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The map label for this gene is moeB [C]

Identifier: 51596217

GI number: 51596217

Start: 2226643

End: 2228376

Strand: Direct

Name: moeB [C]

Synonym: YPTB1885

Alternate gene names: 51596217

Gene position: 2226643-2228376 (Clockwise)

Preceding gene: 51596216

Following gene: 51596218

Centisome position: 46.93

GC content: 35.52

Gene sequence:

>1734_bases
GTGAGAATACAATTAAATCGAGCACTTCCTTTGACATATGATAAGAGCAATAAAAAAATAGTTGCAGGACAGACTTTCCA
TGACCTAATCGAAATAGACGATTCACCTGATTTTCTTTATGAGTTGCTAACAGATTTAAATGTGGAAACTGAATTAAGCA
TAATCCTGAATAAATATAAAATAGTAGCAGAAGAGTCCTCATACGATATCAATGAGATCATTGAAAATCTTCTTGAGGAA
AAAATAATTATTCATGTCTGGCAACCCGACCGTTATGATAGACATCGTTTATTTTTCGAACTATCAAAAGATAATCATGA
AACCACGATGTCAGCTCTTTCTCTGGCAACCGTTGGCATTATGGGGACTGGTGGTATTGGGTCTAATGTTGCAATACTAC
TAGCAGCGGCTGGGGTTGGCAAACTCAAGATAAGTGATGGTGATCTAATTGAAGAATCTAACCTTACCCGTGCGACTATA
TTTAAAGAAGATCAGATAGGAAGCTTAAAGGTAGCGTCGCTGAAAGAAAATATTTCAGAACGAAATAAAACATGTGGGGT
AGAGGTTCTCCCATTATTACTGAATGAAGAAAATATGGATAAATTTAACGCATTTTTTTCAGAGTGCGATATTATCGTGT
TATCAGCAGATCCTAATAATGTTTTTGAACTTATTAGTATTTTTCATGATAATAATAACATCCCAATTGTCAATGCGGGA
TACTTAGGAAGGCTTGGCCTGATCGGGCCAATGATGGATGCTACTTCCAATCCGGGATTTAAGGAGTTATTTACTCGAGA
TTGTGAAGAAAATCGAACTGGAAAAATACTCATTAATCGCCGATATCAGGCACCATCTTATGGCCCACTAAATTATATGG
TTTCATCAATCTGTTCGCATGAAGTAATACGCTATCTTGCCACAAGGAAAAGTTGTGTTTGGCAAAAAAGATTACTAATA
AATCCTGACACCTATGAAACACTATTTTATGGCTATAAAATAACAGAAGATAATATTGAGATGAAGTGCGATACACTCAA
GCCGGGTGATGAGACAGTTTTTAATAAAATAGCAGGGTATTATAGAGAGCATCGTGACACATCAAGCACGAATAAAACTG
TTCTTGACAAGAGTGTTGCACGAATCCTGACAGAAAATAAATATAATTCAGTTCTTGATGTTGGTTGTGGTATTGGTACG
TATTGTAGGATGTTGGACGGTAAATCTAGTTATATTGTCGGTCTCGATATTAACAGTTCTATGCTTTCAACAGCCAGGGA
GTTAGGCGGTTCAATTGAATATAGCAATGGCGAATTTATGAACTATGATGATAATCATTCCTTTGACCTTGTCATATTTT
CTCTGGTTCTCGACCATGTAGAAAACTTTGTAGATTATATCCTAAAAGCAAAAAGTCTCTTGCATAAAGGTGGGAGTATT
GTATGCATAATTCCTAATCCTGTTAAAGATTCATGTTTAAGTAACGAAGGTAAATATATGGAGGTCACTAACTATTTTCA
TGAAGGAGTTCAGAGAAAAAATCGTTACGATGTCAATGACGAGATCTTATGCGAAGTTTTATCATTTAAGCGAACATTAC
CGACCTATCTAAATGCATTTTTAACTTCAGGTTTTACATTACATTATATTGAAGAACCGAGACATCCTGATAGTAACCAT
CGTGCACATCACATTCCTTATTTTACGATTTTAGAGTTCCGCTATGAACATTGA

Upstream 100 bases:

>100_bases
CTCTTTGTTGTATCATTGGAATTATACCCATCACAATTATGTGGACACTATACAACCGTAACTATTCAAAAAATGAAAAA
ATATTATTGGAGGAATTTAA

Downstream 100 bases:

>100_bases
TAAAATATTTGAAAATCCATCTAATTTAAGGTCATTCGAATTTAATAATGATGTTTGTAAAGTGTTCGATGATATGGTTT
CCCGCAGCGTTCCGGGCTAT

Product: ThiF family protein

Products: NA

Alternate protein names: Methyltransferase; MccB Protein; Molybdopterin Biosynthesis MoeB Protein; Thiamine Biosynthesis Protein ThiF; Molybdopterin/Thiamine Biosynthesis Family Protein; Thiamine/Molybdopterin Biosynthesis ThiF/MoeB-Like Protein; SAM-Dependent Methyltransferase; S-Adenosylmethionine-Dependent Methyltransferase; ThiF Family Protein; Adenylyltransferase ThiF; Methyltransferase Domain Protein; Thiazole Biosynthesis Adenylyltransferase ThiF

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MRIQLNRALPLTYDKSNKKIVAGQTFHDLIEIDDSPDFLYELLTDLNVETELSIILNKYKIVAEESSYDINEIIENLLEE
KIIIHVWQPDRYDRHRLFFELSKDNHETTMSALSLATVGIMGTGGIGSNVAILLAAAGVGKLKISDGDLIEESNLTRATI
FKEDQIGSLKVASLKENISERNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAG
YLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSHEVIRYLATRKSCVWQKRLLI
NPDTYETLFYGYKITEDNIEMKCDTLKPGDETVFNKIAGYYREHRDTSSTNKTVLDKSVARILTENKYNSVLDVGCGIGT
YCRMLDGKSSYIVGLDINSSMLSTARELGGSIEYSNGEFMNYDDNHSFDLVIFSLVLDHVENFVDYILKAKSLLHKGGSI
VCIIPNPVKDSCLSNEGKYMEVTNYFHEGVQRKNRYDVNDEILCEVLSFKRTLPTYLNAFLTSGFTLHYIEEPRHPDSNH
RAHHIPYFTILEFRYEH

Sequences:

>Translated_577_residues
MRIQLNRALPLTYDKSNKKIVAGQTFHDLIEIDDSPDFLYELLTDLNVETELSIILNKYKIVAEESSYDINEIIENLLEE
KIIIHVWQPDRYDRHRLFFELSKDNHETTMSALSLATVGIMGTGGIGSNVAILLAAAGVGKLKISDGDLIEESNLTRATI
FKEDQIGSLKVASLKENISERNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAG
YLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSHEVIRYLATRKSCVWQKRLLI
NPDTYETLFYGYKITEDNIEMKCDTLKPGDETVFNKIAGYYREHRDTSSTNKTVLDKSVARILTENKYNSVLDVGCGIGT
YCRMLDGKSSYIVGLDINSSMLSTARELGGSIEYSNGEFMNYDDNHSFDLVIFSLVLDHVENFVDYILKAKSLLHKGGSI
VCIIPNPVKDSCLSNEGKYMEVTNYFHEGVQRKNRYDVNDEILCEVLSFKRTLPTYLNAFLTSGFTLHYIEEPRHPDSNH
RAHHIPYFTILEFRYEH
>Mature_577_residues
MRIQLNRALPLTYDKSNKKIVAGQTFHDLIEIDDSPDFLYELLTDLNVETELSIILNKYKIVAEESSYDINEIIENLLEE
KIIIHVWQPDRYDRHRLFFELSKDNHETTMSALSLATVGIMGTGGIGSNVAILLAAAGVGKLKISDGDLIEESNLTRATI
FKEDQIGSLKVASLKENISERNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAG
YLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSHEVIRYLATRKSCVWQKRLLI
NPDTYETLFYGYKITEDNIEMKCDTLKPGDETVFNKIAGYYREHRDTSSTNKTVLDKSVARILTENKYNSVLDVGCGIGT
YCRMLDGKSSYIVGLDINSSMLSTARELGGSIEYSNGEFMNYDDNHSFDLVIFSLVLDHVENFVDYILKAKSLLHKGGSI
VCIIPNPVKDSCLSNEGKYMEVTNYFHEGVQRKNRYDVNDEILCEVLSFKRTLPTYLNAFLTSGFTLHYIEEPRHPDSNH
RAHHIPYFTILEFRYEH

