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The map label for this gene is hpmA [H]

Identifier: 51598134

GI number: 51598134

Start: 4591809

End: 4593200

Strand: Reverse

Name: hpmA [H]

Synonym: YPTB3844

Alternate gene names: 51598134

Gene position: 4593200-4591809 (Counterclockwise)

Preceding gene: 51598135

Following gene: 51598133

Centisome position: 96.81

GC content: 38.29

Gene sequence:

>1392_bases
ATGAAGTTGACAGATATTAAAACGAAACAGGGATTGTCTATATTGCCTCTCTCTATCATATTGTCGCTCTATGGGAGCTC
AGTTGCTTATGCTGATAATATTATTCCTGATATACAGGCCCCAGCGGGACAGCAAGCGGAAGTCTCTATTATAGAAACAC
CGCCCAGTACATGCCGAGCGCTTACCTCTTACTGTATCGGTATGACAGAGACTGTCGTTAATATTCAAGCGCCTGATGAA
AATGGGTTATCACATAACAAGTATTCTAAATTTGATGTGGTCGCTAATGGCTTATTCGATGTCACGACACTCAATAATCG
CTTAGCTCAAGAGGTTAATGGCAACTCTTTTTTACAAGACAAATCGGCAACCATTATATTAAATGAAGTCAACTCATCAC
ATGCCAGTCTATTAGATGGGAATCTCCGTGTTGACGGGGGAAATGCGCATATTATTATTGCCAATCCAGCAGGTATTAAT
TGTCGAGGGTGCTCTTTTACTAATGCCTCTCATGTGACATTGACGACAGGTACGCCATCTTTTTCTGATAATAAACTAAA
CAGTTTTATTGTTGAGCAGGGAAATATCAATATTGAAAAAAATCCCTCTTACTATATGAGAACAGGTTTACGGTATAAGG
GGGCAGACAAGACTTATCTTGATCTATTCGCAGACACTATTACGGTTAGTGGTGAGATCAATGCGGACGATGGCTATATT
GTCACGGGAAAAAATAAAGTGGGTTTCTCTTTGCCTGGGCAACCATTGCAAGTGTCGCGTTTAGGCAATGAAAATACACC
AGTACCAGGTACGGTTAGTTTGGATGTCAGCGAAATTGGGGGAATGTACACCAATAAAATTCGTATCCATGCAACCGATG
GCACGATTAAAAATAAGGGGGCAATACGCGCGAACGATACACTAAGCCTCAGTTCTGCAGCCAATATAGATAACAGTAAT
GGGAATATATCAGGGAAAATGGTGTTACTGAGTAGCGAGGGTGTTATAAATAACTCTGGTGGCACAATATTAAATAATGG
TGAGTATGATTTATTACCTTCTCAAGGTATTAAAATAACATCTCGTGGCTTAAATAATGAAGGTGGAAAAATAGAGTATA
AAAATGGTAGCGTTGAAATAGCAACAGTTAACACCATCAAAAATGGTAAAGGTACAATTAAAGCAACATCAACGCAAGGG
CGGGTAAGAATAAAACTTCATAGTAATAACCTTAATAATACTGGAGGGAGTATTATTTCTTCAGGGAAAATAGAGGGTAA
AGTTAATAACATACGAAACAATAGAGGGGCTATTATTGGGTTAGGTGGAGTGGATTTGAATGAAACTGTTTTAATTAATG
ATACCGGTAAAATAATTTCTGATTTTAATTAA

Upstream 100 bases:

>100_bases
TTGTTGACTTTTTTTTATGAAAAACCGGTAATGATATCGGTTTTAGACTGTGTTATTCACAACATAACAAACACATTAAT
TATTTAATAAGGGGAATAAT

Downstream 100 bases:

>100_bases
TTTCTTTGTAAGTGAGAGATGATTTTTTATTTAAAGTTAGTTGCTTTCGTGGCTAACTTTTATTGATTTTGTATTAATCG
TGTTTTGATTGAAATGGAGT

Product: hemagglutinin/hemolysin-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKLTDIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN

Sequences:

>Translated_463_residues
MKLTDIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
>Mature_463_residues
MKLTDIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRALTSYCIGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQDKSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGIN
CRGCSFTNASHVTLTTGTPSFSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVRIKLHSNNLNNTGGSIISSGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. HpmA requires hpmB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 49007; Mature: 49007

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRA
CCCCCCCCCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHH
LTSYCIGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHCCCCCEEEC
KSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGINCRGCSFTNASHVTLTTGTPS
CCCEEEEEECCCCCCEEECCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
FSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
CCCCCCEEEEEECCCEEEECCCCEEEECCCEECCCCCCEEEEEEEEEEEEEEEECCCCEE
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCEEEEEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCEEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVRIKLHSNNLNNTGGSIIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
CCEEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC
>Mature Secondary Structure
MKLTDIKTKQGLSILPLSIILSLYGSSVAYADNIIPDIQAPAGQQAEVSIIETPPSTCRA
CCCCCCCCCCCCEEEHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHH
LTSYCIGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVNGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHCCCCCEEEC
KSATIILNEVNSSHASLLDGNLRVDGGNAHIIIANPAGINCRGCSFTNASHVTLTTGTPS
CCCEEEEEECCCCCCEEECCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
FSDNKLNSFIVEQGNINIEKNPSYYMRTGLRYKGADKTYLDLFADTITVSGEINADDGYI
CCCCCCEEEEEECCCEEEECCCCEEEECCCEECCCCCCEEEEEEEEEEEEEEEECCCCEE
VTGKNKVGFSLPGQPLQVSRLGNENTPVPGTVSLDVSEIGGMYTNKIRIHATDGTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCEEEEEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCEEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVRIKLHSNNLNNTGGSIIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKIEGKVNNIRNNRGAIIGLGGVDLNETVLINDTGKIISDFN
CCEEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]