature: 33507

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGHADSILMVLAGERTLTERSDKGHIDWPRAREAGVTCTVQAAWVDPVYYPVAPRRAH
CCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCHHCCCEEEEEEEEECCEECCCCCHHHH
EAIDGLLGQIDAAEGVRLVLRADDVTAAHAAGELAVLLNIEGAEAIQGSLALLRNYYRLG
HHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
VRMMGLVWNHRNEVAEGVGEPESGGGLTRFGREVVREMNRLGMLIDLAHITPAGFFQVLE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
LSEDPVLFTHGNCQALYDHPRNLTDEQIRALAAHGGVFGISFVSSFMGRETAALTTVADH
CCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
IDHVCQLLGNADHVGLGSDFDGATPPPGLEDVTCLPRLTAELMRRGYGEADLVKILGGNY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCH
LRVFQQVLR
HHHHHHHHC
>Mature Secondary Structure
MIDGHADSILMVLAGERTLTERSDKGHIDWPRAREAGVTCTVQAAWVDPVYYPVAPRRAH
CCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCHHCCCEEEEEEEEECCEECCCCCHHHH
EAIDGLLGQIDAAEGVRLVLRADDVTAAHAAGELAVLLNIEGAEAIQGSLALLRNYYRLG
HHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
VRMMGLVWNHRNEVAEGVGEPESGGGLTRFGREVVREMNRLGMLIDLAHITPAGFFQVLE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
LSEDPVLFTHGNCQALYDHPRNLTDEQIRALAAHGGVFGISFVSSFMGRETAALTTVADH
CCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHH
IDHVCQLLGNADHVGLGSDFDGATPPPGLEDVTCLPRLTAELMRRGYGEADLVKILGGNY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCH
LRVFQQVLR
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]