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17540406, Length=235, Percent_Identity=27.2340425531915, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 65616; Mature: 65616

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIQLNRALPLTYDKSNKKIVAGQTFHDLIEIDDSPDFLYELLTDLNVETELSIILNKYK
CEEEECCCCCEEEECCCCEEEECCCHHHHEECCCCHHHHHHHHHHCCCCEEHHHEEEEEE
IVAEESSYDINEIIENLLEEKIIIHVWQPDRYDRHRLFFELSKDNHETTMSALSLATVGI
EEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHEEE
MGTGGIGSNVAILLAAAGVGKLKISDGDLIEESNLTRATIFKEDQIGSLKVASLKENISE
EECCCCCCCEEEEEEECCCCEEEECCCCEECCCCCCEEEEEECCCCCCEEHHHHHHHHHH
RNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAG
HCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEECC
YLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSH
CCCCHHCHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
EVIRYLATRKSCVWQKRLLINPDTYETLFYGYKITEDNIEMKCDTLKPGDETVFNKIAGY
HHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHH
YREHRDTSSTNKTVLDKSVARILTENKYNSVLDVGCGIGTYCRMLDGKSSYIVGLDINSS
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCHH
MLSTARELGGSIEYSNGEFMNYDDNHSFDLVIFSLVLDHVENFVDYILKAKSLLHKGGSI
HHHHHHHHCCEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VCIIPNPVKDSCLSNEGKYMEVTNYFHEGVQRKNRYDVNDEILCEVLSFKRTLPTYLNAF
EEEECCCCHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTSGFTLHYIEEPRHPDSNHRAHHIPYFTILEFRYEH
HHCCCEEEEECCCCCCCCCCCCEECCEEEEEEEEECC
>Mature Secondary Structure
MRIQLNRALPLTYDKSNKKIVAGQTFHDLIEIDDSPDFLYELLTDLNVETELSIILNKYK
CEEEECCCCCEEEECCCCEEEECCCHHHHEECCCCHHHHHHHHHHCCCCEEHHHEEEEEE
IVAEESSYDINEIIENLLEEKIIIHVWQPDRYDRHRLFFELSKDNHETTMSALSLATVGI
EEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHEEE
MGTGGIGSNVAILLAAAGVGKLKISDGDLIEESNLTRATIFKEDQIGSLKVASLKENISE
EECCCCCCCEEEEEEECCCCEEEECCCCEECCCCCCEEEEEECCCCCCEEHHHHHHHHHH
RNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAG
HCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEECC
YLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSH
CCCCHHCHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
EVIRYLATRKSCVWQKRLLINPDTYETLFYGYKITEDNIEMKCDTLKPGDETVFNKIAGY
HHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHH
YREHRDTSSTNKTVLDKSVARILTENKYNSVLDVGCGIGTYCRMLDGKSSYIVGLDINSS
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCHH
MLSTARELGGSIEYSNGEFMNYDDNHSFDLVIFSLVLDHVENFVDYILKAKSLLHKGGSI
HHHHHHHHCCEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VCIIPNPVKDSCLSNEGKYMEVTNYFHEGVQRKNRYDVNDEILCEVLSFKRTLPTYLNAF
EEEECCCCHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTSGFTLHYIEEPRHPDSNHRAHHIPYFTILEFRYEH
HHCCCEEEEECCCCCCCCCCCCEECCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA