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The map label for this gene is ubiE [C]

Identifier: 51892023

GI number: 51892023

Start: 996636

End: 997475

Strand: Reverse

Name: ubiE [C]

Synonym: STH885

Alternate gene names: 51892023

Gene position: 997475-996636 (Counterclockwise)

Preceding gene: 51892024

Following gene: 51892020

Centisome position: 27.97

GC content: 65.95

Gene sequence:

>840_bases
TTGCGACTGGCCACGAGGATTCTGCTTTCGCTGAACAAGCTCTTCCCCCCGCCCGTGCACCCGTTCAATTTGGCCAACCA
GGGCACGATGCGGTACGCCGACTGGCAGTTCGAGCGGGGCCATCTCACCCTGGAGCACTACCGGCCCTTCCTGTCGCCGG
AGGAGATCATGCGGGGCAAGACCGTGCTGGACATCGGCTCGGGGGCGGGCGGCAAGACCCTCTACTACGCCACCCTGGGC
GTGAAAAAGATCTACGGCGTGGACGTCGTCCCCCACTACGAGCACGAGGCCCGGGCCCTGGCGGCCGAGAAGAACCTCTC
CGACCGGGCCGAGTTCCTCACCGCCGACGCCACCGCCCTGCCCTTCCCGGACGACCACTTCGACGTGATCATCGCCAACG
ACGTCATGGAGCACGTGGCCCAGCCCGAGGCGGTGCTGCGGGAGGCGTACCGGGTGCTGAAGCCCGGGGGCCGGTTCTTC
ACCAACTTCCCTCCGTACTACCACCCCTACGGCGCCCACCTCTCGGACGTCATCGGCATCCCCTGGGTCCACGCGTTCTT
CAGCGAGCCAGTGCTGATCGAGGCATACCGGGAGTTGGTAAAGGACCTGCCGGACGCCGACATGCGGCTCCGGCTGCGGC
TCGGCAATCCCGAGACCAACCGGACCCGGATCACCTACATCAACCGCATGACGATCAAGCGGTTCCGGCGTATCGTGGAA
GAGTCGCCGTTCCGGATCGCCCACTGGCGGCTGGTGCCGCTCCGCTCCTTCTTGAAGCCCCTGGCGGCGGTGGCGCCGGA
GTTCTTCATGAAGGCTGTCGTCTGCATCCTGGAGAAGTAA

Upstream 100 bases:

>100_bases
GGGGGGCGCCGGGGCCCGTGCCGCCCCGGGCGCTGCCGAAGCAGGCGCCGTCCCCGGTGGAGGTTTCCTCCCGGCGGCGC
CGATGAGGAGTGGTGACGAC

Downstream 100 bases:

>100_bases
GTGAGGCGTTTACACCAGAAGCACAAGGGGCTGTCCCGGGCAGACGTCTCTGCTCCGGGACAGCCCCTTGCGTTTGTCCG
GCGATCCCCGAGGTGCGCCT

Product: putative methyl transferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRLATRILLSLNKLFPPPVHPFNLANQGTMRYADWQFERGHLTLEHYRPFLSPEEIMRGKTVLDIGSGAGGKTLYYATLG
VKKIYGVDVVPHYEHEARALAAEKNLSDRAEFLTADATALPFPDDHFDVIIANDVMEHVAQPEAVLREAYRVLKPGGRFF
TNFPPYYHPYGAHLSDVIGIPWVHAFFSEPVLIEAYRELVKDLPDADMRLRLRLGNPETNRTRITYINRMTIKRFRRIVE
ESPFRIAHWRLVPLRSFLKPLAAVAPEFFMKAVVCILEK

Sequences:

>Translated_279_residues
MRLATRILLSLNKLFPPPVHPFNLANQGTMRYADWQFERGHLTLEHYRPFLSPEEIMRGKTVLDIGSGAGGKTLYYATLG
VKKIYGVDVVPHYEHEARALAAEKNLSDRAEFLTADATALPFPDDHFDVIIANDVMEHVAQPEAVLREAYRVLKPGGRFF
TNFPPYYHPYGAHLSDVIGIPWVHAFFSEPVLIEAYRELVKDLPDADMRLRLRLGNPETNRTRITYINRMTIKRFRRIVE
ESPFRIAHWRLVPLRSFLKPLAAVAPEFFMKAVVCILEK
>Mature_279_residues
MRLATRILLSLNKLFPPPVHPFNLANQGTMRYADWQFERGHLTLEHYRPFLSPEEIMRGKTVLDIGSGAGGKTLYYATLG
VKKIYGVDVVPHYEHEARALAAEKNLSDRAEFLTADATALPFPDDHFDVIIANDVMEHVAQPEAVLREAYRVLKPGGRFF
TNFPPYYHPYGAHLSDVIGIPWVHAFFSEPVLIEAYRELVKDLPDADMRLRLRLGNPETNRTRITYINRMTIKRFRRIVE
ESPFRIAHWRLVPLRSFLKPLAAVAPEFFMKAVVCILEK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=107, Percent_Identity=34.5794392523364, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25143945, Length=105, Percent_Identity=36.1904761904762, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323635, Length=115, Percent_Identity=33.9130434782609, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32084; Mature: 32084

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLATRILLSLNKLFPPPVHPFNLANQGTMRYADWQFERGHLTLEHYRPFLSPEEIMRGK
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEECCCCEEHHHCCCCCCHHHHHCCC
TVLDIGSGAGGKTLYYATLGVKKIYGVDVVPHYEHEARALAAEKNLSDRAEFLTADATAL
EEEEECCCCCCCEEEEEEECHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCC
PFPDDHFDVIIANDVMEHVAQPEAVLREAYRVLKPGGRFFTNFPPYYHPYGAHLSDVIGI
CCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCC
PWVHAFFSEPVLIEAYRELVKDLPDADMRLRLRLGNPETNRTRITYINRMTIKRFRRIVE
HHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
ESPFRIAHWRLVPLRSFLKPLAAVAPEFFMKAVVCILEK
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLATRILLSLNKLFPPPVHPFNLANQGTMRYADWQFERGHLTLEHYRPFLSPEEIMRGK
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEECCCCEEHHHCCCCCCHHHHHCCC
TVLDIGSGAGGKTLYYATLGVKKIYGVDVVPHYEHEARALAAEKNLSDRAEFLTADATAL
EEEEECCCCCCCEEEEEEECHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCC
PFPDDHFDVIIANDVMEHVAQPEAVLREAYRVLKPGGRFFTNFPPYYHPYGAHLSDVIGI
CCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCC
PWVHAFFSEPVLIEAYRELVKDLPDADMRLRLRLGNPETNRTRITYINRMTIKRFRRIVE
HHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
ESPFRIAHWRLVPLRSFLKPLAAVAPEFFMKAVVCILEK
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA