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The map label for this gene is fabH [H]

Identifier: 51891946

GI number: 51891946

Start: 904270

End: 905322

Strand: Reverse

Name: fabH [H]

Synonym: STH808

Alternate gene names: 51891946

Gene position: 905322-904270 (Counterclockwise)

Preceding gene: 51891947

Following gene: 51891945

Centisome position: 25.39

GC content: 69.42

Gene sequence:

>1053_bases
ATGACCACGACTCAGCCCCACGTCGGTGTGGTCAGCACCGGCATCTACATCCCGGACCGCTACATGACCGCCGAGGAGAT
CGCCGACCGGTCGGGCGTGCCGCTGGACGTGGTGAAGCAGAAGATGGGCATCCTGCGCAAGCCCATCCCCGGCCCCGACG
ACGGCACGGCGGCCATGGGCATCCGGGCCGCGCAGCAGTGCATCGAGCGGGCCGGCATTGACCCGGCCGCCATCGACCTG
GTGATCTACATCGGCGAGGAGTACAAGGAGTACCAGCTGTGGACCGCCGGCATCAAGACGGCGCACGCGGTGGGCGCGCA
CAACGCCTGGGCCTTTGACGCCCAGCTGCGGTGCGGCACCTGGGTGCTGGGCATGAAGCTGGCCCAGGCGCTGATGCTCA
GCGACGACCGGGTGAACACCCTCCTGCTGGCCGGCGGCTACCGGAACGTGGACTACATCAACTACGCCAACCCCCGGGTC
TCCTTCATGTACAACCTCGGAGCCGGCGGCGGGGCGATGCTGCTCCGCAAGAATTACGGCCGCAACCGGGTGGTGGGCTC
GGAGATCATCGTGGACGGCTCGCTCTCCGAGACGGTGGGCGTCCGCGGGGGCGGGACGCTGGCCGGCCTCCACAACCACG
ACGACTCGCTCTACCAGCTGGACGTGTTCGACGTGGAGTACATGAAGACCCGGCTCAACGCCGTGTCGACCCAGCGCTGG
GTGGAGGTGGTCAGCCGGGTCTGCGCGCAGGGCGGCTACCGGACCCAGGACATCGACTACCTGGCGATCCTGCACATGAA
GCGCTCGGCCCACCAGGCCCTGATCGAGCAGCTCGGCATCCCCGTCGACCGGGCGATCTACCTGGAGGAGTACGGCCACA
TCGGCCAGATCGACCAGATCCTCTCCATCCACCTCGCCCTGGAGCGGGGGCTGATCCGGGACGGCGACCTGGTGGTGGGG
GTGAGCGCGGGCGTCGGCTACGCCTGGGGCGCCACGGCCATCGAGTGGGGGCCGGTCGGGGCCACCCGGGCGCGCAAGCA
GGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
TGACTCCCGTGTAACAGCCCGGTGACTCCGGCCCCTTACGTTGGGGGTAAGACCATCGGTGCGAGGCGTTTCAGAAAGCA
CACACGGTGAGGTGCAGCCC

Downstream 100 bases:

>100_bases
ACCCCCGGCCGGGCAGCCGAGAGCCGGGCCGATCGCGCACGTACGGGCGGAACCGCCCGAGATGGGGAGGCGAGCACATG
CCTGAGATTCGCGCCAACGG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTTTQPHVGVVSTGIYIPDRYMTAEEIADRSGVPLDVVKQKMGILRKPIPGPDDGTAAMGIRAAQQCIERAGIDPAAIDL
VIYIGEEYKEYQLWTAGIKTAHAVGAHNAWAFDAQLRCGTWVLGMKLAQALMLSDDRVNTLLLAGGYRNVDYINYANPRV
SFMYNLGAGGGAMLLRKNYGRNRVVGSEIIVDGSLSETVGVRGGGTLAGLHNHDDSLYQLDVFDVEYMKTRLNAVSTQRW
VEVVSRVCAQGGYRTQDIDYLAILHMKRSAHQALIEQLGIPVDRAIYLEEYGHIGQIDQILSIHLALERGLIRDGDLVVG
VSAGVGYAWGATAIEWGPVGATRARKQAAG

Sequences:

>Translated_350_residues
MTTTQPHVGVVSTGIYIPDRYMTAEEIADRSGVPLDVVKQKMGILRKPIPGPDDGTAAMGIRAAQQCIERAGIDPAAIDL
VIYIGEEYKEYQLWTAGIKTAHAVGAHNAWAFDAQLRCGTWVLGMKLAQALMLSDDRVNTLLLAGGYRNVDYINYANPRV
SFMYNLGAGGGAMLLRKNYGRNRVVGSEIIVDGSLSETVGVRGGGTLAGLHNHDDSLYQLDVFDVEYMKTRLNAVSTQRW
VEVVSRVCAQGGYRTQDIDYLAILHMKRSAHQALIEQLGIPVDRAIYLEEYGHIGQIDQILSIHLALERGLIRDGDLVVG
VSAGVGYAWGATAIEWGPVGATRARKQAAG
>Mature_349_residues
TTTQPHVGVVSTGIYIPDRYMTAEEIADRSGVPLDVVKQKMGILRKPIPGPDDGTAAMGIRAAQQCIERAGIDPAAIDLV
IYIGEEYKEYQLWTAGIKTAHAVGAHNAWAFDAQLRCGTWVLGMKLAQALMLSDDRVNTLLLAGGYRNVDYINYANPRVS
FMYNLGAGGGAMLLRKNYGRNRVVGSEIIVDGSLSETVGVRGGGTLAGLHNHDDSLYQLDVFDVEYMKTRLNAVSTQRWV
EVVSRVCAQGGYRTQDIDYLAILHMKRSAHQALIEQLGIPVDRAIYLEEYGHIGQIDQILSIHLALERGLIRDGDLVVGV
SAGVGYAWGATAIEWGPVGATRARKQAAG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=331, Percent_Identity=19.6374622356495, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 38027; Mature: 37896

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTQPHVGVVSTGIYIPDRYMTAEEIADRSGVPLDVVKQKMGILRKPIPGPDDGTAAMG
CCCCCCCCCEEECCEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
IRAAQQCIERAGIDPAAIDLVIYIGEEYKEYQLWTAGIKTAHAVGAHNAWAFDAQLRCGT
HHHHHHHHHHCCCCHHHEEEEEEECCCCHHEEEEHHCCHHHHHCCCCCCEEEECCCCCCH
WVLGMKLAQALMLSDDRVNTLLLAGGYRNVDYINYANPRVSFMYNLGAGGGAMLLRKNYG
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEECCCCCEEEEEECCC
RNRVVGSEIIVDGSLSETVGVRGGGTLAGLHNHDDSLYQLDVFDVEYMKTRLNAVSTQRW
CCCEECCEEEECCCCHHHCCCCCCCEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
VEVVSRVCAQGGYRTQDIDYLAILHMKRSAHQALIEQLGIPVDRAIYLEEYGHIGQIDQI
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCCCCHHHH
LSIHLALERGLIRDGDLVVGVSAGVGYAWGATAIEWGPVGATRARKQAAG
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
TTTQPHVGVVSTGIYIPDRYMTAEEIADRSGVPLDVVKQKMGILRKPIPGPDDGTAAMG
CCCCCCCCEEECCEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
IRAAQQCIERAGIDPAAIDLVIYIGEEYKEYQLWTAGIKTAHAVGAHNAWAFDAQLRCGT
HHHHHHHHHHCCCCHHHEEEEEEECCCCHHEEEEHHCCHHHHHCCCCCCEEEECCCCCCH
WVLGMKLAQALMLSDDRVNTLLLAGGYRNVDYINYANPRVSFMYNLGAGGGAMLLRKNYG
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEECCCCCEEEEEECCC
RNRVVGSEIIVDGSLSETVGVRGGGTLAGLHNHDDSLYQLDVFDVEYMKTRLNAVSTQRW
CCCEECCEEEECCCCHHHCCCCCCCEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
VEVVSRVCAQGGYRTQDIDYLAILHMKRSAHQALIEQLGIPVDRAIYLEEYGHIGQIDQI
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCCCCHHHH
LSIHLALERGLIRDGDLVVGVSAGVGYAWGATAIEWGPVGATRARKQAAG
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA