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The map label for this gene is mtaD [H]

Identifier: 51596294

GI number: 51596294

Start: 2318657

End: 2320027

Strand: Direct

Name: mtaD [H]

Synonym: YPTB1968

Alternate gene names: 51596294

Gene position: 2318657-2320027 (Clockwise)

Preceding gene: 51596290

Following gene: 51596295

Centisome position: 48.87

GC content: 49.6

Gene sequence:

>1371_bases
ATGCCAGTTTATTTTACCAAGCGTGCTTTTTTACCTGATGGATGGGCTGCAGACGTGCAAATTGCGGTAGATGAGCTGGG
GGATATACAGCGTATCAGCACTGGCAGTAGCAGCAGTGGTTGTCAGGTTTTATCCGGGCCAGTATTACCTGGTATGCCTA
ATCTGCACTCTCATGCTTTTCAGCGCATGATGTCGGGGCTGGCAGAAGTTGCCGGTGATCCACAAGATAGCTTTTGGACT
TGGCGGGATCTCATGTATCGGTTGGTGCAACAACTGACGCCGGAACAGGTTGGTGTTATTGCCCGGCAACTTTATATCGA
AATGCTGAAAGGCGGATATACCCAAGTTGCTGAATTTCACTATTTACATCATAGCCCTGATGGTTCCCCTTACAATGACA
TAGGGGAAATGACGGCCCAATTGAGTCAGGCGGCACAAGACGCTGGGATCGGAATGACTTTATTGCCAGTGCTGTATAGC
TACGCAGGATTTGGTGCTCAACCCGCACAGCAAGGCCAGAGCCGTTTTATTCAGGATACCGAGAGTTATCTCAGACAACA
GCAGGTTATCCGTCGGCAGTTGGCTAATCAGCCTTTACAAAATCAGGGGCTATGTTTCCACTCATTGCGTGCTGTTGAGT
TAAGTCAAATGCAGCAGATTTTACACGTATCGGATAAACAGTTACCGGTACATATTCATATCGCTGAACAACAGAAAGAA
GTTAATGACTGCCTGGCATGGTGTGGCCAGCGCCCGGTTGCTTGGCTATATGGTCACTTACCGGTCGATAGCCGCTGGTG
TCTTGTCCACGCGACACATTTGGATACGTCAGAATTGGTTATGTTAGCCAATAGTCAGGCTGTTGCCGGGTTGTGTCCAA
CGACAGAGGCCAATTTGGGAGATGGTATTTTCCCCGGTGTTGACTATATACATCATCAGGGCCGTTGGGGGATAGGTTCT
GATAGCCATGTTTCGCTGGATGTTGTGGAGGAGCTACGTTGGTTGGAATATGGGCAACGCTTGCGTGATCAACGGCGTAA
CCGTTTGACCTGTGAGCGGCAACCCGCCGTGGCGGATCTATTGTACAGCCAAGCATTAGCCGGAGGGCGTCAGGCTTGCG
GGTGTCAAATTAGCCAGCTAGCCGTAGGCTATCGTGCCGATTGGTTAGTGCTCGATGGCGATGATCCTTATATTGCCGGG
ACAAGATCGGCATCTTTGTTGAATAGATGGTTATTTGCGGGGGGTAAATCGCAAATTCGAGATGTTTATGTGGCAGGCAA
GGCGGTAATCGTGGATAGATATCATCCATTGCAACAGCAAACTGCGCAAGCTTTTCTGGCTGTACTGAAAGCCTGCCAAC
AGGAGGTCTGA

Upstream 100 bases:

>100_bases
GAATTTAGCGTGTGTATATGTATATACAAGTAAGCGATTTAATTAATTGACGCAGCTGCGGAGCGCGTTTGACTCTGAAC
AAAAATATTGGGATATCGCT

Downstream 100 bases:

>100_bases
TGAGTTTTACCGTTTTTGATTTTGCCGGTCTGCCCGTCAGCCGCTGGCGAAATGGTGGCGGCGAAACCCGTGAAATTGCG
TGTTGGCCTGTCGGCGGTGA

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQDSFWT
WRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYS
YAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKE
VNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDGIFPGVDYIHHQGRWGIGS
DSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAVADLLYSQALAGGRQACGCQISQLAVGYRADWLVLDGDDPYIAG
TRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV

Sequences:

>Translated_456_residues
MPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQDSFWT
WRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYS
YAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKE
VNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDGIFPGVDYIHHQGRWGIGS
DSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAVADLLYSQALAGGRQACGCQISQLAVGYRADWLVLDGDDPYIAG
TRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
>Mature_455_residues
PVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQDSFWTW
RDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYSY
AGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKEV
NDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDGIFPGVDYIHHQGRWGIGSD
SHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAVADLLYSQALAGGRQACGCQISQLAVGYRADWLVLDGDDPYIAGT
RSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=431, Percent_Identity=30.1624129930394, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50721; Mature: 50590

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAF
CCCEEECCCCCCCCCCCHHEEEHHHCCCHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHH
QRMMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHH
YLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDT
HHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHH
VNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLG
HHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCHHHEEEEECCCCCCCCCCCCCCCCC
DGIFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAVADL
CCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LYSQALAGGRQACGCQISQLAVGYRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIR
HHHHHHCCCCHHCCCCHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHCCCHHHHH
DVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
EEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAF
CCEEECCCCCCCCCCCHHEEEHHHCCCHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHH
QRMMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHH
YLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDT
HHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHVSDKQLPVHIHIAEQQKE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHH
VNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLG
HHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCHHHEEEEECCCCCCCCCCCCCCCCC
DGIFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQPAVADL
CCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LYSQALAGGRQACGCQISQLAVGYRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIR
HHHHHHCCCCHHCCCCHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHCCCHHHHH
DVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
EEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA