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The map label for this gene is hsdM

Identifier: 51598167

GI number: 51598167

Start: 4632334

End: 4633857

Strand: Reverse

Name: hsdM

Synonym: YPTB3882

Alternate gene names: 51598167

Gene position: 4633857-4632334 (Counterclockwise)

Preceding gene: 51598168

Following gene: 51598166

Centisome position: 97.66

GC content: 45.6

Gene sequence:

>1524_bases
ATGAGCAATATGATCGATCAGGACCGCATCAACCGCGTGCTATGGGGCGTATGTGACACTTTCCGTGGCACCATCAGCCC
TGATACTTACAAAGATTTCATTCTTACTATGCTGTTTTTGAAGTATATCTCGGATGTCTGGCAGGATCACTATGATGGCT
ACAAAGCCCAATATGGCGATGAACCGGAGCTGATTGAAGAGATGATGAAGAACGAACGCTTTGTTCTACCTAAAGATGCT
AGCTTTTATGCTCTTTATAAGCGTCGAAGTGAGGCGGGTAACGGTGAACGTATCGATGTAGCTCTACACGCAATTGAAGA
AGCTAATGGCACTAAGCTGAAAGATGGTAGTAAGAGCGTGTTCCAGGAAATTTCATTTAATACCAATAAGCTTGGTGATG
AAAAGCAAAAGAATCTGATCTTGAAGCAGTTACTCGAAGATTTTACTCATCCAGAGCTGAATTTGAAACCAAGCCGTGTT
GGTGGCTTGGATGTAATTGGTAACGCTTATGAATATTTGATCGGCAAGTTTGCTGCGAACAGCGGCCAGAAAGCCGGAGA
GTACTATACGCCACCCGAAGTGTCAGATCTGCTCGCGGCGTTGCTTGACCCACAGCCAGGGGAATCTATCTGTGACCCAA
CCTGTGGCTCTGCTTCACTATTGATGAAGTGTGGTAAGTGGGTTGCTGAGAAATACCATAGTAAGAATTACGAGCTTTAT
GGGCAGGAAGCGATTGGTTCAACCTGGTCTCTGGCTAAAATGAACATGTTTCTGCACGGCGAGGATAACCACAAGATCGA
GTGGGGTGATACGATCCGCAACCCCAAGCTACTCGATAAAAATGCCAATCTGATGCTGTTTGATGTGGTCACCGCCAACC
CACCTTTCTCACTGGAAAAGTGGGGAATTGATGACGTTTCTGACGACCAGTTCAGTCGTTTTCGTCGTGGCCTACCGCCT
AAAACCAAGGGCGACTATGCGTTTATCCTGCATATGATCGAAACCATGAAGCCAAAGACTGGACGTATGGGGGTGGTGGT
TCCTCATGGCGTGTTGTTCCGTGGTTCTAGCGAAGGAAAAATTCGGCAGAAGTTGATAGACGAAAATCTTCTCGATGCGG
TGATTGGTTTGCCAGAAAAGCTGTTTTTCGGTACAGGTATACCTGCGGCAATCCTGATATTTAAAAAGAGTAAAGTGGAC
GATAACGTGTTGTTTATCGATGCCAGTCGTGAGTTTAACTCAGGTAAAAATCAAAACCAGCTAAGTACTGAAAATATTGC
CAAAATTGTTAAAACCTATCGTGATGGCGATAACGTCGAAAAATATGCTTATCTTGCCAGTCTGCAGGAGATCCGCGACA
ACGACTATAACCTAAATATTCCCCGCTATGTTGATACATTTGAAGAAGAAACGGAAATTGACCTGATGACGGCCCGTGCC
GAGCGTAAGCAACTGCAAGCACAGCTGGCCGATCTGGAAGTGGAGATGACAAAGTATCTGAGGGAGTTGGGTTATGGTGC
CTGA

Upstream 100 bases:

>100_bases
TGTATGGCAGAAAGAAGATGAACTTATCAATAAGTTACAGAAAAATCGCCATCAGCTTGAGCTTGGTATTTTGCAAAAAT
TACTTAAGGATTAACTTGTT

Downstream 100 bases:

>100_bases
GGGGTGGAAGTTATCAACATTTGGTAACCATGTCGATTGTCTCACGGGTTTTGCTTTTAAAAGCAAGAGTTATTCTAACA
ATCCTGAGGATATTAGACTA

Product: type I site-specific deoxyribonuclease LldI chain hs...

Products: NA

Alternate protein names: M.EcoR124II [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSNMIDQDRINRVLWGVCDTFRGTISPDTYKDFILTMLFLKYISDVWQDHYDGYKAQYGDEPELIEEMMKNERFVLPKDA
SFYALYKRRSEAGNGERIDVALHAIEEANGTKLKDGSKSVFQEISFNTNKLGDEKQKNLILKQLLEDFTHPELNLKPSRV
GGLDVIGNAYEYLIGKFAANSGQKAGEYYTPPEVSDLLAALLDPQPGESICDPTCGSASLLMKCGKWVAEKYHSKNYELY
GQEAIGSTWSLAKMNMFLHGEDNHKIEWGDTIRNPKLLDKNANLMLFDVVTANPPFSLEKWGIDDVSDDQFSRFRRGLPP
KTKGDYAFILHMIETMKPKTGRMGVVVPHGVLFRGSSEGKIRQKLIDENLLDAVIGLPEKLFFGTGIPAAILIFKKSKVD
DNVLFIDASREFNSGKNQNQLSTENIAKIVKTYRDGDNVEKYAYLASLQEIRDNDYNLNIPRYVDTFEEETEIDLMTARA
ERKQLQAQLADLEVEMTKYLRELGYGA

Sequences:

>Translated_507_residues
MSNMIDQDRINRVLWGVCDTFRGTISPDTYKDFILTMLFLKYISDVWQDHYDGYKAQYGDEPELIEEMMKNERFVLPKDA
SFYALYKRRSEAGNGERIDVALHAIEEANGTKLKDGSKSVFQEISFNTNKLGDEKQKNLILKQLLEDFTHPELNLKPSRV
GGLDVIGNAYEYLIGKFAANSGQKAGEYYTPPEVSDLLAALLDPQPGESICDPTCGSASLLMKCGKWVAEKYHSKNYELY
GQEAIGSTWSLAKMNMFLHGEDNHKIEWGDTIRNPKLLDKNANLMLFDVVTANPPFSLEKWGIDDVSDDQFSRFRRGLPP
KTKGDYAFILHMIETMKPKTGRMGVVVPHGVLFRGSSEGKIRQKLIDENLLDAVIGLPEKLFFGTGIPAAILIFKKSKVD
DNVLFIDASREFNSGKNQNQLSTENIAKIVKTYRDGDNVEKYAYLASLQEIRDNDYNLNIPRYVDTFEEETEIDLMTARA
ERKQLQAQLADLEVEMTKYLRELGYGA
>Mature_506_residues
SNMIDQDRINRVLWGVCDTFRGTISPDTYKDFILTMLFLKYISDVWQDHYDGYKAQYGDEPELIEEMMKNERFVLPKDAS
FYALYKRRSEAGNGERIDVALHAIEEANGTKLKDGSKSVFQEISFNTNKLGDEKQKNLILKQLLEDFTHPELNLKPSRVG
GLDVIGNAYEYLIGKFAANSGQKAGEYYTPPEVSDLLAALLDPQPGESICDPTCGSASLLMKCGKWVAEKYHSKNYELYG
QEAIGSTWSLAKMNMFLHGEDNHKIEWGDTIRNPKLLDKNANLMLFDVVTANPPFSLEKWGIDDVSDDQFSRFRRGLPPK
TKGDYAFILHMIETMKPKTGRMGVVVPHGVLFRGSSEGKIRQKLIDENLLDAVIGLPEKLFFGTGIPAAILIFKKSKVDD
NVLFIDASREFNSGKNQNQLSTENIAKIVKTYRDGDNVEKYAYLASLQEIRDNDYNLNIPRYVDTFEEETEIDLMTARAE
RKQLQAQLADLEVEMTKYLRELGYGA

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=482, Percent_Identity=24.0663900414938, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57573; Mature: 57442

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00636 DNAJ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNMIDQDRINRVLWGVCDTFRGTISPDTYKDFILTMLFLKYISDVWQDHYDGYKAQYGD
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EPELIEEMMKNERFVLPKDASFYALYKRRSEAGNGERIDVALHAIEEANGTKLKDGSKSV
CHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEHHHCCCCCCCCCHHHH
FQEISFNTNKLGDEKQKNLILKQLLEDFTHPELNLKPSRVGGLDVIGNAYEYLIGKFAAN
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
SGQKAGEYYTPPEVSDLLAALLDPQPGESICDPTCGSASLLMKCGKWVAEKYHSKNYELY
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
GQEAIGSTWSLAKMNMFLHGEDNHKIEWGDTIRNPKLLDKNANLMLFDVVTANPPFSLEK
EHHHCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCEECCCCCEEEEEEEECCCCCCCCC
WGIDDVSDDQFSRFRRGLPPKTKGDYAFILHMIETMKPKTGRMGVVVPHGVLFRGSSEGK
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCH
IRQKLIDENLLDAVIGLPEKLFFGTGIPAAILIFKKSKVDDNVLFIDASREFNSGKNQNQ
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCC
LSTENIAKIVKTYRDGDNVEKYAYLASLQEIRDNDYNLNIPRYVDTFEEETEIDLMTARA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHH
ERKQLQAQLADLEVEMTKYLRELGYGA
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNMIDQDRINRVLWGVCDTFRGTISPDTYKDFILTMLFLKYISDVWQDHYDGYKAQYGD
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EPELIEEMMKNERFVLPKDASFYALYKRRSEAGNGERIDVALHAIEEANGTKLKDGSKSV
CHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEHHHCCCCCCCCCHHHH
FQEISFNTNKLGDEKQKNLILKQLLEDFTHPELNLKPSRVGGLDVIGNAYEYLIGKFAAN
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
SGQKAGEYYTPPEVSDLLAALLDPQPGESICDPTCGSASLLMKCGKWVAEKYHSKNYELY
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
GQEAIGSTWSLAKMNMFLHGEDNHKIEWGDTIRNPKLLDKNANLMLFDVVTANPPFSLEK
EHHHCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCEECCCCCEEEEEEEECCCCCCCCC
WGIDDVSDDQFSRFRRGLPPKTKGDYAFILHMIETMKPKTGRMGVVVPHGVLFRGSSEGK
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCH
IRQKLIDENLLDAVIGLPEKLFFGTGIPAAILIFKKSKVDDNVLFIDASREFNSGKNQNQ
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCC
LSTENIAKIVKTYRDGDNVEKYAYLASLQEIRDNDYNLNIPRYVDTFEEETEIDLMTARA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHH
ERKQLQAQLADLEVEMTKYLRELGYGA
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]