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The map label for this gene is shlB [H]

Identifier: 51598133

GI number: 51598133

Start: 4589937

End: 4591700

Strand: Reverse

Name: shlB [H]

Synonym: YPTB3843

Alternate gene names: 51598133

Gene position: 4591700-4589937 (Counterclockwise)

Preceding gene: 51598134

Following gene: 51598132

Centisome position: 96.78

GC content: 46.2

Gene sequence:

>1764_bases
ATGATATTTAAAATAAATGTGAGGGGGAGGGATAAAATTGGAGATTTTTGGTGGGGGATATTGTGCCTATTATATCTTCA
AATTATGATTGGGATGCTTCCGTTTAAAGTTTTTGCTGAAATGGCGTTGCCAGAAATGGACCTGCTTGAAATGGATATAG
CCGAGCCGCAGATCCCAAATAGTATTATTCCTCCTCTATCACATGCTCAACTGGCCAGTGAACCGGTTCTGCCAGAGAAT
CTTTATAATGATGAAGTACAATGTGTAGCAATTAATAATGTCGAATTGATTAATCTTGATGCTTTCCCAAATGCAGCTCA
CTTAAAAGAAAAGGCTGAAGAAGCTCACGGGCGTTGCTTGGGGGAACAGGGGCTGTCAGTGCTTGTGGCTAACTTACAGC
AACAATTAGTGGTTGATGGCTATATCACGTCTCGTGTGGTTTTTGTCGGTGACAGTGAGCGTGACGGTACTTTAATGCTG
AAATTAATGCCCGGCAAGATTGAGGATATCAGGCATCATCAAGACAGCGTCGGCAATGCTCATCTCAGCGCCCTTTTCCC
CGGTAAACGTGGTGATTTGGTTAATTTACGCCATCTTGAGCAAGGGTTAGAAAACTTGCAGCGCTTGACTTCAGTGAATG
CCACCCTGGATGTCGAATTAAACCGGGAAGATTTAAGCAGCCAGATTATCGTGAATCGCCAGCAATCACGTCTCTGGCGT
ATTAATGCCTACCTTGATGATGCAGGGCATGATGCCGTTGGCCGCTATCGTACGGGCCTGATATTGTCTTTTGATAATCC
ATTATCCCGTTATAACCCCTTGTCTCTCAGTGATTTACTCTACTTCTCTGTTAACCGTGACCTTGATAGCCAACCCGATA
AAGGGCACAACAGCTACGGGGTTCATTATTCTGTCCCGTATGGCAACTGGCTATTTAGCATGACGGGCAATCAAGGTGAG
CGTTATCAATCGTTCTCTTTTGCCGGTAAAAGACTTGCCGGTAAAAAATTTGGCTATCGTTCCCATTGGTCTGTATTGGA
TACACAAATTCAACATTTACTCACCCGTGGAGTAAATTATAAAACAGTGGGTTATGCCGGGGTGTTAATTCGTCAGTCTG
CCAGTTTTTGGACCCATCGGGAGATAGATATTCAGCGGTTCAATACCACGGACTGGCAGCTAGGGATTGAGCATCTACAT
TACATGCCATGGGCGACGTTCAGAGGGGGGGTTCGTTATCAACAGGGGGCTTCATGGTTTGGTGCCCAACCTATTCCCGG
TAAAATGAGCACTGCACCGGCGAGGTTGGTCGATATCACCAGCTCACTGGATATCCCTTTTAAGATCGGAACACAGTCCT
TCCAGTATCGGCCCGCTTTCAGCCAGCAACATACCTACTCGGATATTAGTTCACTGGATAAATTTACGATTGGTGGCAGG
AGTTCAGTGCGAGGTTTTAATGAGAATAACGCTCTGACGGGGTCGCGGGGGTGGTCTCTAAAAAATGATATTTCATGGAT
CAGCCCGATACCCGGCCAGACATTCGTGGGCCAGCAATTCTATATCGGCATGGATTATGGTGAGGTGAGTGAGCAGGGCC
AACCATTTCTTTTGGGCGAGCGTTTAGCGGGGGCCGTGGTAGGGACTCGTGGAAATTATCATGCGTTTGGTTACGATTTT
AATGTCGGCGTGCCGATAACCAAACCCGCAGAATTTGATGCCGATCCGTTGGTTTTTGGGTTTACGCTAACTTGGCAATA
TTAG

Upstream 100 bases:

>100_bases
TAAGTGAGAGATGATTTTTTATTTAAAGTTAGTTGCTTTCGTGGCTAACTTTTATTGATTTTGTATTAATCGTGTTTTGA
TTGAAATGGAGTTCATTAGC

Downstream 100 bases:

>100_bases
GGTCTATACCTTCTCTGATGTTGAGTGTTTATTGTGCTGCCCTGATTAGGGGCATCACTATGGTGCACCTCTTTGGGAAG
CTATGTGGTTTCTTGGGTGA

Product: TPS family hemolysin activator/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MIFKINVRGRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPEN
LYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVGDSERDGTLML
KLMPGKIEDIRHHQDSVGNAHLSALFPGKRGDLVNLRHLEQGLENLQRLTSVNATLDVELNREDLSSQIIVNRQQSRLWR
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGE
RYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLH
YMPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDF
NVGVPITKPAEFDADPLVFGFTLTWQY

Sequences:

>Translated_587_residues
MIFKINVRGRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPEN
LYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVGDSERDGTLML
KLMPGKIEDIRHHQDSVGNAHLSALFPGKRGDLVNLRHLEQGLENLQRLTSVNATLDVELNREDLSSQIIVNRQQSRLWR
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGE
RYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLH
YMPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDF
NVGVPITKPAEFDADPLVFGFTLTWQY
>Mature_587_residues
MIFKINVRGRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPNSIIPPLSHAQLASEPVLPEN
LYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCLGEQGLSVLVANLQQQLVVDGYITSRVVFVGDSERDGTLML
KLMPGKIEDIRHHQDSVGNAHLSALFPGKRGDLVNLRHLEQGLENLQRLTSVNATLDVELNREDLSSQIIVNRQQSRLWR
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYGVHYSVPYGNWLFSMTGNQGE
RYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNYKTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLH
YMPWATFRGGVRYQQGASWFGAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGERLAGAVVGTRGNYHAFGYDF
NVGVPITKPAEFDADPLVFGFTLTWQY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 66055; Mature: 66055

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKINVRGRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPN
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC
SIIPPLSHAQLASEPVLPENLYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCL
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEE
GEQGLSVLVANLQQQLVVDGYITSRVVFVGDSERDGTLMLKLMPGKIEDIRHHQDSVGNA
CHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCC
HLSALFPGKRGDLVNLRHLEQGLENLQRLTSVNATLDVELNREDLSSQIIVNRQQSRLWR
EEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCEEEECCCCCEEE
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYG
EEEEECCCCCCCCCHHHCEEEEEECCCHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
VHYSVPYGNWLFSMTGNQGERYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNY
EEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLHYMPWATFRGGVRYQQGASWF
EEECEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCEEECCCCCCC
GAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHEECCCC
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCEEEHH
RLAGAVVGTRGNYHAFGYDFNVGVPITKPAEFDADPLVFGFTLTWQY
HHCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MIFKINVRGRDKIGDFWWGILCLLYLQIMIGMLPFKVFAEMALPEMDLLEMDIAEPQIPN
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCC
SIIPPLSHAQLASEPVLPENLYNDEVQCVAINNVELINLDAFPNAAHLKEKAEEAHGRCL
CCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHCCEE
GEQGLSVLVANLQQQLVVDGYITSRVVFVGDSERDGTLMLKLMPGKIEDIRHHQDSVGNA
CHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCC
HLSALFPGKRGDLVNLRHLEQGLENLQRLTSVNATLDVELNREDLSSQIIVNRQQSRLWR
EEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCCEEEECCCCCEEE
INAYLDDAGHDAVGRYRTGLILSFDNPLSRYNPLSLSDLLYFSVNRDLDSQPDKGHNSYG
EEEEECCCCCCCCCHHHCEEEEEECCCHHHCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
VHYSVPYGNWLFSMTGNQGERYQSFSFAGKRLAGKKFGYRSHWSVLDTQIQHLLTRGVNY
EEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KTVGYAGVLIRQSASFWTHREIDIQRFNTTDWQLGIEHLHYMPWATFRGGVRYQQGASWF
EEECEEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCEEECCCCCCC
GAQPIPGKMSTAPARLVDITSSLDIPFKIGTQSFQYRPAFSQQHTYSDISSLDKFTIGGR
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHEECCCC
SSVRGFNENNALTGSRGWSLKNDISWISPIPGQTFVGQQFYIGMDYGEVSEQGQPFLLGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCEEEHH
RLAGAVVGTRGNYHAFGYDFNVGVPITKPAEFDADPLVFGFTLTWQY
HHCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]