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The map label for this gene is ywaC [H]

Identifier: 51892774

GI number: 51892774

Start: 1779771

End: 1780985

Strand: Reverse

Name: ywaC [H]

Synonym: STH1636

Alternate gene names: 51892774

Gene position: 1780985-1779771 (Counterclockwise)

Preceding gene: 51892777

Following gene: 51892764

Centisome position: 49.94

GC content: 67.57

Gene sequence:

>1215_bases
GTGTCTTTCCCTCTACCCTCGCGGTCCATCCGGGACCGCTCCCTTTTTGCGCGCAGGAGATTCCGTCGCCGTCAGGGAAG
GAATGGGCCGGTGCACATCGGCTGCGCAAACGAGGTGATGCAGCTCATGAACGGCAAGCAGCGTGAGTGGGTAGAGACGT
TCCGGTCGCAGCAGGCTCTGTACCAGGCCTTCGGCCAGTGTGTGCAGCAACTCCTCAGCCACCTGCTGGACGAGGCCAAC
ATCCCGATCAACGGCATCACCTACCGGGTCAAGAGCGTCGACGCGCTGGCGGAGAAGCTGACTCGCCCGGGCAAGGACTA
CGAGTCCCTCATCGAGGTGACGGACCTGGTGGGCGTGCGGGTCGTCACCAACTTCGCCGACGACGTCGACCGGGTCGTGC
GGGTGATCGACCGCCACTTCGAGGTGGATCTGGACCATTCCGAGGACAAACGCCCCCACGACCCGCACTGGTTCGGCTAC
TCCTCGGTCCACCGGGTCTGCCTCCTGCCCCCGGCGGTGCTGGCCAGGCCCGAGTACGCTCGCTTTGCCGGGCTGCGCTG
CGAGATCCAGGTTCGCTCGATTCTCCAGCACGCCTGGGCGGAGATCGAGCACGACCTGGGGTACAAGGTCGCGGGAGGCA
TCCCCAGCAGCCTGCGGCGCCGGTTCTCCATGCTGGCCGGCCTGCTGGAGCTGGCCGACGACCAGTTCATGCGGTTGCGC
GATGAGCTTAGCCTGTACTCGACCCGGGTGGTGGCCCAGATGCACGATCACCCGGAGAGCGTGGCGCTGGACCCGATCTC
GCTGGAGACCTTCATCCGGCGCTCCGACCTCGTCCAGGCCCTGGATGAGGAGATCTCCGAGATGCGGGGCCGGCCCCTGA
TGGGACCGACCAAGGCGGTGCTGGAGGCCCGTGTGGAGGAGCTGGAGCACCTGGGCATCACCAACCTGAAGGACCTGGCG
GATGCCCTCGAGCAGTCGCAGGAACGGGTCCGGTCGCTGGCGCGGCAGATCTACCGGGACGACCGGCGGCGGGGCCTGCC
CATGTCGCGGGGCAGCTGCCTGAGCCTCCTGGTGCAGGTCCTCATCGGGCGCCGGGAGAGCCTGGACGAGATCCGGGCCC
TGCTGGACCGCTTCAACATCGGCGCACCTGCCGCCAGGGACGAACGGGCGCTGCTCCTGAGGTCCATGGCACAGGGGTTG
CCGGCCAAGCGGTAG

Upstream 100 bases:

>100_bases
ACGGCTGGATCGTTTCCCTGGTCTCCTCCTGGCCGTTGCGGACTTGTTACAACGTTGTAACATTCCCGCTGTATACTGAA
AGTGTGTTGAACCCCCCTCT

Downstream 100 bases:

>100_bases
CCCCGCCCCTCCATCGACAGAAAAGGCGGCGAGCGGCTGTCCGCTCGCCGTTTTCGTCTCGCCGTCCGGCGCCCTCTGAG
TCACAGAGCGATGCGGGACA

Product: putative GTP pyrophosphokinase

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2 [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSFPLPSRSIRDRSLFARRRFRRRQGRNGPVHIGCANEVMQLMNGKQREWVETFRSQQALYQAFGQCVQQLLSHLLDEAN
IPINGITYRVKSVDALAEKLTRPGKDYESLIEVTDLVGVRVVTNFADDVDRVVRVIDRHFEVDLDHSEDKRPHDPHWFGY
SSVHRVCLLPPAVLARPEYARFAGLRCEIQVRSILQHAWAEIEHDLGYKVAGGIPSSLRRRFSMLAGLLELADDQFMRLR
DELSLYSTRVVAQMHDHPESVALDPISLETFIRRSDLVQALDEEISEMRGRPLMGPTKAVLEARVEELEHLGITNLKDLA
DALEQSQERVRSLARQIYRDDRRRGLPMSRGSCLSLLVQVLIGRRESLDEIRALLDRFNIGAPAARDERALLLRSMAQGL
PAKR

Sequences:

>Translated_404_residues
MSFPLPSRSIRDRSLFARRRFRRRQGRNGPVHIGCANEVMQLMNGKQREWVETFRSQQALYQAFGQCVQQLLSHLLDEAN
IPINGITYRVKSVDALAEKLTRPGKDYESLIEVTDLVGVRVVTNFADDVDRVVRVIDRHFEVDLDHSEDKRPHDPHWFGY
SSVHRVCLLPPAVLARPEYARFAGLRCEIQVRSILQHAWAEIEHDLGYKVAGGIPSSLRRRFSMLAGLLELADDQFMRLR
DELSLYSTRVVAQMHDHPESVALDPISLETFIRRSDLVQALDEEISEMRGRPLMGPTKAVLEARVEELEHLGITNLKDLA
DALEQSQERVRSLARQIYRDDRRRGLPMSRGSCLSLLVQVLIGRRESLDEIRALLDRFNIGAPAARDERALLLRSMAQGL
PAKR
>Mature_403_residues
SFPLPSRSIRDRSLFARRRFRRRQGRNGPVHIGCANEVMQLMNGKQREWVETFRSQQALYQAFGQCVQQLLSHLLDEANI
PINGITYRVKSVDALAEKLTRPGKDYESLIEVTDLVGVRVVTNFADDVDRVVRVIDRHFEVDLDHSEDKRPHDPHWFGYS
SVHRVCLLPPAVLARPEYARFAGLRCEIQVRSILQHAWAEIEHDLGYKVAGGIPSSLRRRFSMLAGLLELADDQFMRLRD
ELSLYSTRVVAQMHDHPESVALDPISLETFIRRSDLVQALDEEISEMRGRPLMGPTKAVLEARVEELEHLGITNLKDLAD
ALEQSQERVRSLARQIYRDDRRRGLPMSRGSCLSLLVQVLIGRRESLDEIRALLDRFNIGAPAARDERALLLRSMAQGLP
AKR

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 46224; Mature: 46093

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPLPSRSIRDRSLFARRRFRRRQGRNGPVHIGCANEVMQLMNGKQREWVETFRSQQAL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHH
YQAFGQCVQQLLSHLLDEANIPINGITYRVKSVDALAEKLTRPGKDYESLIEVTDLVGVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVTNFADDVDRVVRVIDRHFEVDLDHSEDKRPHDPHWFGYSSVHRVCLLPPAVLARPEYA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCHH
RFAGLRCEIQVRSILQHAWAEIEHDLGYKVAGGIPSSLRRRFSMLAGLLELADDQFMRLR
HHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DELSLYSTRVVAQMHDHPESVALDPISLETFIRRSDLVQALDEEISEMRGRPLMGPTKAV
HHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LEARVEELEHLGITNLKDLADALEQSQERVRSLARQIYRDDRRRGLPMSRGSCLSLLVQV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LIGRRESLDEIRALLDRFNIGAPAARDERALLLRSMAQGLPAKR
HHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SFPLPSRSIRDRSLFARRRFRRRQGRNGPVHIGCANEVMQLMNGKQREWVETFRSQQAL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHH
YQAFGQCVQQLLSHLLDEANIPINGITYRVKSVDALAEKLTRPGKDYESLIEVTDLVGVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVTNFADDVDRVVRVIDRHFEVDLDHSEDKRPHDPHWFGYSSVHRVCLLPPAVLARPEYA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCHH
RFAGLRCEIQVRSILQHAWAEIEHDLGYKVAGGIPSSLRRRFSMLAGLLELADDQFMRLR
HHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DELSLYSTRVVAQMHDHPESVALDPISLETFIRRSDLVQALDEEISEMRGRPLMGPTKAV
HHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LEARVEELEHLGITNLKDLADALEQSQERVRSLARQIYRDDRRRGLPMSRGSCLSLLVQV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LIGRRESLDEIRALLDRFNIGAPAARDERALLLRSMAQGLPAKR
HHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]