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The map label for this gene is pys2

Identifier: 51594508

GI number: 51594508

Start: 182263

End: 182691

Strand: Direct

Name: pys2

Synonym: YPTB0152

Alternate gene names: 51594508

Gene position: 182263-182691 (Clockwise)

Preceding gene: 51594507

Following gene: 51594509

Centisome position: 3.84

GC content: 41.72

Gene sequence:

>429_bases
GTGTATGTTTATTTAAAAAGTCTTCGTGATGAGCCGGGTGTGGTAACCGGCCGTGGTGAGCGAATTACGGGGATCTGGCT
GGCAGGCGCGGGTAAAGATATGGGGGTACCCATTCCCTCTCAGATTGCCGATAAATTACGTGGCAGGTGGTTTAGTCATT
TTGGTAGATTTAGGGCGGCGTTTTGGCGCGAGGTGGCGAATGATCCTGAGTTGGTTGGTCAGTTTATTATTAGTAATCGC
GAGCGTATGAGTGTAGGTAAGGCCCCTAAAGCTAAAAAAATTGATTCTGGTGGTAAGCGTATACCATTTGAAATCCATCA
TGTTAAATTTATTAAAGATAATGGCGAAGTGTACAATATAGACAATTTGAGAATTTTAACTCCAAAGCTACATATAGAAC
TTCATTCAAAAAATAAAGGTAAGCAATGA

Upstream 100 bases:

>100_bases
TTAGTAACGTAAATATTAATTCAATAATTTATTTTCTCATCTTGGGAGATGTTTCCACGATGACATTATCTGGTTCCCGG
CAGATTCCGGGCTGGAGCCA

Downstream 100 bases:

>100_bases
AACTAAAAAATAGTATTTCTGAATATACGGAAGAAGAATTTATTGATTTTTTAAAGGAGATATTTAAAGAAAATATTGCG
GACACAGATGCTCGACTGAA

Product: pyocin S2 (partial)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MYVYLKSLRDEPGVVTGRGERITGIWLAGAGKDMGVPIPSQIADKLRGRWFSHFGRFRAAFWREVANDPELVGQFIISNR
ERMSVGKAPKAKKIDSGGKRIPFEIHHVKFIKDNGEVYNIDNLRILTPKLHIELHSKNKGKQ

Sequences:

>Translated_142_residues
MYVYLKSLRDEPGVVTGRGERITGIWLAGAGKDMGVPIPSQIADKLRGRWFSHFGRFRAAFWREVANDPELVGQFIISNR
ERMSVGKAPKAKKIDSGGKRIPFEIHHVKFIKDNGEVYNIDNLRILTPKLHIELHSKNKGKQ
>Mature_142_residues
MYVYLKSLRDEPGVVTGRGERITGIWLAGAGKDMGVPIPSQIADKLRGRWFSHFGRFRAAFWREVANDPELVGQFIISNR
ERMSVGKAPKAKKIDSGGKRIPFEIHHVKFIKDNGEVYNIDNLRILTPKLHIELHSKNKGKQ

Specific function: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the colicin/pyosin nuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003058
- InterPro:   IPR003615
- InterPro:   IPR016128 [H]

Pfam domain/function: PF03515 Cloacin [H]

EC number: 3.1.21.1

Molecular weight: Translated: 16151; Mature: 16151

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVYLKSLRDEPGVVTGRGERITGIWLAGAGKDMGVPIPSQIADKLRGRWFSHFGRFRAA
CEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FWREVANDPELVGQFIISNRERMSVGKAPKAKKIDSGGKRIPFEIHHVKFIKDNGEVYNI
HHHHHCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEC
DNLRILTPKLHIELHSKNKGKQ
CCEEEECCEEEEEEECCCCCCC
>Mature Secondary Structure
MYVYLKSLRDEPGVVTGRGERITGIWLAGAGKDMGVPIPSQIADKLRGRWFSHFGRFRAA
CEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FWREVANDPELVGQFIISNRERMSVGKAPKAKKIDSGGKRIPFEIHHVKFIKDNGEVYNI
HHHHHCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEC
DNLRILTPKLHIELHSKNKGKQ
CCEEEECCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1603061; 10368275 [H]