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The map label for this gene is pagO [H]

Identifier: 51596525

GI number: 51596525

Start: 2591079

End: 2592002

Strand: Direct

Name: pagO [H]

Synonym: YPTB2199

Alternate gene names: 51596525

Gene position: 2591079-2592002 (Clockwise)

Preceding gene: 51596523

Following gene: 51596532

Centisome position: 54.61

GC content: 36.69

Gene sequence:

>924_bases
ATGCGCAAGGTCATAATATCAATGCTATTTATATTAGTTTCTTTAACCTGGGGCACAACATGGTTGGCAATGAGAATTGC
TGTTGAAACAATTCCACCTATATTTGCCACGGGGATGCGCTTTATATTTGCATCGCCTTTTTTAATCTGCATTGCATTGC
TAACCAAAACACCACTTTTATTTCCAACTGGGCAGCGATTTTTTCAATTTATAATCTGTATATTTTATTTCTCTATCCCT
TTTACGTTAATGATTTATGGTGAGACTTATGTTAGTTCAGGTCTTGCCTCAATTATTTTTTCCAATATGCCAGTGGCAGT
ATTAATCGCATCGGTTATCATTTTAAATGAAAAGACTAATTTAATGCAAATCACAGGGTTAACTATTGCAATGGTTTCTC
TGGCAAGTATCCTCCTTGAGGAGTCAAAAACAGGTGTTGGGAGTCATTGGCAGGGGATTCTAGCTCTTGTTTCCGCTGTG
ATTATACATGCGATTGTATATGCGCAATGCAAGAAAAGGTGCTGCACCGTCTCTGTTATCACATTTAATGCACTTCCTTG
TTTTTGGGCGGGTTTAATTCTTGCATTTGCAGGGTATTTTTTTGAGAAGCCACAACTTGCGAATTTCTCAATTAATTCAA
TGCTATCAACTTTTTACCTTGGCGCTTTTGCTGGAGTATTTGGCATTTTGTGCTATTTTCTGCTCCAACAAAAGGCCAAT
GCTTTTCAGGCCTCTCTTGTATTTTTAATATTCCCTCTGATTGCCGTAAGTTTGGAGAGCTATATCTATGGATATGCAAT
TTCATTTTACTCAATGCTGTTGATAATACCTTTAGCTTTTGGAATACTCATTATTCTTATCTCTAAGAACTATTATGCAG
TAAAGAATCAGGGTAGCGTTACACCGGTAGATATAGAGAAATAA

Upstream 100 bases:

>100_bases
AAGAGAAAATAATTCTCCTAAACCATAAAAAATACATGCATAAGAAAATATTTTTCTCATATTAAAGATATATATTGGTT
TCGTCTGTAGGGGAGGATTT

Downstream 100 bases:

>100_bases
CTATTAGCGTAGGTAAGTCAGCAAAAGTTGAAGCGCAGCCAACAGATAAAACAGGACCAGTTTTGGGCAAAGGTGGGCCA
GCGTTTATCGGGCATAGTGA

Product: DMT superfamily metabolite efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRKVIISMLFILVSLTWGTTWLAMRIAVETIPPIFATGMRFIFASPFLICIALLTKTPLLFPTGQRFFQFIICIFYFSIP
FTLMIYGETYVSSGLASIIFSNMPVAVLIASVIILNEKTNLMQITGLTIAMVSLASILLEESKTGVGSHWQGILALVSAV
IIHAIVYAQCKKRCCTVSVITFNALPCFWAGLILAFAGYFFEKPQLANFSINSMLSTFYLGAFAGVFGILCYFLLQQKAN
AFQASLVFLIFPLIAVSLESYIYGYAISFYSMLLIIPLAFGILIILISKNYYAVKNQGSVTPVDIEK

Sequences:

>Translated_307_residues
MRKVIISMLFILVSLTWGTTWLAMRIAVETIPPIFATGMRFIFASPFLICIALLTKTPLLFPTGQRFFQFIICIFYFSIP
FTLMIYGETYVSSGLASIIFSNMPVAVLIASVIILNEKTNLMQITGLTIAMVSLASILLEESKTGVGSHWQGILALVSAV
IIHAIVYAQCKKRCCTVSVITFNALPCFWAGLILAFAGYFFEKPQLANFSINSMLSTFYLGAFAGVFGILCYFLLQQKAN
AFQASLVFLIFPLIAVSLESYIYGYAISFYSMLLIIPLAFGILIILISKNYYAVKNQGSVTPVDIEK
>Mature_307_residues
MRKVIISMLFILVSLTWGTTWLAMRIAVETIPPIFATGMRFIFASPFLICIALLTKTPLLFPTGQRFFQFIICIFYFSIP
FTLMIYGETYVSSGLASIIFSNMPVAVLIASVIILNEKTNLMQITGLTIAMVSLASILLEESKTGVGSHWQGILALVSAV
IIHAIVYAQCKKRCCTVSVITFNALPCFWAGLILAFAGYFFEKPQLANFSINSMLSTFYLGAFAGVFGILCYFLLQQKAN
AFQASLVFLIFPLIAVSLESYIYGYAISFYSMLLIIPLAFGILIILISKNYYAVKNQGSVTPVDIEK

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 34005; Mature: 34005

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVIISMLFILVSLTWGTTWLAMRIAVETIPPIFATGMRFIFASPFLICIALLTKTPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FPTGQRFFQFIICIFYFSIPFTLMIYGETYVSSGLASIIFSNMPVAVLIASVIILNEKTN
CCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
LMQITGLTIAMVSLASILLEESKTGVGSHWQGILALVSAVIIHAIVYAQCKKRCCTVSVI
EEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEH
TFNALPCFWAGLILAFAGYFFEKPQLANFSINSMLSTFYLGAFAGVFGILCYFLLQQKAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQASLVFLIFPLIAVSLESYIYGYAISFYSMLLIIPLAFGILIILISKNYYAVKNQGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
TPVDIEK
CCCCCCC
>Mature Secondary Structure
MRKVIISMLFILVSLTWGTTWLAMRIAVETIPPIFATGMRFIFASPFLICIALLTKTPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FPTGQRFFQFIICIFYFSIPFTLMIYGETYVSSGLASIIFSNMPVAVLIASVIILNEKTN
CCCHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
LMQITGLTIAMVSLASILLEESKTGVGSHWQGILALVSAVIIHAIVYAQCKKRCCTVSVI
EEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEH
TFNALPCFWAGLILAFAGYFFEKPQLANFSINSMLSTFYLGAFAGVFGILCYFLLQQKAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQASLVFLIFPLIAVSLESYIYGYAISFYSMLLIIPLAFGILIILISKNYYAVKNQGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
TPVDIEK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9712687; 11677609 [H]