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The map label for this gene is exbB [H]

Identifier: 51597681

GI number: 51597681

Start: 4015577

End: 4016614

Strand: Reverse

Name: exbB [H]

Synonym: YPTB3383

Alternate gene names: 51597681

Gene position: 4016614-4015577 (Counterclockwise)

Preceding gene: 51597684

Following gene: 51597680

Centisome position: 84.66

GC content: 52.02

Gene sequence:

>1038_bases
GTGAAAATAGCTGGCAAAGAGAGTAAAGAGATATCACGAGTGCAAGGCCGGGTGATGAAAGGCGTGATGGTATTATTACT
GGCTACAGGTTTAGCGGGCCATGCACAAGCCGCACCAGGCAACGGCAGTGCGGTTGCGGCTACGGTTACCGCACCCACAG
CGGCAACGTCAACCCCGTTACCTGCACCAGAAATTACCTCGGTTGCTGCAATACCGGAATCAACACCAGAGTCAGTATTA
ACATCAGCATCAGCATTAACCTCAGAATCAATACCGGCCCCTATGGTTCAGCCCGTTACGGCTCCAGTACCACAAAAGCT
GGCGATGGATTTATCTGTCTGGGGTATGTATCAGAATGCGGACGTGGTTGTTAAAGGCGTCATGATTGGTCTGGTGCTGG
CTTCTATCGTCACTTGGACCATTCTGTTCTCTAAAGGGACTGAATTGTTCCGCGCTCGTCGTCGGTTGCGCCAAGAGCAT
GAAGTGATTGGGGCCGTGACCGATCTTGATACCGCTTCGGAGCGAGCAGAAGATTTTGGTCAAGGCAGCGTAAGCAGTTT
GTTACTGCATGAAGCACTGAACGAGCGCCTGTTGTCGATAGAGTCAAATGACAATAATGGCATTAAAGAACGTACTGCTT
TCCGTTTGGAGCGCCGGGTAGCCGCCATTGGCCGCCAAATGGGCAAAGGTAATGGCTTCCTGGCAACAATCGGCGCAATT
TCCCCCTTTGTCGGTTTGTTTGGTACGGTTTGGGGCATCATGAACAGCTTTATCGGCATTGCCCACTCACAGACCACCAA
TCTGGCGGTTGTCGCTCCAGGGATTGCCGAAGCGTTATTGGCAACGGCGTTAGGGCTGGTGGCTGCGATCCCAGCGGTCG
TTATTTATAATATCTTTGCTCGCCAGATCGGAAATTATCGCGCTCAAGTGGGTGATGTCGCGGCACAAGTGTTACTGCTG
TTGAGCCGTGATTTGGATTTGGCCAGTAGCGCCGAAGTAAAGTCCCCTCGCCATCCTCATCAATTACGAGCAGGGTGA

Upstream 100 bases:

>100_bases
CAAATACTAATGATAATTACTATCAATCCGCTGTTTGTTTGATATGATCAAGAGCTGATTTTGTCCTTAAATTGACATGC
ATATTGGGTGGAGGCGCAGC

Downstream 100 bases:

>100_bases
TTTATGGCAATGCGAATGAATGATTCCCTCGACGAGAGTGGAGAATTACACGAAATTAACGTGACGCCGTTTATTGATGT
CATGTTGGTGCTGCTGATTA

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG

Sequences:

>Translated_345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG
>Mature_345_residues
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIPESTPESVL
TSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEH
EVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGDVAAQVLLL
LSRDLDLASSAEVKSPRHPHQLRAG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=236, Percent_Identity=71.1864406779661, Blast_Score=341, Evalue=4e-95,
Organism=Escherichia coli, GI1786958, Length=235, Percent_Identity=31.9148936170213, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 36123; Mature: 36123

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
PAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNA
CCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCC
DVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
QGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
CCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
PAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNA
CCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCC
DVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTASERAEDFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
QGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNGFLATIGAI
CCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
SPFVGLFGTVWGIMNSFIGIAHSQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNIFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]