Click here to switch to the map view.

The map label for this gene is celR [H]

Identifier: 50843733

GI number: 50843733

Start: 2492189

End: 2493196

Strand: Direct

Name: celR [H]

Synonym: PPA2296

Alternate gene names: 50843733

Gene position: 2492189-2493196 (Clockwise)

Preceding gene: 50843729

Following gene: 50843735

Centisome position: 97.34

GC content: 61.81

Gene sequence:

>1008_bases
ATGAGTGCGGAAACAGGCCGACCCACTATGCACGAGGTAGCTCGGGTCGCCGGTGTCTCCCATGCCACAGTGTCACGGGT
CCTCAACGGCCACACCAACGTTGCCCCCGCAACCGCACGAGCTGTCGCCGACGCGATCATTACCACCGGTTATGTACCCA
ATCGAGCAGCACGGTCGCTACGAGTCCAGTCCACCGACACTGTGGTCCTCGTAGCCCGCGAAAAAGCCGACGTTTTCTAC
AGTGAGCCAACTCTGTCGCCGATGGCATCGGGAGCGAATCTTCGCCTCTCTGAGCACGGGTACCAGATGCTGCTAGCCCT
CGTCGATTCTTCCCGATCCGCTGAGCGGGTCGGGTCATTGATTGCCGGGGGATCTTTCGACGCGGCAATTTTGGTAGCGA
TGAGCAACGACGACCCGCTGATCGCGCGTCTTATGGCCACAAATACTCCCCTCGTAACCTCATCCACGCCGTTTCCGGGC
TTTGACATCCCTTCAGCTGACACCGACAACGTCGGAGGTTCCCGGGCTATCACCGCGCGACTCGTAGCCACTGGTCGGTC
AAAATTAGTCGCTATCGGAGGGCCATCGTGGGCCCCGGTCACCCAGCTGCGTCTCGACGGGTTCCACCAAGGTGCGAAAA
ATGCCGCCTTAGGGCACACCACAGTCAATGAATGGACCCTCACCGCCGGCAAGCGGGCAATGAGGGAACTCCTTGAGCTT
CACCCGGACCTCGACGGTGTTGTCGCGGCCTCAGATCTGCTGGCGGCGGGAGCAACCCGAGCCCTCAACGAGGTCGGTCG
GCGGGTCCCACAGGACGTCGGCGTCGTCGGGTTCGACGATGCACCAATCGCGGCTCTCAACGATCCTCCGCTGTCGACGG
TGCGCAGCGATGCCAGGGCAACGGGAATTGCCTTAGCCGACATGGCTATCGCGCAGATTCGCGGCCAGGAGCTCCCCCAA
CCCCACCTCCTACTACCCAACGAAGTAGTTTGGCGAGAGTCGGCCTGA

Upstream 100 bases:

>100_bases
TGTACACGTGTACATTACGACTCGTGGCCCACCTCCGACAAGTGGGGTCGCACAACCGAGCGTCACCGATGGTGGACCGG
AATAATGAGGAGGATTGTCG

Downstream 100 bases:

>100_bases
CCGGTCCGTCAGACCACCGACGGGCGTTGCAGGTCGGTGTAGTTAACGGCCTTGGCATCAAGAAGTTCGACAAAAGCGTC
GAACCCGTTGGCCTCCAGCC

Product: transcription regulator CelR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSAETGRPTMHEVARVAGVSHATVSRVLNGHTNVAPATARAVADAIITTGYVPNRAARSLRVQSTDTVVLVAREKADVFY
SEPTLSPMASGANLRLSEHGYQMLLALVDSSRSAERVGSLIAGGSFDAAILVAMSNDDPLIARLMATNTPLVTSSTPFPG
FDIPSADTDNVGGSRAITARLVATGRSKLVAIGGPSWAPVTQLRLDGFHQGAKNAALGHTTVNEWTLTAGKRAMRELLEL
HPDLDGVVAASDLLAAGATRALNEVGRRVPQDVGVVGFDDAPIAALNDPPLSTVRSDARATGIALADMAIAQIRGQELPQ
PHLLLPNEVVWRESA

Sequences:

>Translated_335_residues
MSAETGRPTMHEVARVAGVSHATVSRVLNGHTNVAPATARAVADAIITTGYVPNRAARSLRVQSTDTVVLVAREKADVFY
SEPTLSPMASGANLRLSEHGYQMLLALVDSSRSAERVGSLIAGGSFDAAILVAMSNDDPLIARLMATNTPLVTSSTPFPG
FDIPSADTDNVGGSRAITARLVATGRSKLVAIGGPSWAPVTQLRLDGFHQGAKNAALGHTTVNEWTLTAGKRAMRELLEL
HPDLDGVVAASDLLAAGATRALNEVGRRVPQDVGVVGFDDAPIAALNDPPLSTVRSDARATGIALADMAIAQIRGQELPQ
PHLLLPNEVVWRESA
>Mature_334_residues
SAETGRPTMHEVARVAGVSHATVSRVLNGHTNVAPATARAVADAIITTGYVPNRAARSLRVQSTDTVVLVAREKADVFYS
EPTLSPMASGANLRLSEHGYQMLLALVDSSRSAERVGSLIAGGSFDAAILVAMSNDDPLIARLMATNTPLVTSSTPFPGF
DIPSADTDNVGGSRAITARLVATGRSKLVAIGGPSWAPVTQLRLDGFHQGAKNAALGHTTVNEWTLTAGKRAMRELLELH
PDLDGVVAASDLLAAGATRALNEVGRRVPQDVGVVGFDDAPIAALNDPPLSTVRSDARATGIALADMAIAQIRGQELPQP
HLLLPNEVVWRESA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=338, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790369, Length=333, Percent_Identity=26.7267267267267, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=26.625386996904, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=28.7009063444109, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=32.3333333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786540, Length=343, Percent_Identity=27.1137026239067, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787906, Length=343, Percent_Identity=27.9883381924198, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=29.4915254237288, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787948, Length=322, Percent_Identity=27.639751552795, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994940, Length=317, Percent_Identity=27.1293375394322, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=23.98753894081, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789456, Length=323, Percent_Identity=23.5294117647059, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790689, Length=330, Percent_Identity=24.8484848484848, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35021; Mature: 34890

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAETGRPTMHEVARVAGVSHATVSRVLNGHTNVAPATARAVADAIITTGYVPNRAARSL
CCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHEE
RVQSTDTVVLVAREKADVFYSEPTLSPMASGANLRLSEHGYQMLLALVDSSRSAERVGSL
EEECCCEEEEEEECCCCEEECCCCCCHHCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHH
IAGGSFDAAILVAMSNDDPLIARLMATNTPLVTSSTPFPGFDIPSADTDNVGGSRAITAR
HCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHEEEE
LVATGRSKLVAIGGPSWAPVTQLRLDGFHQGAKNAALGHTTVNEWTLTAGKRAMRELLEL
EEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
HPDLDGVVAASDLLAAGATRALNEVGRRVPQDVGVVGFDDAPIAALNDPPLSTVRSDARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECCCCCEEECCCCCHHHHHHHHHH
TGIALADMAIAQIRGQELPQPHLLLPNEVVWRESA
HHHHHHHHHHHHHCCCCCCCCCEECCCCEECCCCC
>Mature Secondary Structure 
SAETGRPTMHEVARVAGVSHATVSRVLNGHTNVAPATARAVADAIITTGYVPNRAARSL
CCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHEE
RVQSTDTVVLVAREKADVFYSEPTLSPMASGANLRLSEHGYQMLLALVDSSRSAERVGSL
EEECCCEEEEEEECCCCEEECCCCCCHHCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHH
IAGGSFDAAILVAMSNDDPLIARLMATNTPLVTSSTPFPGFDIPSADTDNVGGSRAITAR
HCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHEEEE
LVATGRSKLVAIGGPSWAPVTQLRLDGFHQGAKNAALGHTTVNEWTLTAGKRAMRELLEL
EEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
HPDLDGVVAASDLLAAGATRALNEVGRRVPQDVGVVGFDDAPIAALNDPPLSTVRSDARA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECCCCCEEECCCCCHHHHHHHHHH
TGIALADMAIAQIRGQELPQPHLLLPNEVVWRESA
HHHHHHHHHHHHHCCCCCCCCCEECCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]