Click here to switch to the map view.

The map label for this gene is nreB [H]

Identifier: 51892160

GI number: 51892160

Start: 1136060

End: 1137223

Strand: Reverse

Name: nreB [H]

Synonym: STH1022

Alternate gene names: 51892160

Gene position: 1137223-1136060 (Counterclockwise)

Preceding gene: 51892162

Following gene: 51892158

Centisome position: 31.89

GC content: 73.54

Gene sequence:

>1164_bases
ATGCGCTGGTCCGACGTTCCGGTGGAGAACAAGGCGCAGATCGCCTGGGGTGCGCTGGTGGTCGTCTACCTGCTCGGGGC
CCAGCGGCCCGAGCTCATCCGGCCGCCGGTGGTGGCCGTCTTCCTGCTGTCGGCCGCCGCCGCCTTCCTGGAACTCTGGC
TGCGCAGCCGGGGCTGGCCGCACCTCCTCTGGTACGACTGCATCGTCTGGTCCGCGCTGCTGACCGGGATGGTGGTGGTC
ACCGGCGGGCGGGGCTCCGAGGTCTGGGCCGCCTACATCCTCATGTCGCTCACGGCGCCGGTGGTGCTCCGGCGGGTGGC
GCCGTACATCCTGCTGGGGGTCAACGTCACCGCCTACGGGCTGATCTACCTCCTCTACAACCCCTTTGGGGCCCCGCTGG
ACTGGGGCCTGCTCTTCCTGCGCATCGGGACCATCTTCCTGGTGGCCTACGTGGTCGACCGCTCCACCGCCCGGGAGCGG
CAGTCCCACGCGCGGGCGGTGGCGCTGGCCCGCAGCCGGGTCAGCGAGCTGGTCCAGGCCCGGGACGCCGAGCGGCGGCG
CATCGCCCACGACATCCACGACTGGCTGGGCACCGGAATCATCGCGCCGCTCCGGCGACTGGAGATCGCCGCCCGCCAGT
CCGACGTGGAGAGCTGCCGGCGGCACGTGGAAGAGGCCGCCGACTCGCTCCGGCGGGCCCACGCCGAGCTCAGGCGGCTG
ATGGAGAACCTGCACCCCCACCTCCTGGAGCAGATGGGGCTGGCGGAGGCGCTGCGGGCGTACCTCACCGACTGGGGCGA
GGAGCACGGCGTGGCCGTGCACTACCACCTCACGCCCGGCCCCGAGCCGCCGGCGGACGCGGCGCTGGCGCTGTACCGCA
TCCAGCAGGAGGCGCTCAACAACTGCGCCAAGCACGCCGACGCCAGCCAGGTCTGGGTGACGCTGGAGCTGGGCGCGGAC
CGGGTGCGGCTGACGCTGCGGGACGACGGACACGGCCGGCCCGGCCGCCCGGGCCGGGGCATCACGGGGATGCAGGAGCG
CGCCGCCGCCTTCGGCGGCACGGTGACGGTCCACGGTCAGCCGGGCCGGGGCACGACCGTCACCGCCGAACTGCCGCTCA
GGGCGGCTGCAGCAGCGGCTCCAGCGCCGACAGAACCGTTCTGA

Upstream 100 bases:

>100_bases
CCCGCTGCCTGCCCGCTGAGGCGCGCGTGCGCCTGTCATGCGAATCGCTGTAGAATAGCGTTGAACAGCATCATATTAAC
ACAAGGAGGAAAGCCAGACC

Downstream 100 bases:

>100_bases
CCACGATGGCGTACCCCTGCGCGGTGGGATGGATGCCGTCGCGCTGGTTCAGGTAGGGCGACCCCGCCACCCCCTCCAGG
AAGAAGGGGATGAGGGGGAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRWSDVPVENKAQIAWGALVVVYLLGAQRPELIRPPVVAVFLLSAAAAFLELWLRSRGWPHLLWYDCIVWSALLTGMVVV
TGGRGSEVWAAYILMSLTAPVVLRRVAPYILLGVNVTAYGLIYLLYNPFGAPLDWGLLFLRIGTIFLVAYVVDRSTARER
QSHARAVALARSRVSELVQARDAERRRIAHDIHDWLGTGIIAPLRRLEIAARQSDVESCRRHVEEAADSLRRAHAELRRL
MENLHPHLLEQMGLAEALRAYLTDWGEEHGVAVHYHLTPGPEPPADAALALYRIQQEALNNCAKHADASQVWVTLELGAD
RVRLTLRDDGHGRPGRPGRGITGMQERAAAFGGTVTVHGQPGRGTTVTAELPLRAAAAAAPAPTEPF

Sequences:

>Translated_387_residues
MRWSDVPVENKAQIAWGALVVVYLLGAQRPELIRPPVVAVFLLSAAAAFLELWLRSRGWPHLLWYDCIVWSALLTGMVVV
TGGRGSEVWAAYILMSLTAPVVLRRVAPYILLGVNVTAYGLIYLLYNPFGAPLDWGLLFLRIGTIFLVAYVVDRSTARER
QSHARAVALARSRVSELVQARDAERRRIAHDIHDWLGTGIIAPLRRLEIAARQSDVESCRRHVEEAADSLRRAHAELRRL
MENLHPHLLEQMGLAEALRAYLTDWGEEHGVAVHYHLTPGPEPPADAALALYRIQQEALNNCAKHADASQVWVTLELGAD
RVRLTLRDDGHGRPGRPGRGITGMQERAAAFGGTVTVHGQPGRGTTVTAELPLRAAAAAAPAPTEPF
>Mature_387_residues
MRWSDVPVENKAQIAWGALVVVYLLGAQRPELIRPPVVAVFLLSAAAAFLELWLRSRGWPHLLWYDCIVWSALLTGMVVV
TGGRGSEVWAAYILMSLTAPVVLRRVAPYILLGVNVTAYGLIYLLYNPFGAPLDWGLLFLRIGTIFLVAYVVDRSTARER
QSHARAVALARSRVSELVQARDAERRRIAHDIHDWLGTGIIAPLRRLEIAARQSDVESCRRHVEEAADSLRRAHAELRRL
MENLHPHLLEQMGLAEALRAYLTDWGEEHGVAVHYHLTPGPEPPADAALALYRIQQEALNNCAKHADASQVWVTLELGAD
RVRLTLRDDGHGRPGRPGRGITGMQERAAAFGGTVTVHGQPGRGTTVTAELPLRAAAAAAPAPTEPF

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=225, Percent_Identity=32, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787474, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42640; Mature: 42640

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWSDVPVENKAQIAWGALVVVYLLGAQRPELIRPPVVAVFLLSAAAAFLELWLRSRGWP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
HLLWYDCIVWSALLTGMVVVTGGRGSEVWAAYILMSLTAPVVLRRVAPYILLGVNVTAYG
HHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
LIYLLYNPFGAPLDWGLLFLRIGTIFLVAYVVDRSTARERQSHARAVALARSRVSELVQA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAERRRIAHDIHDWLGTGIIAPLRRLEIAARQSDVESCRRHVEEAADSLRRAHAELRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MENLHPHLLEQMGLAEALRAYLTDWGEEHGVAVHYHLTPGPEPPADAALALYRIQQEALN
HHHHCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
NCAKHADASQVWVTLELGADRVRLTLRDDGHGRPGRPGRGITGMQERAAAFGGTVTVHGQ
HHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECC
PGRGTTVTAELPLRAAAAAAPAPTEPF
CCCCCEEEEECCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRWSDVPVENKAQIAWGALVVVYLLGAQRPELIRPPVVAVFLLSAAAAFLELWLRSRGWP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
HLLWYDCIVWSALLTGMVVVTGGRGSEVWAAYILMSLTAPVVLRRVAPYILLGVNVTAYG
HHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
LIYLLYNPFGAPLDWGLLFLRIGTIFLVAYVVDRSTARERQSHARAVALARSRVSELVQA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAERRRIAHDIHDWLGTGIIAPLRRLEIAARQSDVESCRRHVEEAADSLRRAHAELRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MENLHPHLLEQMGLAEALRAYLTDWGEEHGVAVHYHLTPGPEPPADAALALYRIQQEALN
HHHHCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
NCAKHADASQVWVTLELGADRVRLTLRDDGHGRPGRPGRGITGMQERAAAFGGTVTVHGQ
HHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECC
PGRGTTVTAELPLRAAAAAAPAPTEPF
CCCCCEEEEECCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]