Click here to switch to the map view.

The map label for this gene is nagB [H]

Identifier: 51598412

GI number: 51598412

Start: 151782

End: 152588

Strand: Direct

Name: nagB [H]

Synonym: BG0150

Alternate gene names: 51598412

Gene position: 151782-152588 (Clockwise)

Preceding gene: 51598411

Following gene: 51598415

Centisome position: 16.79

GC content: 30.73

Gene sequence:

>807_bases
ATGAGATTAATAATCAGACCTACTTATGAAGACATATCGAAGTGGGCAGCCAATCACGTAGCACAAAAAATTAAAGAATT
TTCTCCAACAAGAGAAAAGCCATTTATCCTTGGACTTCCAACAGGAAGTTCTCCAATCGGCATGTACAAGAATTTAATTA
AATTATATAAAGATGAAAAAATTTCATTTCAAAATGTCATAACCTTTAACATGGATGAATACATAGGAATTGAAAAAAAT
CATCCCGAAAGCTACCATTCGTTTATGTGGAAAAATTTTTTTTCTCACATTGATATTAAAAAAGAAAACATAAACATACT
AAATGGAAATGCTTTAAATCTTAAAAAAGAATGTGAAGAGTATGAAAAAAAAATCAAATCTTTTGGGGGAATCATGCTTT
TTGTGGGTGGAATAGGGCCTGATGGACACATCGCTTTTAACGAACCAGGCTCCTCCTTGACATCAAGAACAAGAATTAAA
ACTTTAACTCAAGATACAATCATTGCTAATTCAAGATTTTTTGAAGGCAATGTGAACAAAGTTCCTAAAAGTGCTCTAAC
TGTTGGAGTTGGAACAATTATGGATTCACAAGAAATTTTAATAATAGTAAATGGACACAATAAAGCAAGAGCATTAAAGC
ATGCTATTGAAAAAGGTGTTAATCATATGTGGACAATTAGCGCGCTTCAATTACACAAAAATACAATCATAGTATCTGAC
AAAAAGGCAACTTATGAATTAAAAATCGGAACGGTAGAATACTTTAACGACATAGAAAGAGAAAACTTTAATAATGATTT
AAAATAA

Upstream 100 bases:

>100_bases
TCAATGTCTTAGATAAAGATTTCAATTTAAAATTAACAATGATAGAATCTAAAATAATTTTTAACAATCTCTAACTTTAA
CCCATTTTAAGGAGATCGCA

Downstream 100 bases:

>100_bases
ATTACTTAACATTTTAGAATAAAATACTGGCTCTAAAATTAAAAATTTTATCTTTATAAAGTAAAGCTAATTGTTAGCTT
CATTGTAAATTTTTGAAACT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRLIIRPTYEDISKWAANHVAQKIKEFSPTREKPFILGLPTGSSPIGMYKNLIKLYKDEKISFQNVITFNMDEYIGIEKN
HPESYHSFMWKNFFSHIDIKKENINILNGNALNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGNVNKVPKSALTVGVGTIMDSQEILIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNTIIVSD
KKATYELKIGTVEYFNDIERENFNNDLK

Sequences:

>Translated_268_residues
MRLIIRPTYEDISKWAANHVAQKIKEFSPTREKPFILGLPTGSSPIGMYKNLIKLYKDEKISFQNVITFNMDEYIGIEKN
HPESYHSFMWKNFFSHIDIKKENINILNGNALNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGNVNKVPKSALTVGVGTIMDSQEILIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNTIIVSD
KKATYELKIGTVEYFNDIERENFNNDLK
>Mature_268_residues
MRLIIRPTYEDISKWAANHVAQKIKEFSPTREKPFILGLPTGSSPIGMYKNLIKLYKDEKISFQNVITFNMDEYIGIEKN
HPESYHSFMWKNFFSHIDIKKENINILNGNALNLKKECEEYEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIK
TLTQDTIIANSRFFEGNVNKVPKSALTVGVGTIMDSQEILIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNTIIVSD
KKATYELKIGTVEYFNDIERENFNNDLK

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=61.2403100775194, Blast_Score=347, Evalue=7e-96,
Organism=Homo sapiens, GI19923881, Length=255, Percent_Identity=59.6078431372549, Blast_Score=338, Evalue=3e-93,
Organism=Escherichia coli, GI1786893, Length=262, Percent_Identity=59.5419847328244, Blast_Score=351, Evalue=3e-98,
Organism=Escherichia coli, GI48994958, Length=242, Percent_Identity=32.2314049586777, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789530, Length=231, Percent_Identity=24.2424242424242, Blast_Score=84, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17554876, Length=255, Percent_Identity=58.4313725490196, Blast_Score=316, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24581960, Length=261, Percent_Identity=59.0038314176245, Blast_Score=349, Evalue=9e-97,
Organism=Drosophila melanogaster, GI19920764, Length=261, Percent_Identity=59.0038314176245, Blast_Score=349, Evalue=9e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 30535; Mature: 30535

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIIRPTYEDISKWAANHVAQKIKEFSPTREKPFILGLPTGSSPIGMYKNLIKLYKDEK
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCC
ISFQNVITFNMDEYIGIEKNHPESYHSFMWKNFFSHIDIKKENINILNGNALNLKKECEE
CCEEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHCEEEECCEEEECCCCCCHHHHHHH
YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGNVNK
HHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCEEEECCEEECCCCCC
VPKSALTVGVGTIMDSQEILIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNTIIVSD
CCHHHHHEEHHHEECCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEEC
KKATYELKIGTVEYFNDIERENFNNDLK
CCEEEEEEECHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLIIRPTYEDISKWAANHVAQKIKEFSPTREKPFILGLPTGSSPIGMYKNLIKLYKDEK
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCC
ISFQNVITFNMDEYIGIEKNHPESYHSFMWKNFFSHIDIKKENINILNGNALNLKKECEE
CCEEEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHCEEEECCEEEECCCCCCHHHHHHH
YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGNVNK
HHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHCEEEECCEEECCCCCC
VPKSALTVGVGTIMDSQEILIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNTIIVSD
CCHHHHHEEHHHEECCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEEC
KKATYELKIGTVEYFNDIERENFNNDLK
CCEEEEEEECHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA