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The map label for this gene is yrbE [H]

Identifier: 51595424

GI number: 51595424

Start: 1294157

End: 1295290

Strand: Direct

Name: yrbE [H]

Synonym: YPTB1077

Alternate gene names: 51595424

Gene position: 1294157-1295290 (Clockwise)

Preceding gene: 51595423

Following gene: 51595425

Centisome position: 27.28

GC content: 56.17

Gene sequence:

>1134_bases
ATGAAAGAAGTGCGTATTGGATTGATTGGTACCGGGTATATCGGTAAGGCGCACGCCATTGCCTACGCACAGGCACCGAC
GGTGTTTGAATTGCGCGGCAAACTGGTGCGCGAAATGGTGGCCGAAGTCTCACCAGCGCTGGCGGCACAGCGTGCGCAGG
CTTTCGGTTTCAACCGGTTTACCTGCGACTGGCGGGAGCTGGTCGCGGATCCGGCTATTGATGTGGTTGATATTTGCTCA
CCTAATTATCTACATAAAGAGATGGCGCTGGCGGCCATCCACCACGGCAAACATGTCTATGCGGAGAAACCGCTGGCGCT
GAATGCCCGTGACGCCAGCGAGATGGCGGCGGCCGCAACGCGCGCTGGGGTGAAAACGTTGGTAGGGTTCAATTACATCA
AAAACCCCAGTGCGAAGCTGGCTAAAGAGATCATTGAACGTGGTGAAATCGGTGAGGTGATCCACTTTTATGGCACCCAT
AACGAAGACTATATGGCCGATCCCAATACCCCTATTCACTGGCACTGTTTACAAGCGACGGCAGGGCTGGGAACACTTGG
CGATCTGGCGGCCCACATCGTCAGCATGGCGCAATATCTGGTGGGGGAAATAACGCAGGTATGCGGTGATCTGAAAACCG
TCGTGGTGACACGCCCGGCGAGCGTTGGCTCCAGCGCCAGAGTGGCGGTTGAAAACGAAGATCAGGCCCATGCCATGGTG
CGTTTTGTGAATGGCGCTCAGGGAGTGATTGAAGCCTCGCGGGTGGCTTGCGGGCGCAAAATGGGCCTCTCTTACATGAT
TACCGGTACTCAAGGGGCGATCAGTTTTACCCAAGAACGTATGGCGGAACTCAAACTCTACCTGCACAACGACCCGGTCA
ACCGACAAGGCTTCCGTACCCTGCTCGTCGGCCCGACGCACCCAGAGTATGCCGCGTTCTGTATGGCTGCGGGCCACGGT
ATTGGTTTTAACGATCAAAAAACCGTGGAAGTGCGTGACTTGATCGACGGCATCGCGATGGACACGCCGCTGTGGCCCGA
TTTCGCCGAGGGCTGGAAAGTCTCACGCATTCTCGATGCGATTGCTCTGTCTCATCAGGATAGCCGCTGGGTGAATGTGA
CCGACATTGTCTGA

Upstream 100 bases:

>100_bases
AAATTATCACCGGCCTGATCATCGTATTGGCGGTGGCCTTTGATACCTACGCCAAGAACCGTCGCGGCGCGCTGTAATAC
GTTCATGTCAGGAGTGAATG

Downstream 100 bases:

>100_bases
GGATGGGGTATGTCTGAGGATGAGGTATGACAGGGTCTGAGGGGGGGTATGAGTGTGGAAAAGCAATTTAGCGTTAGCGC
GGAAAAGACATGTAATACGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGTLGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPTHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Sequences:

>Translated_377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGTLGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPTHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>Mature_377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGTLGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPTHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=153, Percent_Identity=32.0261437908497, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081947, Length=271, Percent_Identity=25.0922509225092, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=212, Percent_Identity=26.8867924528302, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581117, Length=283, Percent_Identity=25.4416961130742, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41020; Mature: 41020

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRF
CCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAAT
CCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHH
RAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLQAT
HHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHH
AGLGTLGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHHH
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRT
HHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCEE
LLVGPTHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDA
EEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHH
IALSHQDSRWVNVTDIV
HHHCCCCCCEEEEECCC
>Mature Secondary Structure
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRF
CCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAAT
CCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHH
RAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLQAT
HHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHH
AGLGTLGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHHH
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRT
HHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCEE
LLVGPTHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDA
EEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHH
IALSHQDSRWVNVTDIV
HHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]