Click here to switch to the map view.

The map label for this gene is udg [H]

Identifier: 51891923

GI number: 51891923

Start: 882401

End: 883696

Strand: Reverse

Name: udg [H]

Synonym: STH785

Alternate gene names: 51891923

Gene position: 883696-882401 (Counterclockwise)

Preceding gene: 51891927

Following gene: 51891921

Centisome position: 24.78

GC content: 73.77

Gene sequence:

>1296_bases
TTGCCCATCGCCGTAGCCGGCGCAGGCTACGTGGGACTCACCACGGCCGCCTGCCTCTGCGAACTGGGACACGAAGTCGC
GCTTCTGGAGATCGATGGTGAAAGGGTCGCCCGACTGCGGCGGGGCGAATGCCCCTTCTACGAACCGGGGATGGACCGGC
TGCTCCGACGCCACCTGGGCCGGTCGCTGACGGTGACCACGTCACTGGACGAGGCCATTCGCCGTGCCGGGATGATCATC
GTCTGCGTCGGCACCCCGCCGTCCTCCTCCGGCGCTCCCGACCTGCAGGCGCTGTGGAGGCTGCTGGACGACCTGCGGGT
GCGCCGCCCGGCAGAACCCCTGACCGTCGTGCTGAAATCGACCGTTCCGCCCGGCACCAACCGCCGCGCACAGGGCCGGC
TGGGCGCGGGCTTTGCGGTGGTCTCCAATCCCGAGTTCCTGCGGGAGGGCACCGCCATCCACGACTTCTTCCACCCCGAC
CGGATCGTGGTGGGCGCCGAATCCGCCCCGGCGGCCCGGCAGGTCGCCGACCTCTACCGGGGCATCGACGCGCCCCTGGT
GACCACCGGGTGGGAGGAGGCCGAACTCATCAAGTACGCCAGCAACGCGTTCCTGGCGGTGAAGCTCTCCTTTGCCAACG
AGGTCGCCGCCCTGGCCGACGCCCTGGGCGCCGACGGCCTGGCCGTGCTGAAAGGCGTGGGGCTGGACCGGCGCATCGGC
GGCCACTTCCTCCATCCGGGCCCCGGGTACGGGGGCTCCTGCCTGCCCAAGGACCTGGCCGCCCTGCTCTGGACCGCCCG
GCGCAGGCGTGTGCGGCTGGACCTCCTGCCCGCGGCCCGCCGGGCCAACCTCCGGCAGCGGGAGCGGGTGCTGGCCATGC
TGGAACCGGCGGCCGGGCGGCGCATCGCCGTCTGGGGCCTGGCCTTCAAGGCCGGCACCGACGACGTCCGGGAGTCCCCT
GCCCTGGCGATCGTCCCCGCGCTCCTGGCCCAGGGCGCCCGGGTCCTGGCCCACGACCCGCAGGCGCGGGGCAACTTCGC
GGCGGCCCTGGCCGCGGGTCAGGCGCAGGGTCTGCCGGCGGGGCTGGAGCTGGTCGACGATCCCTGGGAGGCGATCCGGG
GCGCCGACGCGCTGCTGGTGCTGACGGAGTGGCCCGAATATGCGGCCGCCCCGCCGGAGGAGATCCGGTCCGCTCTCGCG
GGCGATCTGGTGGTGGACGCCCGCAACCTCTTCGACCCCGCATCCATGGCCGCCGCCGGGCTGCGATACCGGGGCGTGGG
GCGCAGGGGCCGCTGA

Upstream 100 bases:

>100_bases
CCCCCGTGTGCGCAATGCTCAGCATCACCACAGGTTCGCTAAGGCCGGTGGATCTCCTGCGCCATAAGATGGAGCATCAT
CTCCACCGGGGGGAAGCTTC

Downstream 100 bases:

>100_bases
CCACGGGCATGTGTACCGCCGCCGGCGGCGGGCCCCGGTCCGGGGCCCGCCCGGCCGGCAAACAGGCAAACGGGGCTGCC
CCGGCGTCATCGCAGATGAT

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPIAVAGAGYVGLTTAACLCELGHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLGRSLTVTTSLDEAIRRAGMII
VCVGTPPSSSGAPDLQALWRLLDDLRVRRPAEPLTVVLKSTVPPGTNRRAQGRLGAGFAVVSNPEFLREGTAIHDFFHPD
RIVVGAESAPAARQVADLYRGIDAPLVTTGWEEAELIKYASNAFLAVKLSFANEVAALADALGADGLAVLKGVGLDRRIG
GHFLHPGPGYGGSCLPKDLAALLWTARRRRVRLDLLPAARRANLRQRERVLAMLEPAAGRRIAVWGLAFKAGTDDVRESP
ALAIVPALLAQGARVLAHDPQARGNFAAALAAGQAQGLPAGLELVDDPWEAIRGADALLVLTEWPEYAAAPPEEIRSALA
GDLVVDARNLFDPASMAAAGLRYRGVGRRGR

Sequences:

>Translated_431_residues
MPIAVAGAGYVGLTTAACLCELGHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLGRSLTVTTSLDEAIRRAGMII
VCVGTPPSSSGAPDLQALWRLLDDLRVRRPAEPLTVVLKSTVPPGTNRRAQGRLGAGFAVVSNPEFLREGTAIHDFFHPD
RIVVGAESAPAARQVADLYRGIDAPLVTTGWEEAELIKYASNAFLAVKLSFANEVAALADALGADGLAVLKGVGLDRRIG
GHFLHPGPGYGGSCLPKDLAALLWTARRRRVRLDLLPAARRANLRQRERVLAMLEPAAGRRIAVWGLAFKAGTDDVRESP
ALAIVPALLAQGARVLAHDPQARGNFAAALAAGQAQGLPAGLELVDDPWEAIRGADALLVLTEWPEYAAAPPEEIRSALA
GDLVVDARNLFDPASMAAAGLRYRGVGRRGR
>Mature_430_residues
PIAVAGAGYVGLTTAACLCELGHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLGRSLTVTTSLDEAIRRAGMIIV
CVGTPPSSSGAPDLQALWRLLDDLRVRRPAEPLTVVLKSTVPPGTNRRAQGRLGAGFAVVSNPEFLREGTAIHDFFHPDR
IVVGAESAPAARQVADLYRGIDAPLVTTGWEEAELIKYASNAFLAVKLSFANEVAALADALGADGLAVLKGVGLDRRIGG
HFLHPGPGYGGSCLPKDLAALLWTARRRRVRLDLLPAARRANLRQRERVLAMLEPAAGRRIAVWGLAFKAGTDDVRESPA
LAIVPALLAQGARVLAHDPQARGNFAAALAAGQAQGLPAGLELVDDPWEAIRGADALLVLTEWPEYAAAPPEEIRSALAG
DLVVDARNLFDPASMAAAGLRYRGVGRRGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=29.8924731182796, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI296040438, Length=344, Percent_Identity=31.3953488372093, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI296040443, Length=316, Percent_Identity=31.3291139240506, Blast_Score=156, Evalue=5e-38,
Organism=Escherichia coli, GI1788340, Length=344, Percent_Identity=31.3953488372093, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI48994968, Length=444, Percent_Identity=25.2252252252252, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560350, Length=456, Percent_Identity=32.0175438596491, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=29.3361884368308, Blast_Score=217, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 45899; Mature: 45768

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAVAGAGYVGLTTAACLCELGHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLG
CCEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RSLTVTTSLDEAIRRAGMIIVCVGTPPSSSGAPDLQALWRLLDDLRVRRPAEPLTVVLKS
CCEEEECCHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEEC
TVPPGTNRRAQGRLGAGFAVVSNPEFLREGTAIHDFFHPDRIVVGAESAPAARQVADLYR
CCCCCCCCCCCCCCCCCEEEECCHHHHHCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHC
GIDAPLVTTGWEEAELIKYASNAFLAVKLSFANEVAALADALGADGLAVLKGVGLDRRIG
CCCCCEEECCCCHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHCCCCHHHHHCCCCCCCCC
GHFLHPGPGYGGSCLPKDLAALLWTARRRRVRLDLLPAARRANLRQRERVLAMLEPAAGR
CEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCHHHCCHHHHHHHHHHHCCCCCC
RIAVWGLAFKAGTDDVRESPALAIVPALLAQGARVLAHDPQARGNFAAALAAGQAQGLPA
EEEEEEEEEECCCCHHHCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCCCCCC
GLELVDDPWEAIRGADALLVLTEWPEYAAAPPEEIRSALAGDLVVDARNLFDPASMAAAG
CCCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEHHHHCCHHHHHHHC
LRYRGVGRRGR
CCEECCCCCCC
>Mature Secondary Structure 
PIAVAGAGYVGLTTAACLCELGHEVALLEIDGERVARLRRGECPFYEPGMDRLLRRHLG
CEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHCC
RSLTVTTSLDEAIRRAGMIIVCVGTPPSSSGAPDLQALWRLLDDLRVRRPAEPLTVVLKS
CCEEEECCHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEEC
TVPPGTNRRAQGRLGAGFAVVSNPEFLREGTAIHDFFHPDRIVVGAESAPAARQVADLYR
CCCCCCCCCCCCCCCCCEEEECCHHHHHCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHC
GIDAPLVTTGWEEAELIKYASNAFLAVKLSFANEVAALADALGADGLAVLKGVGLDRRIG
CCCCCEEECCCCHHHHHHHHCCEEEEEEEEHHHHHHHHHHHHCCCCHHHHHCCCCCCCCC
GHFLHPGPGYGGSCLPKDLAALLWTARRRRVRLDLLPAARRANLRQRERVLAMLEPAAGR
CEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCHHHCCHHHHHHHHHHHCCCCCC
RIAVWGLAFKAGTDDVRESPALAIVPALLAQGARVLAHDPQARGNFAAALAAGQAQGLPA
EEEEEEEEEECCCCHHHCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCCCCCCCC
GLELVDDPWEAIRGADALLVLTEWPEYAAAPPEEIRSALAGDLVVDARNLFDPASMAAAG
CCCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEHHHHCCHHHHHHHC
LRYRGVGRRGR
CCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]