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The map label for this gene is pys2

Identifier: 51594506

GI number: 51594506

Start: 181435

End: 181854

Strand: Direct

Name: pys2

Synonym: YPTB0150

Alternate gene names: 51594506

Gene position: 181435-181854 (Clockwise)

Preceding gene: 51594505

Following gene: 51594507

Centisome position: 3.82

GC content: 40.95

Gene sequence:

>420_bases
GTGTATGTTTATTTAAAAAGTCCTCGTGATGAGCCGGGTGTAGTAACCGGTCGTGGTGAGCGAATTACGGGGATCTGGCT
GGCAGGTGCGGGTAAAGATATGGGGGCACCCATTCCCGCTCAGATTGCCGATAAATTACGTGGCAGGCGGTTTAGTCATT
TTGGTAGATTTAGGGCGGCGTTTTGGAAGGTAGTTGGGGAAGACCCAAATTTAGTTAAATATTTTAAATCGGGTAATCTA
GGAAATATTAAAAATGGTAAAGTACCATCTCCTAAAGAACGTGAGCAAGTAGGCAGACGAGTAAAGTATGAACTTCATCA
TCTGAAGCCTATTAGTAAAAATGGTGCTGTTTACCACATTGAAAATATTAGAGTATTAACTCCGAAAAGGCATATAGATA
TTCATAAAGGAGCAGAATAA

Upstream 100 bases:

>100_bases
ATTAATGGCATAAATATTAATTCAATATTTATTTTCCCATCTCGGGAGATGTTTCCACGATGATATTATCTGGTTCCCGG
CAGATTCCGGGCTGGAGCCA

Downstream 100 bases:

>100_bases
TATGGAAGATAAAAGTATTTGTGATTACACTGAATCTGAATTTTTAGAATTAGTAAAGGAGCTTTTTAATGTGGAAAAAA
CGACTGAAGAAGAAGATATT

Product: pyocin S2 (partial)

Products: NA

Alternate protein names: Killer protein [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MYVYLKSPRDEPGVVTGRGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAAFWKVVGEDPNLVKYFKSGNL
GNIKNGKVPSPKEREQVGRRVKYELHHLKPISKNGAVYHIENIRVLTPKRHIDIHKGAE

Sequences:

>Translated_139_residues
MYVYLKSPRDEPGVVTGRGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAAFWKVVGEDPNLVKYFKSGNL
GNIKNGKVPSPKEREQVGRRVKYELHHLKPISKNGAVYHIENIRVLTPKRHIDIHKGAE
>Mature_139_residues
MYVYLKSPRDEPGVVTGRGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAAFWKVVGEDPNLVKYFKSGNL
GNIKNGKVPSPKEREQVGRRVKYELHHLKPISKNGAVYHIENIRVLTPKRHIDIHKGAE

Specific function: Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the colicin/pyosin nuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR003060
- InterPro:   IPR010715
- InterPro:   IPR016128 [H]

Pfam domain/function: PF06958 Pyocin_S [H]

EC number: 3.1.21.1

Molecular weight: Translated: 15694; Mature: 15694

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVYLKSPRDEPGVVTGRGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAA
CEEEECCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
FWKVVGEDPNLVKYFKSGNLGNIKNGKVPSPKEREQVGRRVKYELHHLKPISKNGAVYHI
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ENIRVLTPKRHIDIHKGAE
CCEEEECCCCEEEECCCCC
>Mature Secondary Structure
MYVYLKSPRDEPGVVTGRGERITGIWLAGAGKDMGAPIPAQIADKLRGRRFSHFGRFRAA
CEEEECCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHH
FWKVVGEDPNLVKYFKSGNLGNIKNGKVPSPKEREQVGRRVKYELHHLKPISKNGAVYHI
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ENIRVLTPKRHIDIHKGAE
CCEEEECCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8491711; 10984043 [H]