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The map label for this gene is intS [H]

Identifier: 51598171

GI number: 51598171

Start: 4636419

End: 4637633

Strand: Reverse

Name: intS [H]

Synonym: YPTB3886

Alternate gene names: 51598171

Gene position: 4637633-4636419 (Counterclockwise)

Preceding gene: 51598172

Following gene: 51598170

Centisome position: 97.74

GC content: 50.37

Gene sequence:

>1215_bases
ATGCCACTAACGGACATTAAGGTGAAAACGGCTAAGCCGATAGATAAGGCTTACAAGCTAACTGACGGGGGCGGCATGTA
TCTGTTGGTTAAACCGAATGGCTCAAAATACTGGCGACTGAAGTACCGTTTTGTCGGCAAGGAAAAGATGCTATCGATCG
GCGTTTATCCGGATGTCTCTTTAGCTGATGCACGCCAAAAGAGAGACGAGGCGCGTAAAGTCTTGGCTGCAGGGGGCGAT
CCTGGTGAGGTGAAGAAGGCGGATAAGCTGGCGCAAAAACTCTCTTCTGAAAACACGTTTGAGGCTATCGCCCGCGAGTG
GCATAAGCAAAAGGCTGATCGTTGGTCTTTACGTTATCGCGATGAAATCATTGATACCTTCGAGAAGGACATATTCCCTT
ACCTTGGTCGACGCCCGATTGCTGAGATTAAGCCAATGGAGCTGCTCGAAACGCTCCGGCGCTTGGAGAAACGCGGTGCG
CTGGAGAAGATGCGTAAAGTACGCCAGCGTTGTGGTGAGGTATTTCGCTATGCCATTGTGACCGGGCGTGCGGAATACAA
CCCGGCCCCCGATCTGGCGACTGCCTTGGCAACGCCAAAGAAAACCCACTTTCCCTTCCTTACCGCAGAAGAACTTCCAT
ATTTCATCAGGGATCTGGCCGGGTACACAGGCAGTGTGATCACTAAAACGGCGACGCAAATCATCATGCAAACGGGGGTT
CGCACTCAGGAACTGCGTTTTGCACGTTGGGAAGATATCGACTTTGAGAAGCGTCTTTGGGAGATCCCTTCTGAAGTGAT
AAAGATGAAGCGGCCACATATCGTTCCGTTGTCGGAGCAGGTTGTGGAGCTGTTTCAGTCGCTGAAGCCGATTACCGGAA
TGTATCCGTTGGTATTTATTGGAAGAAATGACCGGGCAAAGCCGATTTCAAAGGAAAGCGTTAATCAGGTGATTGAGCTG
CTGGGTTATAAGGGAAGGCTGACAGGGCACGGTTTTCGCCACACGATGAGCACGATCTTGCATGAGCAGGGGTTCAACTC
GGCATGGATAGAGACACAGCTGGCTCATGTGGATAAGAATGCGATTCGCGGCACGTACAACCATGCGCATTACCTGGAGG
GAAGACGGGAGATGATGCAGTGGTATGGGGATAATCTTGAATCAATGTTGAATGGTGAAATGATACTACACGGATCATTT
AGCAAGAGTGCATAA

Upstream 100 bases:

>100_bases
CTATTTTTTGGCACCCCCAGGCTATGCGGTAACCCCTTATTCCTCTGACTTGGCTGTGCCACACATACGCCGCGCTGCTT
ATATTTTCAATGGAGATGCT

Downstream 100 bases:

>100_bases
AAGTCACTGCGCACAAAAAATTTGTGAATGTTCCATTTTTTCAATAGTGGTATTTTTTTTGATTAAAATCAATAGATTGA
GGGTTTATGGAAACGTGAAA

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MPLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVSLADARQKRDEARKVLAAGGD
PGEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYRDEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGA
LEKMRKVRQRCGEVFRYAIVTGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGV
RTQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFIGRNDRAKPISKESVNQVIEL
LGYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKNAIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSF
SKSA

Sequences:

>Translated_404_residues
MPLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVSLADARQKRDEARKVLAAGGD
PGEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYRDEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGA
LEKMRKVRQRCGEVFRYAIVTGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGV
RTQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFIGRNDRAKPISKESVNQVIEL
LGYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKNAIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSF
SKSA
>Mature_403_residues
PLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVSLADARQKRDEARKVLAAGGDP
GEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYRDEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGAL
EKMRKVRQRCGEVFRYAIVTGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGVR
TQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFIGRNDRAKPISKESVNQVIELL
GYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKNAIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSFS
KSA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788690, Length=386, Percent_Identity=47.9274611398964, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI145693166, Length=394, Percent_Identity=42.1319796954315, Blast_Score=303, Evalue=9e-84,
Organism=Escherichia coli, GI1788974, Length=397, Percent_Identity=37.5314861460957, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46509; Mature: 46378

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVS
CCCCCCEECCCCCHHHHHEEECCCCEEEEEECCCCCEEEEEEEEECCHHEEEECCCCCCH
LADARQKRDEARKVLAAGGDPGEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGALEKMRKVRQRCGEVFRYAIV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGV
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
RTQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFI
CHHHHHHHHCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEE
GRNDRAKPISKESVNQVIELLGYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSFSKSA
HHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
PLTDIKVKTAKPIDKAYKLTDGGGMYLLVKPNGSKYWRLKYRFVGKEKMLSIGVYPDVS
CCCCCEECCCCCHHHHHEEECCCCEEEEEECCCCCEEEEEEEEECCHHEEEECCCCCCH
LADARQKRDEARKVLAAGGDPGEVKKADKLAQKLSSENTFEAIAREWHKQKADRWSLRYR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DEIIDTFEKDIFPYLGRRPIAEIKPMELLETLRRLEKRGALEKMRKVRQRCGEVFRYAIV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TGRAEYNPAPDLATALATPKKTHFPFLTAEELPYFIRDLAGYTGSVITKTATQIIMQTGV
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
RTQELRFARWEDIDFEKRLWEIPSEVIKMKRPHIVPLSEQVVELFQSLKPITGMYPLVFI
CHHHHHHHHCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEE
GRNDRAKPISKESVNQVIELLGYKGRLTGHGFRHTMSTILHEQGFNSAWIETQLAHVDKN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AIRGTYNHAHYLEGRREMMQWYGDNLESMLNGEMILHGSFSKSA
HHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]