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The map label for this gene is sufB [H]

Identifier: 51596637

GI number: 51596637

Start: 2729772

End: 2731283

Strand: Reverse

Name: sufB [H]

Synonym: YPTB2313

Alternate gene names: 51596637

Gene position: 2731283-2729772 (Counterclockwise)

Preceding gene: 51596638

Following gene: 51596636

Centisome position: 57.57

GC content: 49.47

Gene sequence:

>1512_bases
ATGACACGAAGCAATGTAGAAATTCCAGATGATGTGCAGGCTTGGGTCAGTGATGGTCGGTATAAAGAGGGCTTTTTTAC
ACACTTGGCCACCGATGAGCTGGCAAAGGGCATCAACGAAGAGGTCGTCCGTGCTATCTCAGCGAAACGTAATGAACCTG
AGTGGATGCTTGAGTTTCGCCTTGGCGCTTACCGAAGTTGGCTCGAGATGGAAGAACCTCACTGGCTGAAGGCCCATTAC
CAAGGTTTGGATTACCAAGATTACAGCTATTATTCTGCGCCATCTTGTGGCAGATGTGATGATAACTGTGATTCGCAGCC
CGGAGCCGTGCAGCAATCCTCTGCTGACGGGAGTGCGCCAAGCAATGCTAACGAATACCTGACCGCGGAGGTAGAGTCTG
CCTTTGCCCAATTGGGGATCCCGGTACGAGAAGGGGCTGAAGTCGCCGTTGATGCTATTTTTGACTCGGTCTCGGTAGCA
ACCACTTATCGGGAAAAGCTGGCGGGCCAGGGGATTATTTTCTGCTCATTCGGCGAGGCTATTCAGGAATACCCTGATTT
AGTGCAGAAATATCTGGGGTCGGTGGTTCCGGCTAAAGATAACTTTTTTGCCGCGCTGAATGCTGCAGTTGCCTCTGATG
GCACCTTTGTGTATGTACCAAAAGGTGTTCGCTGCCCAATGGAGCTCTCCACTTATTTTCGTATCAATGCGGCTAAAACC
GGGCAATTTGAGCGAACTATCCTTATCGCCGACGAAGGCAGTTATGTCAGCTATATCGAAGGGTGCTCGGCACCCGTGCG
CGACAGCTATCAGTTACATGCGGCAGTGGTTGAAGTCATTCTGCACAAAAATGCAGAGGTGAAGTACTCCACCGTGCAAA
ACTGGTTTGCAGGTTCTGACAGTACGGGGGGTATTCTGAACTTCGTGACCAAGCGTGCGTTGTGTGAAGGCGAAGGGTCG
AAGATGTCATGGACGCAATCAGAAACCGGCTCAGCGATTACGTGGAAATACCCCAGTGTGATCCTGCAAGGGGATAACTC
TGTGGGGGAATTCTTCTCGGTGGCGCTAACCAACGGTTATCAGCAAGCAGATACCGGCACTAAAATGATTCATATTGGCA
AAAACACCAAATCAACAATTATTGCCAAAGGTATCTCTGCTGGGCACAGCCAGAATACCTACCGTGGTTTAGTGAAGATC
CTGCCCGGTGCTGACAATGCCCGCAATTTCACACAATGTGACTCTATGTTGATTGGCCCAGATTCTGGCGCCCATACGTT
CCCGTATGTGGAAGTCAGAAATAACACGGCACAGTTGGAACATGAAGCCACAACATCAAAAATTGGTGATGACCAACTGT
TCTATTGCTTGCAGCGCGGTATCAGCGAAGATGATGCTATTTCAATGATCGTCAACGGTTTTTGTAAGGATGTCTTTTCC
GAGCTACCGCTGGAATTTGCTGTCGAAGCACAAAAATTGTTAGCCATTAGTTTGGAGCACAGTGTCGGCTGA

Upstream 100 bases:

>100_bases
TCCGCGAAGGGCTAAACCAGATTTTTAAATTTAATAATCCTAAAGCTCAGCATTCCTGCGGGTGTGGCGAGAGTTTTGGC
GTTTGAGTGATGCAAACTAA

Downstream 100 bases:

>100_bases
TTGTTAGCTGAGTAAGTATTCGCTGCATATACCTAATAGATTTCAACATGCAGGAACGCTGCTTGCAGCGGCCTCGTCGA
GCTGAGGCCCGCGGATGGGA

Product: cysteine desulfurase activator complex subunit SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTRSNVEIPDDVQAWVSDGRYKEGFFTHLATDELAKGINEEVVRAISAKRNEPEWMLEFRLGAYRSWLEMEEPHWLKAHY
QGLDYQDYSYYSAPSCGRCDDNCDSQPGAVQQSSADGSAPSNANEYLTAEVESAFAQLGIPVREGAEVAVDAIFDSVSVA
TTYREKLAGQGIIFCSFGEAIQEYPDLVQKYLGSVVPAKDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKT
GQFERTILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKNAEVKYSTVQNWFAGSDSTGGILNFVTKRALCEGEGS
KMSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGYQQADTGTKMIHIGKNTKSTIIAKGISAGHSQNTYRGLVKI
LPGADNARNFTQCDSMLIGPDSGAHTFPYVEVRNNTAQLEHEATTSKIGDDQLFYCLQRGISEDDAISMIVNGFCKDVFS
ELPLEFAVEAQKLLAISLEHSVG

Sequences:

>Translated_503_residues
MTRSNVEIPDDVQAWVSDGRYKEGFFTHLATDELAKGINEEVVRAISAKRNEPEWMLEFRLGAYRSWLEMEEPHWLKAHY
QGLDYQDYSYYSAPSCGRCDDNCDSQPGAVQQSSADGSAPSNANEYLTAEVESAFAQLGIPVREGAEVAVDAIFDSVSVA
TTYREKLAGQGIIFCSFGEAIQEYPDLVQKYLGSVVPAKDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKT
GQFERTILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKNAEVKYSTVQNWFAGSDSTGGILNFVTKRALCEGEGS
KMSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGYQQADTGTKMIHIGKNTKSTIIAKGISAGHSQNTYRGLVKI
LPGADNARNFTQCDSMLIGPDSGAHTFPYVEVRNNTAQLEHEATTSKIGDDQLFYCLQRGISEDDAISMIVNGFCKDVFS
ELPLEFAVEAQKLLAISLEHSVG
>Mature_502_residues
TRSNVEIPDDVQAWVSDGRYKEGFFTHLATDELAKGINEEVVRAISAKRNEPEWMLEFRLGAYRSWLEMEEPHWLKAHYQ
GLDYQDYSYYSAPSCGRCDDNCDSQPGAVQQSSADGSAPSNANEYLTAEVESAFAQLGIPVREGAEVAVDAIFDSVSVAT
TYREKLAGQGIIFCSFGEAIQEYPDLVQKYLGSVVPAKDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTG
QFERTILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKNAEVKYSTVQNWFAGSDSTGGILNFVTKRALCEGEGSK
MSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGYQQADTGTKMIHIGKNTKSTIIAKGISAGHSQNTYRGLVKIL
PGADNARNFTQCDSMLIGPDSGAHTFPYVEVRNNTAQLEHEATTSKIGDDQLFYCLQRGISEDDAISMIVNGFCKDVFSE
LPLEFAVEAQKLLAISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=504, Percent_Identity=84.3253968253968, Blast_Score=889, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 55082; Mature: 54951

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSNVEIPDDVQAWVSDGRYKEGFFTHLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCHHHHHHHCCCCCCCCHHHHHCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LGAYRSWLEMEEPHWLKAHYQGLDYQDYSYYSAPSCGRCDDNCDSQPGAVQQSSADGSAP
HHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNANEYLTAEVESAFAQLGIPVREGAEVAVDAIFDSVSVATTYREKLAGQGIIFCSFGEA
CCCCCEEEHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
IQEYPDLVQKYLGSVVPAKDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECEEEEEEECCC
GQFERTILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKNAEVKYSTVQNWFAGSD
CCCEEEEEEECCCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
STGGILNFVTKRALCEGEGSKMSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGY
CCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHCCC
QQADTGTKMIHIGKNTKSTIIAKGISAGHSQNTYRGLVKILPGADNARNFTQCDSMLIGP
HHCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHEECCCCCCCCCHHHHCCEEECC
DSGAHTFPYVEVRNNTAQLEHEATTSKIGDDQLFYCLQRGISEDDAISMIVNGFCKDVFS
CCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELPLEFAVEAQKLLAISLEHSVG
HCCHHHHHHHHHHHEEEECCCCC
>Mature Secondary Structure 
TRSNVEIPDDVQAWVSDGRYKEGFFTHLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCHHHHHHHCCCCCCCCHHHHHCHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LGAYRSWLEMEEPHWLKAHYQGLDYQDYSYYSAPSCGRCDDNCDSQPGAVQQSSADGSAP
HHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNANEYLTAEVESAFAQLGIPVREGAEVAVDAIFDSVSVATTYREKLAGQGIIFCSFGEA
CCCCCEEEHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
IQEYPDLVQKYLGSVVPAKDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECEEEEEEECCC
GQFERTILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKNAEVKYSTVQNWFAGSD
CCCEEEEEEECCCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
STGGILNFVTKRALCEGEGSKMSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGY
CCCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHCCC
QQADTGTKMIHIGKNTKSTIIAKGISAGHSQNTYRGLVKILPGADNARNFTQCDSMLIGP
HHCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHEECCCCCCCCCHHHHCCEEECC
DSGAHTFPYVEVRNNTAQLEHEATTSKIGDDQLFYCLQRGISEDDAISMIVNGFCKDVFS
CCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELPLEFAVEAQKLLAISLEHSVG
HCCHHHHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]