Click here to switch to the map view.

The map label for this gene is iolC [H]

Identifier: 51595425

GI number: 51595425

Start: 1295339

End: 1297309

Strand: Direct

Name: iolC [H]

Synonym: YPTB1078

Alternate gene names: 51595425

Gene position: 1295339-1297309 (Clockwise)

Preceding gene: 51595424

Following gene: 51595426

Centisome position: 27.3

GC content: 55.71

Gene sequence:

>1971_bases
ATGAGTGTGGAAAAGCAATTTAGCGTTAGCGCGGAAAAGACATGTAATACGGAAAATAAATGTAATACGGAAAAAAAATT
TGATGTCATATGCATGGGCCGCATTGCGGTAGATCTCTACGGTCAGCAGATTGGCGCACGGCTAGAGGATGTTGCCAGCT
TTGCCAAATATCTCGGCGGTTCATCCGGCAACGTGGCTTATGGTTCCGCCCGGCAGGGGCTGCGCTCGTCAATGTTGGCA
CGGGTGGGCGACGAGCATATGGGGCGTTTTCTGCGTGAAGAGCTTCATCAGGTTGGCTGTGATACCAGCCATCTGACCAC
AGATAAAAAGCGGCTCACGGCGCTGGTACTCCTGAGTATTAAAGATCGAGACACCTTTCCGCTGATTTTCTACCGCGATA
ACTGTGCCGATATGGCGATTACGGCGCAGGATTTCAGCGAGCAATACATCGCCTCTGCCCGCTGCCTTGCCATCACGGGC
ACCCATCTTTCTCATCCAAACACTCGTGAAGCGGTACTGACAGCGCTGCGCTATGCACGCCGCAATGGAGTGCGTACCGT
GTTGGATATTGACTACCGCCCGGTACTGTGGGGGCTGACGTCGCTTGGTGACGGCGAAACGCGCTTTATTGAATCCCATC
AGGTCACTGCTGAACTGCTCGCAGTATTCAATTTGTTTGATGTGATTGTGGGGACCGAAGAGGAATTTCATATTGCGGGT
GGCAGCACCAATACGCTGGATGCACTGAGAGGTGTGCGTGAGGTCAGTGACGCTGCGCTGGTGTGCAAGCGGGGGGCGCT
GGGTTGTTCGGTGTACACCGAGGCCATCCCGCAGACCCTTGATGAGGGGTTGACCGTTAGCGGTGTGCGGGTAAAAGTGC
TGAACGTGTTGGGCGCAGGGGACGCATTTATGTCAGGTCTCCTGCGCGGTTATCTCAATGATGAAGGTTGGCCGCAGGCA
TGTCGCTACGCCAATGCTTGTGGCGCACTGGTGGTCTCGCGCCACGGCTGTGCGCCTGCGATGCCGAGTAAAATTGAGCT
GGATAATTATCTGGCGCGGGCAGATGCCGTGGTGCGGCCAGATCTTGATGTGCATCTTAACCATTTACACCGCGTTACGA
CGCGCCGCCGCCAGTGGCCCGAGCTGTGCGTGATGGCCTTTGATCACCGCAGTCAACTCGAAGAAATGGCACTGCAATGC
GGCGCTGATCTGTGCCATATCTCGACGCTCAAGACACTAATTTTACAGGCCAGCCGTGAGGCAGTACACACTGCCGGGCT
GCAGGGGAAAGCGGGGCTGCTGTGCGATGGCACTTTTGGTCAGGACGCCCTTAATGCCATTACGGGAGCAGGCTGGTGGA
TTGGGCGGCCCATTGAACTGCCTGGCTCAAGGCCGCTGGCGATGGAGCACGGCAATATTGGCTCACAACTTATTGGTTGG
CCGCAAGAGCATATCGTCAAGTGTCTGGTGTTCTTCCATCCAGAAGATGCCTACAGCCTACGCCTGGAGCAGGAACAGAA
AATTATTGAGGTGTACCGGGCGTGTTGCCAATCTGGCCACGAACTGCTGCTGGAAGTGATATTACCCGCTGGCATGCCAC
GCAGTGATGAACTCTACCTACGTGCTATTTCACGCTTCTACAATCTCGGGGTCTATCCCGATTGGTGGAAACTGCCGCCA
CTCGCCTCAGAGGGCTGGGCGGCGCTGAACAAACTGATTGAACGGCGCGATCCGCACTGCCGCGGCGTAGTGATCCTTGG
GTTCGATGCCTCACTTGAGGCACTGCGCACAGGCTTTAATGCCGCGGCGGGCTACCCGATAGTCAAAGGTTTTGCCGTAG
GGCGCACGCTGTTTGGTGACGCTTCCCTCGCTTGGCTAAAGCGCGATATTGACGATACGCAGCTTATTGCCCGCATTCGG
GACAACTATCTACAGCTCATTACGCTGTGGCGTGAGCGCGGGCAGAAATAA

Upstream 100 bases:

>100_bases
TGCTCTGTCTCATCAGGATAGCCGCTGGGTGAATGTGACCGACATTGTCTGAGGATGGGGTATGTCTGAGGATGAGGTAT
GACAGGGTCTGAGGGGGGGT

Downstream 100 bases:

>100_bases
TCTTCAGGAGAAACATGACGATGGTGGATCAAAGAACGGCGGTTGAACCAAAAACGGCGGTTGATCAGACAACAGAGGTT
ATTCGAAAAGTAGAAGTTGC

Product: carbohydrate kinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLA
RVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARCLAITG
THLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAG
GSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQA
CRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQC
GADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGW
PQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPP
LASEGWAALNKLIERRDPHCRGVVILGFDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIR
DNYLQLITLWRERGQK

Sequences:

>Translated_656_residues
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLA
RVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARCLAITG
THLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAG
GSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQA
CRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQC
GADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGW
PQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPP
LASEGWAALNKLIERRDPHCRGVVILGFDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIR
DNYLQLITLWRERGQK
>Mature_655_residues
SVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLAR
VGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARCLAITGT
HLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGG
STNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQAC
RYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCG
ADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWP
QEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPL
ASEGWAALNKLIERRDPHCRGVVILGFDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRD
NYLQLITLWRERGQK

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=24.1610738255034, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 72576; Mature: 72445

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGG
CCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSI
CCCCEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHCCCHHHHEEEEEEEEE
KDRDTFPLIFYRDNCADMAITAQDFSEQYIASARCLAITGTHLSHPNTREAVLTALRYAR
CCCCCCEEEEEECCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHH
RNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAG
HCCCEEEEECCCCHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEHHHCCC
DAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHCCEECC
DLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASRE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGW
HHHHCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCEECCCCCCEEEECCCCCCHHCCC
PQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYL
CHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGFDASLEALRTGFN
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCC
AAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
CCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGG
CCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSI
CCCCEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHCCCHHHHEEEEEEEEE
KDRDTFPLIFYRDNCADMAITAQDFSEQYIASARCLAITGTHLSHPNTREAVLTALRYAR
CCCCCCEEEEEECCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHH
RNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAG
HCCCEEEEECCCCHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEHHHCCC
DAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHCCEECC
DLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASRE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGW
HHHHCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCEECCCCCCEEEECCCCCCHHCCC
PQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYL
CHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGFDASLEALRTGFN
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCC
AAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
CCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA