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The map label for this gene is rutD [H]

Identifier: 51891945

GI number: 51891945

Start: 903389

End: 904192

Strand: Reverse

Name: rutD [H]

Synonym: STH807

Alternate gene names: 51891945

Gene position: 904192-903389 (Counterclockwise)

Preceding gene: 51891946

Following gene: 51891944

Centisome position: 25.35

GC content: 70.77

Gene sequence:

>804_bases
ATGCCTGAGATTCGCGCCAACGGGATCACGCTCCACTACCAGTGGCGGGGGCAGGAGGACGGCCCGGTGCTGGTCCTCAT
CAACGGCCTGCTCACCGACCTGAGCAGCTGGAACGGCCACCTGCCTCACTTCACCCCGTACTTCCGGGTGCTCACCTACG
ACTGCCGCGGTCAGGGCGCAAGCGAGAAGCCGGACGACGGCCCCTACACGCCTCGGCTTCACGCCGACGACCTGAAGGGG
CTGCTGGACGGACTGGGCGTGGAGAAGGCCGCCCTGCTCGGCGTCTCCAGCGGCGCCTGCGTGGCCCTCAGCTTCGCCGG
CCGGTGGCCCGAACGCGTCTCGGCCCTGGTGCTGGCCAACGGCTACGGCGCGGCCGACACCGCCATGCAGGTGAAGCTGA
ACTCCTGGCTCCGGGCCATGGAGGCCGGCGGCGGGCCGCTGCGGTTCGATGTCTCCGTCGCCTGGATCTGGGGCGCCACC
TTCCTCAACCGGCACTACGAGGCGCTCCGCCCCTGGCGGGAGAAGGGTACCGCCCTGCCAGCCCACGCCGTGCTTCACCT
GATCCGGGGCGCGATGGACCACGACGCGCTGGTCCAGGCCGCGAACATCACCTGCCCGACGCTGCTCATGACCGGCGACG
AGGACGTGCTCACGCCGCTCCGCTACAGCCGAGCCCTGGAGCAGCGGATCCCGGGCAGCCGGGTCGTGGTGCTGCCGGAG
GCCGGCCACTGCATGTTCCTGGAGCAGGTCGACCTGTTCTCCCGGACGGCCCTGGACTTCCTGCGCCAGGCGCTTCTGGC
GTGA

Upstream 100 bases:

>100_bases
CGCGCAAGCAGGCCGCCGGCTGAACCCCCGGCCGGGCAGCCGAGAGCCGGGCCGATCGCGCACGTACGGGCGGAACCGCC
CGAGATGGGGAGGCGAGCAC

Downstream 100 bases:

>100_bases
TCGGAGGCGGAGCGCCGTGACGGAACAGCCCTGGATCGCCTCGTTTGTGGTTCGGCTCACCGGACCGCCGCTCCGGGTCC
TGGTGCGCCACGTGCAGTCC

Product: 3-oxoadipate enol-lactone hydrolase

Products: 3-oxoadipate

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPEIRANGITLHYQWRGQEDGPVLVLINGLLTDLSSWNGHLPHFTPYFRVLTYDCRGQGASEKPDDGPYTPRLHADDLKG
LLDGLGVEKAALLGVSSGACVALSFAGRWPERVSALVLANGYGAADTAMQVKLNSWLRAMEAGGGPLRFDVSVAWIWGAT
FLNRHYEALRPWREKGTALPAHAVLHLIRGAMDHDALVQAANITCPTLLMTGDEDVLTPLRYSRALEQRIPGSRVVVLPE
AGHCMFLEQVDLFSRTALDFLRQALLA

Sequences:

>Translated_267_residues
MPEIRANGITLHYQWRGQEDGPVLVLINGLLTDLSSWNGHLPHFTPYFRVLTYDCRGQGASEKPDDGPYTPRLHADDLKG
LLDGLGVEKAALLGVSSGACVALSFAGRWPERVSALVLANGYGAADTAMQVKLNSWLRAMEAGGGPLRFDVSVAWIWGAT
FLNRHYEALRPWREKGTALPAHAVLHLIRGAMDHDALVQAANITCPTLLMTGDEDVLTPLRYSRALEQRIPGSRVVVLPE
AGHCMFLEQVDLFSRTALDFLRQALLA
>Mature_266_residues
PEIRANGITLHYQWRGQEDGPVLVLINGLLTDLSSWNGHLPHFTPYFRVLTYDCRGQGASEKPDDGPYTPRLHADDLKGL
LDGLGVEKAALLGVSSGACVALSFAGRWPERVSALVLANGYGAADTAMQVKLNSWLRAMEAGGGPLRFDVSVAWIWGATF
LNRHYEALRPWREKGTALPAHAVLHLIRGAMDHDALVQAANITCPTLLMTGDEDVLTPLRYSRALEQRIPGSRVVVLPEA
GHCMFLEQVDLFSRTALDFLRQALLA

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI13376164, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787244, Length=239, Percent_Identity=25.5230125523013, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=118, Percent_Identity=31.3559322033898, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.1.24

Molecular weight: Translated: 29263; Mature: 29132

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIRANGITLHYQWRGQEDGPVLVLINGLLTDLSSWNGHLPHFTPYFRVLTYDCRGQGA
CCCEECCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
SEKPDDGPYTPRLHADDLKGLLDGLGVEKAALLGVSSGACVALSFAGRWPERVSALVLAN
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEECCCCCEEEEEECCCCHHHHEEEEEEC
GYGAADTAMQVKLNSWLRAMEAGGGPLRFDVSVAWIWGATFLNRHYEALRPWREKGTALP
CCCCCCHHEEEHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCHHHCCCCCH
AHAVLHLIRGAMDHDALVQAANITCPTLLMTGDEDVLTPLRYSRALEQRIPGSRVVVLPE
HHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEC
AGHCMFLEQVDLFSRTALDFLRQALLA
CCCEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEIRANGITLHYQWRGQEDGPVLVLINGLLTDLSSWNGHLPHFTPYFRVLTYDCRGQGA
CCEECCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
SEKPDDGPYTPRLHADDLKGLLDGLGVEKAALLGVSSGACVALSFAGRWPERVSALVLAN
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHEEECCCCCEEEEEECCCCHHHHEEEEEEC
GYGAADTAMQVKLNSWLRAMEAGGGPLRFDVSVAWIWGATFLNRHYEALRPWREKGTALP
CCCCCCHHEEEHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCHHHCCCCCH
AHAVLHLIRGAMDHDALVQAANITCPTLLMTGDEDVLTPLRYSRALEQRIPGSRVVVLPE
HHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEC
AGHCMFLEQVDLFSRTALDFLRQALLA
CCCEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxoadipate enol-lactone; H2O

Specific reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA