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The map label for this gene is sglT [H]

Identifier: 50843630

GI number: 50843630

Start: 2375688

End: 2377637

Strand: Direct

Name: sglT [H]

Synonym: PPA2193

Alternate gene names: 50843630

Gene position: 2375688-2377637 (Clockwise)

Preceding gene: 50843627

Following gene: 50843631

Centisome position: 92.79

GC content: 58.31

Gene sequence:

>1950_bases
ATGGCGTGGGGTGTCTGCGACATAAATGGCTCCTTTGCCGGTCAAAATCCCGTGACAACGAGGCTGAGCGTACGACGATG
CCAGTGGCGCTGCGTCGACTTCGCTCACTCAAAATGTTTACGTACTCAAAATTACCGGGTGCAGATGCGCTCATGCCGCA
CCGGGGTCTATGGTTCCCCACGGGGCGACGCCAACGAGGCCGTTCCTCCCCCGCACCAACCGAAAGGACCACTCCGCACC
ATGCCGTTGGAGACACTCATCAACGCAGGGTTCGTTGATTACCTGATACTGCTCATTTACTTCGTGTTCGTCCTGGGAAT
CGGACTGGCCGCCAGACATCAGGTGTCCGACTCCCTCGACTTCTTCTTGTCCGGACGCAGCCTGCCCGGATGGGTGACAG
GGCTGGCATTCGTGTCGGCGAACCTCGGCGCCGTCGAGATCATGGGAATGTCGGCTAATGGAGCCCAGATCGGCATCCCG
ACGGTCCATTACTTTTGGATCGGCGCTATACCCGCGATGGTGTTCCTTGGCATCGTCATGATGCCCTTCTACTACGGCTC
CGGTGTGCGCTCCGTGCCAGAGTTCATGCTCAAACGGTTCGGCCCAGCAGCGCACCTCGTTAACGCGATCTCCTTCGCGC
TAGCCCAGCTTCTTATCGCCGGTATCAACCTGTACCTGCTTGGAACCATCGTCCATGCCCTGCTGGGATGGCCGCTATGG
GTTGCCCTCATCGTTGCCGCGATGATCGTGCTCGCTTACATCAGCCTTGGTGGCTTGTCGGCGGCTATTTATAACGAGGT
GCTGCAATTCTTCGTCATCGTCGCTTCCCTCCTACCCCTTGTCATCATCGGTTTGCATCGGGTAGGTGGCTGGAGTGGCC
TCAAGGCCAAGATCACTGCTGCCGCCGAGGCTCATCCTGACGTCGTGACGCCGGCTGCCCAGCAGCTTCATTCCTGGCCT
GGCCAAGCATTGTCCGGATTCGGCAGTCCAGTGATGTCTGTCATTGGCATCACGCTCGGACTCGGATTCGTGCTGTCTTT
TGGCTACTGGACGACGAATTTCGTCGAGGTGCAGCGGGCAATGGCATCCGATTCTCTGTCGTCTGCACGCAAGACGCCGA
CTATCGGGGCCTTCCCGAAGATGCTCGTGCCCTTCCTCACCGTTTTGCCAGGCATGCTCGCTGCGGTCCTCGTCCCTGAA
ATTGCCCGCATGAAGGCTGGTGAGAAGGTTGCTGGTGGCGCGTCAGGTAGTTTCGTCCAGTACAACGATTCTGTGCTGTT
TCTCATCCGCAACCTGTTGCCGACCGGTCTGACGGGCGTGGCGATCACAGGTCTGCTAGCTGCGTTCATGGCTGGTATGG
CGGCGAATATTTCGGCGTTCAACACCGTTTTCAGCGTGGACATCTGGCAGCACTACGTCATTAAGGACAAGCCCGACGGC
TACTACGTCAAGGTGGGACGCATTGCCACAGTCATCGCGACCGTCGTCGCCATTGGAACGGCGTTTATGGCGTCCGGGTT
CTCCAACATCATGGACTACTTGCAGACGTTGTTCGGATTCTTCAACGCTCCGTTGTTTGCAACGTTTATCCTCGGCATGT
TCTGGAAGCGCTCAACCCCGCATGCAGGCTGGTCGGGCCTGGTCGTCGGCACGCTAAGTGCGGTGACGGTGTGGGTTATG
AGCCTAGCGGGAGTTTTTACCTTGCCAGGCCAGGGGACGGCATTCCTTGCCGCTACGGTCGGATTCGTCGCAGATATCAT
CGTCAGCATTGTGGTGTCCTTGTTTACCGAGCCTAAGCCTGCAGCAGAGCTGGTCAGGTTGGTGTACTCGGAGACCCCGA
AGGAGCACCTCGTCGACCCACTGGAGAAGGATCTCCCGTGGTATCGCCGTACGGTCCCGCTCGGCATGACCGTGCTCGCC
ATCACCGTCGTTCTCAACATCATTTTCTGA

Upstream 100 bases:

>100_bases
GCTACCACCAATGTGCCCGCCAAAGAGGTGCCGGGCGCGAGTGGCACCCTCCTCTACCGACCATGCTGTGCCGATCGTCG
GGGTCTGGTGGTCTGCCGCA

Downstream 100 bases:

>100_bases
GGAGCTTGCCATGTCCAACGGAACTGCTACGGCTCGTCGCAATCGCAGTAAGGTCGCTCGCGCGATGGACATTCGGACCG
TCATAGGTGTGCTGCTCGGC

Product: sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MAWGVCDINGSFAGQNPVTTRLSVRRCQWRCVDFAHSKCLRTQNYRVQMRSCRTGVYGSPRGDANEAVPPPHQPKGPLRT
MPLETLINAGFVDYLILLIYFVFVLGIGLAARHQVSDSLDFFLSGRSLPGWVTGLAFVSANLGAVEIMGMSANGAQIGIP
TVHYFWIGAIPAMVFLGIVMMPFYYGSGVRSVPEFMLKRFGPAAHLVNAISFALAQLLIAGINLYLLGTIVHALLGWPLW
VALIVAAMIVLAYISLGGLSAAIYNEVLQFFVIVASLLPLVIIGLHRVGGWSGLKAKITAAAEAHPDVVTPAAQQLHSWP
GQALSGFGSPVMSVIGITLGLGFVLSFGYWTTNFVEVQRAMASDSLSSARKTPTIGAFPKMLVPFLTVLPGMLAAVLVPE
IARMKAGEKVAGGASGSFVQYNDSVLFLIRNLLPTGLTGVAITGLLAAFMAGMAANISAFNTVFSVDIWQHYVIKDKPDG
YYVKVGRIATVIATVVAIGTAFMASGFSNIMDYLQTLFGFFNAPLFATFILGMFWKRSTPHAGWSGLVVGTLSAVTVWVM
SLAGVFTLPGQGTAFLAATVGFVADIIVSIVVSLFTEPKPAAELVRLVYSETPKEHLVDPLEKDLPWYRRTVPLGMTVLA
ITVVLNIIF

Sequences:

>Translated_649_residues
MAWGVCDINGSFAGQNPVTTRLSVRRCQWRCVDFAHSKCLRTQNYRVQMRSCRTGVYGSPRGDANEAVPPPHQPKGPLRT
MPLETLINAGFVDYLILLIYFVFVLGIGLAARHQVSDSLDFFLSGRSLPGWVTGLAFVSANLGAVEIMGMSANGAQIGIP
TVHYFWIGAIPAMVFLGIVMMPFYYGSGVRSVPEFMLKRFGPAAHLVNAISFALAQLLIAGINLYLLGTIVHALLGWPLW
VALIVAAMIVLAYISLGGLSAAIYNEVLQFFVIVASLLPLVIIGLHRVGGWSGLKAKITAAAEAHPDVVTPAAQQLHSWP
GQALSGFGSPVMSVIGITLGLGFVLSFGYWTTNFVEVQRAMASDSLSSARKTPTIGAFPKMLVPFLTVLPGMLAAVLVPE
IARMKAGEKVAGGASGSFVQYNDSVLFLIRNLLPTGLTGVAITGLLAAFMAGMAANISAFNTVFSVDIWQHYVIKDKPDG
YYVKVGRIATVIATVVAIGTAFMASGFSNIMDYLQTLFGFFNAPLFATFILGMFWKRSTPHAGWSGLVVGTLSAVTVWVM
SLAGVFTLPGQGTAFLAATVGFVADIIVSIVVSLFTEPKPAAELVRLVYSETPKEHLVDPLEKDLPWYRRTVPLGMTVLA
ITVVLNIIF
>Mature_648_residues
AWGVCDINGSFAGQNPVTTRLSVRRCQWRCVDFAHSKCLRTQNYRVQMRSCRTGVYGSPRGDANEAVPPPHQPKGPLRTM
PLETLINAGFVDYLILLIYFVFVLGIGLAARHQVSDSLDFFLSGRSLPGWVTGLAFVSANLGAVEIMGMSANGAQIGIPT
VHYFWIGAIPAMVFLGIVMMPFYYGSGVRSVPEFMLKRFGPAAHLVNAISFALAQLLIAGINLYLLGTIVHALLGWPLWV
ALIVAAMIVLAYISLGGLSAAIYNEVLQFFVIVASLLPLVIIGLHRVGGWSGLKAKITAAAEAHPDVVTPAAQQLHSWPG
QALSGFGSPVMSVIGITLGLGFVLSFGYWTTNFVEVQRAMASDSLSSARKTPTIGAFPKMLVPFLTVLPGMLAAVLVPEI
ARMKAGEKVAGGASGSFVQYNDSVLFLIRNLLPTGLTGVAITGLLAAFMAGMAANISAFNTVFSVDIWQHYVIKDKPDGY
YVKVGRIATVIATVVAIGTAFMASGFSNIMDYLQTLFGFFNAPLFATFILGMFWKRSTPHAGWSGLVVGTLSAVTVWVMS
LAGVFTLPGQGTAFLAATVGFVADIIVSIVVSLFTEPKPAAELVRLVYSETPKEHLVDPLEKDLPWYRRTVPLGMTVLAI
TVVLNIIF

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=614, Percent_Identity=24.4299674267101, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI4507031, Length=574, Percent_Identity=27.1777003484321, Blast_Score=170, Evalue=5e-42,
Organism=Homo sapiens, GI4507033, Length=584, Percent_Identity=27.0547945205479, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI206597483, Length=538, Percent_Identity=27.8810408921933, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI17941285, Length=482, Percent_Identity=27.1784232365145, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI206597487, Length=562, Percent_Identity=26.8683274021352, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI110835708, Length=594, Percent_Identity=26.7676767676768, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI109659836, Length=478, Percent_Identity=26.5690376569038, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI109659839, Length=494, Percent_Identity=26.5182186234818, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI256985183, Length=511, Percent_Identity=22.3091976516634, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4507035, Length=203, Percent_Identity=26.6009852216749, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI167466278, Length=456, Percent_Identity=22.5877192982456, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI157671931, Length=490, Percent_Identity=19.1836734693878, Blast_Score=77, Evalue=7e-14,
Organism=Escherichia coli, GI1790113, Length=451, Percent_Identity=23.7250554323725, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24641117, Length=472, Percent_Identity=22.0338983050847, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573698, Length=487, Percent_Identity=20.9445585215606, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24645928, Length=475, Percent_Identity=21.8947368421053, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651741, Length=475, Percent_Identity=19.5789473684211, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651739, Length=476, Percent_Identity=18.0672268907563, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362918, Length=486, Percent_Identity=20.7818930041152, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 69635; Mature: 69504

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWGVCDINGSFAGQNPVTTRLSVRRCQWRCVDFAHSKCLRTQNYRVQMRSCRTGVYGSP
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
RGDANEAVPPPHQPKGPLRTMPLETLINAGFVDYLILLIYFVFVLGIGLAARHQVSDSLD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFLSGRSLPGWVTGLAFVSANLGAVEIMGMSANGAQIGIPTVHYFWIGAIPAMVFLGIVM
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHH
MPFYYGSGVRSVPEFMLKRFGPAAHLVNAISFALAQLLIAGINLYLLGTIVHALLGWPLW
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALIVAAMIVLAYISLGGLSAAIYNEVLQFFVIVASLLPLVIIGLHRVGGWSGLKAKITA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AAEAHPDVVTPAAQQLHSWPGQALSGFGSPVMSVIGITLGLGFVLSFGYWTTNFVEVQRA
CCCCCCCCCCHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MASDSLSSARKTPTIGAFPKMLVPFLTVLPGMLAAVLVPEIARMKAGEKVAGGASGSFVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
YNDSVLFLIRNLLPTGLTGVAITGLLAAFMAGMAANISAFNTVFSVDIWQHYVIKDKPDG
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
YYVKVGRIATVIATVVAIGTAFMASGFSNIMDYLQTLFGFFNAPLFATFILGMFWKRSTP
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
HAGWSGLVVGTLSAVTVWVMSLAGVFTLPGQGTAFLAATVGFVADIIVSIVVSLFTEPKP
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAELVRLVYSETPKEHLVDPLEKDLPWYRRTVPLGMTVLAITVVLNIIF
HHHHHHHHHHCCCHHHHCCHHHHCCCHHHHHCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AWGVCDINGSFAGQNPVTTRLSVRRCQWRCVDFAHSKCLRTQNYRVQMRSCRTGVYGSP
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
RGDANEAVPPPHQPKGPLRTMPLETLINAGFVDYLILLIYFVFVLGIGLAARHQVSDSLD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFLSGRSLPGWVTGLAFVSANLGAVEIMGMSANGAQIGIPTVHYFWIGAIPAMVFLGIVM
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHH
MPFYYGSGVRSVPEFMLKRFGPAAHLVNAISFALAQLLIAGINLYLLGTIVHALLGWPLW
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALIVAAMIVLAYISLGGLSAAIYNEVLQFFVIVASLLPLVIIGLHRVGGWSGLKAKITA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AAEAHPDVVTPAAQQLHSWPGQALSGFGSPVMSVIGITLGLGFVLSFGYWTTNFVEVQRA
CCCCCCCCCCHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MASDSLSSARKTPTIGAFPKMLVPFLTVLPGMLAAVLVPEIARMKAGEKVAGGASGSFVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
YNDSVLFLIRNLLPTGLTGVAITGLLAAFMAGMAANISAFNTVFSVDIWQHYVIKDKPDG
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
YYVKVGRIATVIATVVAIGTAFMASGFSNIMDYLQTLFGFFNAPLFATFILGMFWKRSTP
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
HAGWSGLVVGTLSAVTVWVMSLAGVFTLPGQGTAFLAATVGFVADIIVSIVVSLFTEPKP
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAELVRLVYSETPKEHLVDPLEKDLPWYRRTVPLGMTVLAITVVLNIIF
HHHHHHHHHHCCCHHHHCCHHHHCCCHHHHHCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]