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The map label for this gene is ykuT [H]

Identifier: 50843735

GI number: 50843735

Start: 2494023

End: 2494880

Strand: Direct

Name: ykuT [H]

Synonym: PPA2298

Alternate gene names: 50843735

Gene position: 2494023-2494880 (Clockwise)

Preceding gene: 50843733

Following gene: 50843737

Centisome position: 97.41

GC content: 58.39

Gene sequence:

>858_bases
ATGCCTCCGCTGAAATCCGACGTGTGGACATGGGACACACTCATCCACATCGCCATCATCATCGCTGTAGCGATCATCGC
CCGTTGGCTGCTCCGCAAGGGCGTTGATTGGACGATTCATCTCATGGTGTCGCGCTCCGAGAAACGCGAAGCGACGATGC
CAGGCCGCACGCGTCGTATCCTCGCAGAGGCGACCGGCGCGAGCATCGATCGACAAAATCAGCGCACCGCAACCGTTGGC
GGGCTTCTTTCGAATGTCGGTGTGACGATCATCATCATCGTCGCCCTGCTTTCGGGATTCAGCACCATCGGCTTCAAGAT
CACCCCCATCCTCACCTCCGCCGGAATTGTTGGCGTGGCGCTAGCCTTTGGCGCACAGACGCTCGTCAAAGACGTCCTGG
CGGGACTTTTCATCATCTTCGAGGACCAGTACGGCGTCGGTGACGCGGTGAAAATCAATGAAGTGGAGGGGCTCGTTGAA
GATGTCGGCCTACGTGTGACGCGGATCCGGGATTGGAATGGCGCAGCCTGGTATCTACGCAACGGTGAGATCACCAAGGT
GGGCAATGTCACTCAGGGCTGGACGACCTCGTTTACTGACATCAACGTGCACGCCTTGGAAGATCCCAACCAGGTGATCC
GCGTCATCCGTAAGGTTCTCGACAACCTCGAAGTCGAATTTGAAGGAACCCTACTCGACAAGCCGCTGGTGCTGGGCGTC
GGCGACATCACCGGCGACACGATGACCTTCCAGGTCATGACGAAATGCATCGCCAACCAGCACAATAATGTTCTGCGCGC
CCTGCGCCGCGAGTGTAAGGACGCCTTCGACGCGGCTCGGATCCGCAGGGTTTTCTGA

Upstream 100 bases:

>100_bases
TCTAGCGTGTCCGGGGCGGGGGTTTTCTTGCCCGACGTGGGAAGGTGGAAGTGTTACTGAGAGCACATCCACCGCCTGAA
CCCGACCGCGAAGGGAGACC

Downstream 100 bases:

>100_bases
TCGACAGTCCGGTCTTCCTTTTCACCACGATCCCAAGTTTCCTCGGCCCCGGCCATCGCCAGATACCACGTGGTACACCT
TTCGTGGGCAGAGAACTCGC

Product: putative mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MPPLKSDVWTWDTLIHIAIIIAVAIIARWLLRKGVDWTIHLMVSRSEKREATMPGRTRRILAEATGASIDRQNQRTATVG
GLLSNVGVTIIIIVALLSGFSTIGFKITPILTSAGIVGVALAFGAQTLVKDVLAGLFIIFEDQYGVGDAVKINEVEGLVE
DVGLRVTRIRDWNGAAWYLRNGEITKVGNVTQGWTTSFTDINVHALEDPNQVIRVIRKVLDNLEVEFEGTLLDKPLVLGV
GDITGDTMTFQVMTKCIANQHNNVLRALRRECKDAFDAARIRRVF

Sequences:

>Translated_285_residues
MPPLKSDVWTWDTLIHIAIIIAVAIIARWLLRKGVDWTIHLMVSRSEKREATMPGRTRRILAEATGASIDRQNQRTATVG
GLLSNVGVTIIIIVALLSGFSTIGFKITPILTSAGIVGVALAFGAQTLVKDVLAGLFIIFEDQYGVGDAVKINEVEGLVE
DVGLRVTRIRDWNGAAWYLRNGEITKVGNVTQGWTTSFTDINVHALEDPNQVIRVIRKVLDNLEVEFEGTLLDKPLVLGV
GDITGDTMTFQVMTKCIANQHNNVLRALRRECKDAFDAARIRRVF
>Mature_284_residues
PPLKSDVWTWDTLIHIAIIIAVAIIARWLLRKGVDWTIHLMVSRSEKREATMPGRTRRILAEATGASIDRQNQRTATVGG
LLSNVGVTIIIIVALLSGFSTIGFKITPILTSAGIVGVALAFGAQTLVKDVLAGLFIIFEDQYGVGDAVKINEVEGLVED
VGLRVTRIRDWNGAAWYLRNGEITKVGNVTQGWTTSFTDINVHALEDPNQVIRVIRKVLDNLEVEFEGTLLDKPLVLGVG
DITGDTMTFQVMTKCIANQHNNVLRALRRECKDAFDAARIRRVF

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=291, Percent_Identity=28.8659793814433, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31429; Mature: 31298

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLKSDVWTWDTLIHIAIIIAVAIIARWLLRKGVDWTIHLMVSRSEKREATMPGRTRRI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHH
LAEATGASIDRQNQRTATVGGLLSNVGVTIIIIVALLSGFSTIGFKITPILTSAGIVGVA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHHHCHHHHHH
LAFGAQTLVKDVLAGLFIIFEDQYGVGDAVKINEVEGLVEDVGLRVTRIRDWNGAAWYLR
HHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEEEECCCEEEEEE
NGEITKVGNVTQGWTTSFTDINVHALEDPNQVIRVIRKVLDNLEVEFEGTLLDKPLVLGV
CCCEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECEEECCCEEEEE
GDITGDTMTFQVMTKCIANQHNNVLRALRRECKDAFDAARIRRVF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPLKSDVWTWDTLIHIAIIIAVAIIARWLLRKGVDWTIHLMVSRSEKREATMPGRTRRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHH
LAEATGASIDRQNQRTATVGGLLSNVGVTIIIIVALLSGFSTIGFKITPILTSAGIVGVA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHHHCHHHHHH
LAFGAQTLVKDVLAGLFIIFEDQYGVGDAVKINEVEGLVEDVGLRVTRIRDWNGAAWYLR
HHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHCCEEEEEEECCCEEEEEE
NGEITKVGNVTQGWTTSFTDINVHALEDPNQVIRVIRKVLDNLEVEFEGTLLDKPLVLGV
CCCEEECCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECEEECCCEEEEE
GDITGDTMTFQVMTKCIANQHNNVLRALRRECKDAFDAARIRRVF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]