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The map label for this gene is efeU

Identifier: 51596060

GI number: 51596060

Start: 2082647

End: 2083504

Strand: Direct

Name: efeU

Synonym: YPTB1725

Alternate gene names: 51596060

Gene position: 2082647-2083504 (Clockwise)

Preceding gene: 51596059

Following gene: 51596061

Centisome position: 43.89

GC content: 49.3

Gene sequence:

>858_bases
GTGTTTAGCACGTTCGTCCCATTTCTTATTATGTTTCGTGAAGGGCTGGAGGCGGCACTGATTGTCAGTCTGATTGCCAG
TTACCTCAAGCGTACTCAACGCGGTCAGTGGATGGGCGCAGTCTGGGTTGGTGTGGTGGTGGCAGCGGTGCTTTGTCTCG
CTATCGGTATCTTTATCAATGAAACCACCGGTGAGTTTCCACAGAAACAGCAAGAGCTGTTCGAAGGGATTATCGCTGTA
GTCGCGGTTTGCATATTAACTTATATGGTTTTCTGGATGCGCAAAGTCTCCAAGTCCGTCAAAGTTCACTTGGAAGGGGC
AATTGATAATGCGCTTAACTCTGGGCGCGGCCAAGGTTGGGCATTAGTGGCTATGGTCTTCTTTGCTGTGGCCCGAGAGG
GTCTTGAATCTGTTTTCTTCTTGTTAGCTGCCTTCCAACAGGATGTCGGTATCGGGGCACCTATTGGCGCGATACTCGGG
TTGGTCTGCGCTATTTTGGTCGGAATGGCCATCTATTGGGGCGGCGTTAAATTACATTTAGCCAAATTTTTCAAATGGAC
CAGCCTGTTTATTCTGTTCGTTGCCGCAGGGCTTGCCGCCGGTGCTATCAGAGCCTTTCACGAAGCTGGCTTATGGAACC
ATTTCCAAGATATTGCTTTTGATCTGACCGATGTGCTCTCTACTCACTCATTATTGGGGACGTTCCTTGAAGGGATGTTT
GGCTATCAGGAAGCACCAACGGTGAGCGAAGTGTCTGTCTACTTTATCTATCTTATTCCGGCGTTGATTCTGTTTTTCCT
TCCACCACGTTCCACTGCGGGTTCGGCTATCGCTGCGGCGCGGAAAATTAATCCATAA

Upstream 100 bases:

>100_bases
TTGAATTTCTTTTTATCAGAATGATAATCACAATCGTTTTACTTTTCTTTACGTAAACTGACATGGCCCGTATTTATAAA
TTTAATTACCCACATCAGGG

Downstream 100 bases:

>100_bases
CTAAAATGATCAGTTCAGGGAGTTATTACATGTCTATTTGGTTCTTCCGTCGCACAGCGTTACACGCCGCGTTGTTGTCT
CTGCCTGCTTTCGCTATCAG

Product: oxidase dependent Fe+2 transporter

Products: NA

Alternate protein names: Fe(2+) ion permease efeU; Ferrous iron uptake protein

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFSTFVPFLIMFREGLEAALIVSLIASYLKRTQRGQWMGAVWVGVVVAAVLCLAIGIFINETTGEFPQKQQELFEGIIAV
VAVCILTYMVFWMRKVSKSVKVHLEGAIDNALNSGRGQGWALVAMVFFAVAREGLESVFFLLAAFQQDVGIGAPIGAILG
LVCAILVGMAIYWGGVKLHLAKFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQDIAFDLTDVLSTHSLLGTFLEGMF
GYQEAPTVSEVSVYFIYLIPALILFFLPPRSTAGSAIAAARKINP

Sequences:

>Translated_285_residues
MFSTFVPFLIMFREGLEAALIVSLIASYLKRTQRGQWMGAVWVGVVVAAVLCLAIGIFINETTGEFPQKQQELFEGIIAV
VAVCILTYMVFWMRKVSKSVKVHLEGAIDNALNSGRGQGWALVAMVFFAVAREGLESVFFLLAAFQQDVGIGAPIGAILG
LVCAILVGMAIYWGGVKLHLAKFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQDIAFDLTDVLSTHSLLGTFLEGMF
GYQEAPTVSEVSVYFIYLIPALILFFLPPRSTAGSAIAAARKINP
>Mature_285_residues
MFSTFVPFLIMFREGLEAALIVSLIASYLKRTQRGQWMGAVWVGVVVAAVLCLAIGIFINETTGEFPQKQQELFEGIIAV
VAVCILTYMVFWMRKVSKSVKVHLEGAIDNALNSGRGQGWALVAMVFFAVAREGLESVFFLLAAFQQDVGIGAPIGAILG
LVCAILVGMAIYWGGVKLHLAKFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQDIAFDLTDVLSTHSLLGTFLEGMF
GYQEAPTVSEVSVYFIYLIPALILFFLPPRSTAGSAIAAARKINP

Specific function: Functions only as an uptake system for Fe(2+) ion acquisition

COG id: COG0672

COG function: function code P; High-affinity Fe2+/Pb2+ permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320993, Length=239, Percent_Identity=28.0334728033473, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EFEU_YERPS (Q66BP6)

Other databases:

- EMBL:   BX936398
- RefSeq:   YP_070251.1
- GeneID:   2953793
- GenomeReviews:   BX936398_GR
- KEGG:   yps:YPTB1725
- HOGENOM:   HBG724625
- OMA:   SMVFWMR
- ProtClustDB:   CLSK888988
- BioCyc:   YPSE273123:YPTB1725-MONOMER
- InterPro:   IPR004923

Pfam domain/function: PF03239 FTR1

EC number: NA

Molecular weight: Translated: 31024; Mature: 31024

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1af716c4)-; HASH(0x1ac9ae44)-; HASH(0x1b3327e8)-; HASH(0x1ae13ab8)-; HASH(0x1ae25548)-; HASH(0x1af693c8)-; HASH(0x1afd8984)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCH
>Mature Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA