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The map label for this gene is ypnP [H]

Identifier: 51892010

GI number: 51892010

Start: 983187

End: 984575

Strand: Reverse

Name: ypnP [H]

Synonym: STH872

Alternate gene names: 51892010

Gene position: 984575-983187 (Counterclockwise)

Preceding gene: 51892014

Following gene: 51892006

Centisome position: 27.61

GC content: 68.61

Gene sequence:

>1389_bases
ATGCGTCGCGGTTCACAGCGTGACTTCACGCAGGGCTCCATTCCCCGCCACATCATCATGTTTTCGCTGCCGCTGTTTGC
CGGCAACCTCCTCCAGATGCTCTACAACGTGGTCGACTCCATCTGGGTGGGCCAGGTGATCGGCAAGAACGCCCTCGGGG
CCGTGTCGGTCTCCCAGCCCCTGATCTTCGCCCTCATCTCCCTCGTCGTCGGCCTGACGATGGCGACGACCACGCTGGTG
GGCCAGTACCGGGGCGCCGGGAAGGAAGAGCTGGTGCAGCGGACCATCGGCACCTCGCTGATCCTGCTGGCGGGCCTCGG
CGCGGTGGTGGGGGTGCTGGGCGTCCTCCTCCGCTACCCGCTCCTCCGGATGATCGACACGCCGGAGGAGATCATCCACG
ATGCCGCCGCCTACCTGGCCATCTTCATGGGAGGCATCCTGTTCCTCTTCCTGTACAACACCCTCGGGGCCATCCTCCGG
GGCCTGGGCGACGCCAACACGCCACTGATCGCCCTGGCGATCGCGACGGTCCTCAACATCATCCTGGACGGCATCTTCAT
CCTGGGGCTGGGTCCTGTTCCCCCGATGGGTGTCCCGGGCGTGGCCATCGCGACGGTGGTGGCCCAGGGCATCAGCGCCA
TCTGGCTGGCCCGCTGGATCCTGAAGAAGACGGACCTGATCCGGCTCAGCCGGGACTATTGGCGGGTGGACTGGGGGCTG
GCCGGGCGCATCTTCCGGATCGGCCTGCCTGCCGGGCTGCAGCAGGCGGTGGTCTCCTTCGGCATGGTGACGGTGACGGC
CCTGATCAACAGCTACGGGCCGGACGTCGTGGCTGCCTTCGGCGCGGCCCAGCGGCTGGACCAGGCGGCCTTCCTCCCGT
CGATGTCGATGGGTCTGGCGGTTACCTCGGTGGTGGCGCAGAACCTGGGCGCGGGGAAGCTGGACCGGGTCTCGGCCGCG
GTCCGCTGGTGCGCCGGCCTGGGCGTGGCCATCACCGGCCTGGTGACGCTGGTGGCGGTCCTGAAGCCGACGATCCTGAT
CGCCCTGTTCAACCGGGAGCCCGACGTGCTGGCCGCCGGCAGCCTCTACCTGCGGATCAACGGCTGGAGCTACATCTTCT
TCGCGCTGGTGTTCGTGCTGGGCGGCGTGATGCGCGGCGCCGGCGACACCATGGCCACGCTGGTGCTCACGATCATCGGC
CTGTGGGTGGTGCGGGTGCCCGCCGCCTACCTGCTGGCCCGCTCCTTCGGGATGGGACCGGCCGGCATCTGGACGGGCAT
CCTGATCTCCGCGATCGCCTCCTTCCTGCTGCACCTGGCGTACTACTCCACCGGCCGCTGGAAGCGGAAGGTGCCGTCCG
TCGAGCCGGCAGTGGCCGAGCGGACGTAG

Upstream 100 bases:

>100_bases
CCCGGTGGCTGGACTTCTGTCTCCTCCACTCTATGGGTGGCTGCGGGGGAAGGTCCTGCACGACGCCCGCACCGGCAGAC
TTTGGCAAAGGAGGCGCACC

Downstream 100 bases:

>100_bases
GCGGATGGCGGACTCAAGCGCCGGCGCGGCGCGCCCGCAGACACCAAGGCGGCCCTCCCGTCAACGGGGAGGGCCGCTTC
GTTGTCGAGTCAATCGGCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MRRGSQRDFTQGSIPRHIIMFSLPLFAGNLLQMLYNVVDSIWVGQVIGKNALGAVSVSQPLIFALISLVVGLTMATTTLV
GQYRGAGKEELVQRTIGTSLILLAGLGAVVGVLGVLLRYPLLRMIDTPEEIIHDAAAYLAIFMGGILFLFLYNTLGAILR
GLGDANTPLIALAIATVLNIILDGIFILGLGPVPPMGVPGVAIATVVAQGISAIWLARWILKKTDLIRLSRDYWRVDWGL
AGRIFRIGLPAGLQQAVVSFGMVTVTALINSYGPDVVAAFGAAQRLDQAAFLPSMSMGLAVTSVVAQNLGAGKLDRVSAA
VRWCAGLGVAITGLVTLVAVLKPTILIALFNREPDVLAAGSLYLRINGWSYIFFALVFVLGGVMRGAGDTMATLVLTIIG
LWVVRVPAAYLLARSFGMGPAGIWTGILISAIASFLLHLAYYSTGRWKRKVPSVEPAVAERT

Sequences:

>Translated_462_residues
MRRGSQRDFTQGSIPRHIIMFSLPLFAGNLLQMLYNVVDSIWVGQVIGKNALGAVSVSQPLIFALISLVVGLTMATTTLV
GQYRGAGKEELVQRTIGTSLILLAGLGAVVGVLGVLLRYPLLRMIDTPEEIIHDAAAYLAIFMGGILFLFLYNTLGAILR
GLGDANTPLIALAIATVLNIILDGIFILGLGPVPPMGVPGVAIATVVAQGISAIWLARWILKKTDLIRLSRDYWRVDWGL
AGRIFRIGLPAGLQQAVVSFGMVTVTALINSYGPDVVAAFGAAQRLDQAAFLPSMSMGLAVTSVVAQNLGAGKLDRVSAA
VRWCAGLGVAITGLVTLVAVLKPTILIALFNREPDVLAAGSLYLRINGWSYIFFALVFVLGGVMRGAGDTMATLVLTIIG
LWVVRVPAAYLLARSFGMGPAGIWTGILISAIASFLLHLAYYSTGRWKRKVPSVEPAVAERT
>Mature_462_residues
MRRGSQRDFTQGSIPRHIIMFSLPLFAGNLLQMLYNVVDSIWVGQVIGKNALGAVSVSQPLIFALISLVVGLTMATTTLV
GQYRGAGKEELVQRTIGTSLILLAGLGAVVGVLGVLLRYPLLRMIDTPEEIIHDAAAYLAIFMGGILFLFLYNTLGAILR
GLGDANTPLIALAIATVLNIILDGIFILGLGPVPPMGVPGVAIATVVAQGISAIWLARWILKKTDLIRLSRDYWRVDWGL
AGRIFRIGLPAGLQQAVVSFGMVTVTALINSYGPDVVAAFGAAQRLDQAAFLPSMSMGLAVTSVVAQNLGAGKLDRVSAA
VRWCAGLGVAITGLVTLVAVLKPTILIALFNREPDVLAAGSLYLRINGWSYIFFALVFVLGGVMRGAGDTMATLVLTIIG
LWVVRVPAAYLLARSFGMGPAGIWTGILISAIASFLLHLAYYSTGRWKRKVPSVEPAVAERT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI153792564, Length=442, Percent_Identity=25.5656108597285, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI226510954, Length=469, Percent_Identity=21.9616204690832, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI48994890, Length=448, Percent_Identity=22.7678571428571, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320545, Length=431, Percent_Identity=24.1299303944316, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49078; Mature: 49078

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]