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The map label for this gene is yuxL [H]

Identifier: 51892044

GI number: 51892044

Start: 1024049

End: 1026202

Strand: Reverse

Name: yuxL [H]

Synonym: STH906

Alternate gene names: 51892044

Gene position: 1026202-1024049 (Counterclockwise)

Preceding gene: 51892053

Following gene: 51892043

Centisome position: 28.78

GC content: 68.01

Gene sequence:

>2154_bases
GTGACCACCCGCCGCAGGCTCCAGGCCGAGGATCTGCTTGCCATCAAGCTGGCAGGCGACTGCCAGATATCCCCGGACGG
CACCCGCGTGGCCTATGTGCTGCAGGAGATCGACAAGAAGAAGAATGAGTACACCTCCAGCATCTGGCTGGCCCGGGAGG
GCTCCCCGCCGGTGCGCTTCACCGCCGGACCCAGGGACACGCAGCCGCGATGGTCTCCCGACGGCCGGCACCTGGTGTTC
GTCTCCAATCGCAGCGGATCGAACCAGCTGTGGCTTCTGTCCATGGAGGGGGGCGAGGCCAGGCAGATCACCCGGATCAA
GGGCGGGGTCCAGAACCCGGTGTGGAGCCCGGACGGCCGCACCATCGCCTTCACGGCAAACCTGACCGAGGCTGGCATTC
AACCGGAGGGTGGCGACGAGGACGACCAGGACCTATACCGGAAGTACACCAAGGACGTTCGCGTGATCACGCGGCTGCAC
TACAAGATGGACGGCGTGGGATTCTACACCGACGAGCGCAAGCACATCTGCGTGGTCGACGTAGACGGAGGAGAGCCGCG
GCAGCTGACCTTCGGCGACTTCAACCACCTGGACGTCAGCTGGACCCCCGACGGTCGCGGGCTGGTCTTCGCCGCCAACC
GGCGGGAGGACCGGGATTGGTATCCGGGCCACGTGGACCTGTGGTATCTGTCCCTGAGTGACGACGGGCAGGGACAGCGG
TCCTCGGCGTACACGCCGCCTGAGGGCCCGGGCCCCGATCGATGCGAGGCTGCGGAGGAGACTCAGGGCAACTGCATGCC
CGTCCGTCTCACGCCGGGTGACGGCACGCTCGCCTGCAGTTCCCCCTCCGCCTCTCCCGACGGACGCATGATCGCCTTCC
TGGCCAGCGATCCCGCCGAATCAGGCTACGGCCTCACCGGCCTTTACGTGCTGGATCGGTCGAGCGGGGAGATCCGTCAG
CTCGCAACCGACCTGGACCGCCCCTTCGGCAACGAAACGACCGGAGATCTGGTTCCGCCCTCGGGCGGCCGGCTCCACTG
GTCGCCGGACGCACGCTGGATCTACGCCACCGTCTCCGACGGCGGTCAGGTGCAGCTGGTCCGGGTCGACGCGGTGACGG
GGGAGGTATGGCCCGTGACCGGCGGCGACCGGGTCGTCTACGCGTTCTCCCTGACGCCGGACTGCTGCAGGGCCGCCCTG
GCCTACGCGACGCCGCTCTCCCCCGGTGACGTGTACCTGGCGCAGCTGGACGAGCCACAGCCTGTCCCGCCGGTGTCGTC
GGCGGGCACGGTGCTGCGCGGCGGCGGCGTGCGGGAGGTACGGCTGACAGACCACAACGCCGAACTCTTCGCCGAGCTGG
AACTGACGGTTCCCGAGCGGTTCCAGGTGTCCGCCGGGGAGGGCGAGCCCCTCGTCGACGCCTGGATCCTACCGCCCGTG
GGACGGGAGGAGGGCAAGAAGTACCCCGCGGTGCTGGAGATTCACGGCGGACCCATGGCCATGTACGGCGCCGGGTTCTT
CTTCGAGTTCCACTGGCTGGCCGCGCAGGGGTACGCGGTGGTCTACTCCAACCCCCGGGGATCGCAGGGGTATGGACACG
ACTTCTGCCGTGTGATCCGGGCCGACTGGGGCAACCGGGATTACGCCGACGTCATGGCCGCCATCGAGGGCGCGGTGGAG
CGGTTCCCCTACGTGGACGGCGATCGCCTGGGCGTCGCCGGCGGGTCCTACGGCGGATTCATGGTCAACTGGATCGTGAG
CCACACGGACCGCTTCCGGGCGGCGGTCACGATGCGCTCCGTCGTCAACCGCTGGTCGGCGATGGGCACGTCCGACCTGG
GCTACGACCGGCTGCGCCAGTTCGGCGTCGAGAACTGGTGGGAAGTGGACAACCTGGGGCCGTTCCTTAAGCAGTCGCCG
CTGGTCCACGCCTCGCGCATCAACACCCCGCTGCTCATCGAGCATCAGGAGAACGACATGCGCTGCCCCATCGACCAGGC
CGAGCAGCTGTACGCGGCGCTGAAGTACCAGCGCAAGACGGTGAAGTTTGTGCGGTACCCTGGCGAGTCCCACGGCATGA
GCCGCACGGGCAAGCCTTGGCACCGGGTCCACAGGCTGCGGATGATCGCAGAGTGGTTTGCGGAGTATCTGTAG

Upstream 100 bases:

>100_bases
GCGCCGCAGCAGCATACCGTATGAGCCGAGCCCCGGGGAGGAATCCCGCTCCTGCCCGCCAAACTGTTAACGAAACGAAT
TATTGCGAGGGGGAGTGTGC

Downstream 100 bases:

>100_bases
GGCAGAACACCCCCGGCCGGACACCTCCGGCCGGGGGGTGGCGTTTCGGAGCCCGGACCCGGGCACTGGGGAAAGTCGCA
GATCGTGGGAAGGAAGGCCT

Product: acylaminoacyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MTTRRRLQAEDLLAIKLAGDCQISPDGTRVAYVLQEIDKKKNEYTSSIWLAREGSPPVRFTAGPRDTQPRWSPDGRHLVF
VSNRSGSNQLWLLSMEGGEARQITRIKGGVQNPVWSPDGRTIAFTANLTEAGIQPEGGDEDDQDLYRKYTKDVRVITRLH
YKMDGVGFYTDERKHICVVDVDGGEPRQLTFGDFNHLDVSWTPDGRGLVFAANRREDRDWYPGHVDLWYLSLSDDGQGQR
SSAYTPPEGPGPDRCEAAEETQGNCMPVRLTPGDGTLACSSPSASPDGRMIAFLASDPAESGYGLTGLYVLDRSSGEIRQ
LATDLDRPFGNETTGDLVPPSGGRLHWSPDARWIYATVSDGGQVQLVRVDAVTGEVWPVTGGDRVVYAFSLTPDCCRAAL
AYATPLSPGDVYLAQLDEPQPVPPVSSAGTVLRGGGVREVRLTDHNAELFAELELTVPERFQVSAGEGEPLVDAWILPPV
GREEGKKYPAVLEIHGGPMAMYGAGFFFEFHWLAAQGYAVVYSNPRGSQGYGHDFCRVIRADWGNRDYADVMAAIEGAVE
RFPYVDGDRLGVAGGSYGGFMVNWIVSHTDRFRAAVTMRSVVNRWSAMGTSDLGYDRLRQFGVENWWEVDNLGPFLKQSP
LVHASRINTPLLIEHQENDMRCPIDQAEQLYAALKYQRKTVKFVRYPGESHGMSRTGKPWHRVHRLRMIAEWFAEYL

Sequences:

>Translated_717_residues
MTTRRRLQAEDLLAIKLAGDCQISPDGTRVAYVLQEIDKKKNEYTSSIWLAREGSPPVRFTAGPRDTQPRWSPDGRHLVF
VSNRSGSNQLWLLSMEGGEARQITRIKGGVQNPVWSPDGRTIAFTANLTEAGIQPEGGDEDDQDLYRKYTKDVRVITRLH
YKMDGVGFYTDERKHICVVDVDGGEPRQLTFGDFNHLDVSWTPDGRGLVFAANRREDRDWYPGHVDLWYLSLSDDGQGQR
SSAYTPPEGPGPDRCEAAEETQGNCMPVRLTPGDGTLACSSPSASPDGRMIAFLASDPAESGYGLTGLYVLDRSSGEIRQ
LATDLDRPFGNETTGDLVPPSGGRLHWSPDARWIYATVSDGGQVQLVRVDAVTGEVWPVTGGDRVVYAFSLTPDCCRAAL
AYATPLSPGDVYLAQLDEPQPVPPVSSAGTVLRGGGVREVRLTDHNAELFAELELTVPERFQVSAGEGEPLVDAWILPPV
GREEGKKYPAVLEIHGGPMAMYGAGFFFEFHWLAAQGYAVVYSNPRGSQGYGHDFCRVIRADWGNRDYADVMAAIEGAVE
RFPYVDGDRLGVAGGSYGGFMVNWIVSHTDRFRAAVTMRSVVNRWSAMGTSDLGYDRLRQFGVENWWEVDNLGPFLKQSP
LVHASRINTPLLIEHQENDMRCPIDQAEQLYAALKYQRKTVKFVRYPGESHGMSRTGKPWHRVHRLRMIAEWFAEYL
>Mature_716_residues
TTRRRLQAEDLLAIKLAGDCQISPDGTRVAYVLQEIDKKKNEYTSSIWLAREGSPPVRFTAGPRDTQPRWSPDGRHLVFV
SNRSGSNQLWLLSMEGGEARQITRIKGGVQNPVWSPDGRTIAFTANLTEAGIQPEGGDEDDQDLYRKYTKDVRVITRLHY
KMDGVGFYTDERKHICVVDVDGGEPRQLTFGDFNHLDVSWTPDGRGLVFAANRREDRDWYPGHVDLWYLSLSDDGQGQRS
SAYTPPEGPGPDRCEAAEETQGNCMPVRLTPGDGTLACSSPSASPDGRMIAFLASDPAESGYGLTGLYVLDRSSGEIRQL
ATDLDRPFGNETTGDLVPPSGGRLHWSPDARWIYATVSDGGQVQLVRVDAVTGEVWPVTGGDRVVYAFSLTPDCCRAALA
YATPLSPGDVYLAQLDEPQPVPPVSSAGTVLRGGGVREVRLTDHNAELFAELELTVPERFQVSAGEGEPLVDAWILPPVG
REEGKKYPAVLEIHGGPMAMYGAGFFFEFHWLAAQGYAVVYSNPRGSQGYGHDFCRVIRADWGNRDYADVMAAIEGAVER
FPYVDGDRLGVAGGSYGGFMVNWIVSHTDRFRAAVTMRSVVNRWSAMGTSDLGYDRLRQFGVENWWEVDNLGPFLKQSPL
VHASRINTPLLIEHQENDMRCPIDQAEQLYAALKYQRKTVKFVRYPGESHGMSRTGKPWHRVHRLRMIAEWFAEYL

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=448, Percent_Identity=24.7767857142857, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI37577089, Length=219, Percent_Identity=26.9406392694064, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI18450280, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25149159, Length=373, Percent_Identity=24.9329758713137, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144540, Length=211, Percent_Identity=28.9099526066351, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144537, Length=211, Percent_Identity=28.9099526066351, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17552908, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551969, Length=247, Percent_Identity=27.5303643724696, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550825, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553511, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 79618; Mature: 79487

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRRRLQAEDLLAIKLAGDCQISPDGTRVAYVLQEIDKKKNEYTSSIWLAREGSPPVRF
CCCCHHCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
TAGPRDTQPRWSPDGRHLVFVSNRSGSNQLWLLSMEGGEARQITRIKGGVQNPVWSPDGR
ECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCCCCCCC
TIAFTANLTEAGIQPEGGDEDDQDLYRKYTKDVRVITRLHYKMDGVGFYTDERKHICVVD
EEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEECCCCEEEEEE
VDGGEPRQLTFGDFNHLDVSWTPDGRGLVFAANRREDRDWYPGHVDLWYLSLSDDGQGQR
CCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCC
SSAYTPPEGPGPDRCEAAEETQGNCMPVRLTPGDGTLACSSPSASPDGRMIAFLASDPAE
CCCCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCEEEEEECCCCC
SGYGLTGLYVLDRSSGEIRQLATDLDRPFGNETTGDLVPPSGGRLHWSPDARWIYATVSD
CCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECC
GGQVQLVRVDAVTGEVWPVTGGDRVVYAFSLTPDCCRAALAYATPLSPGDVYLAQLDEPQ
CCEEEEEEEEEECCEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCCC
PVPPVSSAGTVLRGGGVREVRLTDHNAELFAELELTVPERFQVSAGEGEPLVDAWILPPV
CCCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCC
GREEGKKYPAVLEIHGGPMAMYGAGFFFEFHWLAAQGYAVVYSNPRGSQGYGHDFCRVIR
CHHCCCCCCEEEEECCCCEEEECCCEEEEEEEEEECCEEEEECCCCCCCCCCHHHHHHHH
ADWGNRDYADVMAAIEGAVERFPYVDGDRLGVAGGSYGGFMVNWIVSHTDRFRAAVTMRS
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEHHCCHHHHHHHHHHH
VVNRWSAMGTSDLGYDRLRQFGVENWWEVDNLGPFLKQSPLVHASRINTPLLIEHQENDM
HHHHHHHCCCCCCCHHHHHHCCCCCCEECCCCCHHHHCCCCEEHHHCCCCEEEEECCCCC
RCPIDQAEQLYAALKYQRKTVKFVRYPGESHGMSRTGKPWHRVHRLRMIAEWFAEYL
CCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TTRRRLQAEDLLAIKLAGDCQISPDGTRVAYVLQEIDKKKNEYTSSIWLAREGSPPVRF
CCCHHCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEE
TAGPRDTQPRWSPDGRHLVFVSNRSGSNQLWLLSMEGGEARQITRIKGGVQNPVWSPDGR
ECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEHHHCCCCCCCCCCCCCC
TIAFTANLTEAGIQPEGGDEDDQDLYRKYTKDVRVITRLHYKMDGVGFYTDERKHICVVD
EEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCEEEEECCCCEEEEEE
VDGGEPRQLTFGDFNHLDVSWTPDGRGLVFAANRREDRDWYPGHVDLWYLSLSDDGQGQR
CCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCC
SSAYTPPEGPGPDRCEAAEETQGNCMPVRLTPGDGTLACSSPSASPDGRMIAFLASDPAE
CCCCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCEEEEEECCCCC
SGYGLTGLYVLDRSSGEIRQLATDLDRPFGNETTGDLVPPSGGRLHWSPDARWIYATVSD
CCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECC
GGQVQLVRVDAVTGEVWPVTGGDRVVYAFSLTPDCCRAALAYATPLSPGDVYLAQLDEPQ
CCEEEEEEEEEECCEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCCC
PVPPVSSAGTVLRGGGVREVRLTDHNAELFAELELTVPERFQVSAGEGEPLVDAWILPPV
CCCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCC
GREEGKKYPAVLEIHGGPMAMYGAGFFFEFHWLAAQGYAVVYSNPRGSQGYGHDFCRVIR
CHHCCCCCCEEEEECCCCEEEECCCEEEEEEEEEECCEEEEECCCCCCCCCCHHHHHHHH
ADWGNRDYADVMAAIEGAVERFPYVDGDRLGVAGGSYGGFMVNWIVSHTDRFRAAVTMRS
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEHHCCHHHHHHHHHHH
VVNRWSAMGTSDLGYDRLRQFGVENWWEVDNLGPFLKQSPLVHASRINTPLLIEHQENDM
HHHHHHHCCCCCCCHHHHHHCCCCCCEECCCCCHHHHCCCCEEHHHCCCCEEEEECCCCC
RCPIDQAEQLYAALKYQRKTVKFVRYPGESHGMSRTGKPWHRVHRLRMIAEWFAEYL
CCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]