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The map label for this gene is hsdS [H]

Identifier: 51598166

GI number: 51598166

Start: 4631115

End: 4632344

Strand: Reverse

Name: hsdS [H]

Synonym: YPTB3881

Alternate gene names: 51598166

Gene position: 4632344-4631115 (Counterclockwise)

Preceding gene: 51598167

Following gene: 51598165

Centisome position: 97.63

GC content: 39.43

Gene sequence:

>1230_bases
ATGGTGCCTGAGGGGTGGAAGTTATCAACATTTGGTAACCATGTCGATTGTCTCACGGGTTTTGCTTTTAAAAGCAAGAG
TTATTCTAACAATCCTGAGGATATTAGACTACTAAGGGGAGATAATATTGAGCCATCTCGTCTCAGATGGAGAGATGCAA
AATTTTGGCCTGCTCAAGAGTATGAGAAACTTGAAAAGTTTCAATTAAGAAAAGGAGACTTTGTGATCGCAATGGATCGT
ACATGGGTTTCTTCAGGATTAAAAGTCGCTGAAGTCCAACATACTGATATACCATGTCTACTGGTTCAGCGCGTCGCTAG
AATACGAGCACGTTCAACCTTAGAACAGTCACTTCTGAGACAATATTTTTCTGATAATAAGTTTGAACAGTATGTAAAGT
CTGTTCAAACAGCTACGGCTGTGCCTCATATAAGTCCTAATGATATAAAAGATTTCACTTTTCTTCTCCCTCCGATTAAT
GAGCAAAAAAAGATCGCCAGAATCCTTTCTACCTGGGATAAGGCGATCGCTACCACTGAACAACTGCTTGCCAATAGCCA
GCTGCAGAAAAAAGCACTTATGCAGCAATTGCTCACTGGTAAGAAACGTTTTCCTGGGTTTAGTGAAGAGTGGACGGAAG
TTCATCTTTCTGACTTATGCTTCATAAATCCCAGTCGATCAGAAAAACCAGAAAATGGGGTTGTTTCTTTCATCTCTATG
GACGGCGTATCAGAGGATGCGAAATTAATAAAAACTGAAGACAGATATTATTCGGATGTTTCAAAAGGTTTTACATCCTT
CAAAGATGATGATGTGTTAGTCGCGAAGATTACTCCGTGCTTTGAAAATGGGAAAGGTGCTTATGTAATTAATTTAACCA
ATGGTATTGGTTTTGGTAGTACAGAATTTCATGTACTGAGGGCTAAAGAAGGGGTTAACGCAAAATATATTTACTATCTT
ACTGTGATGACGGAGTTCAGGGTGAGAGGTGAAATGAATATGCAGGGTTCTGCTGGTCAAAAACGAGTAACAACAGATTA
TCTTAAATCACTCAAACTCACAGTACCTATCTCATTTACAGAACAGAATAAAATTGCAACTGTTTTAACTGTTTCAGACC
AGGAAATCGCAACACTAAAACAAAAACTCAATCACCTAAAACAAGAAAAAAAAGCCCTGATGCAGCAACTGCTCACCGGT
AAACGCCGGGTTAAGGTGGACGCCGCATGA

Upstream 100 bases:

>100_bases
GAAATTGACCTGATGACGGCCCGTGCCGAGCGTAAGCAACTGCAAGCACAGCTGGCCGATCTGGAAGTGGAGATGACAAA
GTATCTGAGGGAGTTGGGTT

Downstream 100 bases:

>100_bases
CTGATAAACACTTACCTCAACCACCAGCAGGTGAATTCCTGCTGTTTCAAAGCGAGGATGGCCGCGCACGCGTTGAGTGT
CGCTTTCAGTCAGACACGCT

Product: restriction modification enzyme

Products: NA

Alternate protein names: S.StySJI; Type I restriction enzyme StySJI specificity protein; S protein [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MVPEGWKLSTFGNHVDCLTGFAFKSKSYSNNPEDIRLLRGDNIEPSRLRWRDAKFWPAQEYEKLEKFQLRKGDFVIAMDR
TWVSSGLKVAEVQHTDIPCLLVQRVARIRARSTLEQSLLRQYFSDNKFEQYVKSVQTATAVPHISPNDIKDFTFLLPPIN
EQKKIARILSTWDKAIATTEQLLANSQLQKKALMQQLLTGKKRFPGFSEEWTEVHLSDLCFINPSRSEKPENGVVSFISM
DGVSEDAKLIKTEDRYYSDVSKGFTSFKDDDVLVAKITPCFENGKGAYVINLTNGIGFGSTEFHVLRAKEGVNAKYIYYL
TVMTEFRVRGEMNMQGSAGQKRVTTDYLKSLKLTVPISFTEQNKIATVLTVSDQEIATLKQKLNHLKQEKKALMQQLLTG
KRRVKVDAA

Sequences:

>Translated_409_residues
MVPEGWKLSTFGNHVDCLTGFAFKSKSYSNNPEDIRLLRGDNIEPSRLRWRDAKFWPAQEYEKLEKFQLRKGDFVIAMDR
TWVSSGLKVAEVQHTDIPCLLVQRVARIRARSTLEQSLLRQYFSDNKFEQYVKSVQTATAVPHISPNDIKDFTFLLPPIN
EQKKIARILSTWDKAIATTEQLLANSQLQKKALMQQLLTGKKRFPGFSEEWTEVHLSDLCFINPSRSEKPENGVVSFISM
DGVSEDAKLIKTEDRYYSDVSKGFTSFKDDDVLVAKITPCFENGKGAYVINLTNGIGFGSTEFHVLRAKEGVNAKYIYYL
TVMTEFRVRGEMNMQGSAGQKRVTTDYLKSLKLTVPISFTEQNKIATVLTVSDQEIATLKQKLNHLKQEKKALMQQLLTG
KRRVKVDAA
>Mature_409_residues
MVPEGWKLSTFGNHVDCLTGFAFKSKSYSNNPEDIRLLRGDNIEPSRLRWRDAKFWPAQEYEKLEKFQLRKGDFVIAMDR
TWVSSGLKVAEVQHTDIPCLLVQRVARIRARSTLEQSLLRQYFSDNKFEQYVKSVQTATAVPHISPNDIKDFTFLLPPIN
EQKKIARILSTWDKAIATTEQLLANSQLQKKALMQQLLTGKKRFPGFSEEWTEVHLSDLCFINPSRSEKPENGVVSFISM
DGVSEDAKLIKTEDRYYSDVSKGFTSFKDDDVLVAKITPCFENGKGAYVINLTNGIGFGSTEFHVLRAKEGVNAKYIYYL
TVMTEFRVRGEMNMQGSAGQKRVTTDYLKSLKLTVPISFTEQNKIATVLTVSDQEIATLKQKLNHLKQEKKALMQQLLTG
KRRVKVDAA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 46616; Mature: 46616

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPEGWKLSTFGNHVDCLTGFAFKSKSYSNNPEDIRLLRGDNIEPSRLRWRDAKFWPAQE
CCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCHHH
YEKLEKFQLRKGDFVIAMDRTWVSSGLKVAEVQHTDIPCLLVQRVARIRARSTLEQSLLR
HHHHHHHHCCCCCEEEEECCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QYFSDNKFEQYVKSVQTATAVPHISPNDIKDFTFLLPPINEQKKIARILSTWDKAIATTE
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
QLLANSQLQKKALMQQLLTGKKRFPGFSEEWTEVHLSDLCFINPSRSEKPENGVVSFISM
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHEEHHHEEEECCCCCCCCCCCEEEEEEE
DGVSEDAKLIKTEDRYYSDVSKGFTSFKDDDVLVAKITPCFENGKGAYVINLTNGIGFGS
CCCCCCHHHEECCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCEEEEEEECCCCCCCC
TEFHVLRAKEGVNAKYIYYLTVMTEFRVRGEMNMQGSAGQKRVTTDYLKSLKLTVPISFT
CCEEEEEECCCCCEEEEEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHCEEEEEEEEEC
EQNKIATVLTVSDQEIATLKQKLNHLKQEKKALMQQLLTGKRRVKVDAA
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MVPEGWKLSTFGNHVDCLTGFAFKSKSYSNNPEDIRLLRGDNIEPSRLRWRDAKFWPAQE
CCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCHHH
YEKLEKFQLRKGDFVIAMDRTWVSSGLKVAEVQHTDIPCLLVQRVARIRARSTLEQSLLR
HHHHHHHHCCCCCEEEEECCHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QYFSDNKFEQYVKSVQTATAVPHISPNDIKDFTFLLPPINEQKKIARILSTWDKAIATTE
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
QLLANSQLQKKALMQQLLTGKKRFPGFSEEWTEVHLSDLCFINPSRSEKPENGVVSFISM
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHEEHHHEEEECCCCCCCCCCCEEEEEEE
DGVSEDAKLIKTEDRYYSDVSKGFTSFKDDDVLVAKITPCFENGKGAYVINLTNGIGFGS
CCCCCCHHHEECCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCEEEEEEECCCCCCCC
TEFHVLRAKEGVNAKYIYYLTVMTEFRVRGEMNMQGSAGQKRVTTDYLKSLKLTVPISFT
CCEEEEEECCCCCEEEEEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHCEEEEEEEEEC
EQNKIATVLTVSDQEIATLKQKLNHLKQEKKALMQQLLTGKRRVKVDAA
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2838725; 11677609; 3025838 [H]