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The map label for this gene is mtaD [H]

Identifier: 50843605

GI number: 50843605

Start: 2348935

End: 2350275

Strand: Direct

Name: mtaD [H]

Synonym: PPA2168

Alternate gene names: 50843605

Gene position: 2348935-2350275 (Clockwise)

Preceding gene: 50843604

Following gene: 50843606

Centisome position: 91.75

GC content: 63.16

Gene sequence:

>1341_bases
ATGAGCACATGGTTTTTCCCGAGCGCCCTGGTAGAGGGGCGGATTGCGCACAACGTGCGCGTCCAAAGCCAGAACGGCGT
CATCACTGCGGTGACGATAGGGGCCGAACCTCATCGACACACCTTCGATGGGGTCGCTGTGCCGGGATTCGCCAATACTC
ACTCCCATATTTTCCACCGCGGGCTGCGCGGGGCCGGGGAGGGCGAAGATTTCTGGTCCTGGCGCACCGAAATGTATCGA
CTAGCCAACCGTCTCGACCCAGACTCCTACTACCGACTGGCGCGAGCTGCCTTTGCTGAGATGGTGGCGGCCGGATACAC
CAGCGTAGGTGAGTTCCACTACGTCCATCACCAGCCTGACGGGACGCCCTATCGCGATCATGCGATGGAATTAGCCCTTG
TCAACGCCGCCATTGAAGCCGGGATTCGCATCACTGTCCTCGACACCTGCTACCTGCACGCCGGACCGGGAGCGTCCCTT
GGCGTAGACCAGAAGAGGTTTGGTGACGGTAGCGTCGAGGGGTGGTTGGAGCGTTGGCGCGCGCTGCGTGATGCTCTGCC
CGACTCCCCCTTGGTGACGGTGGGCGCAGCTCTACATTCGGTGCGGGCCGTCAGCCCCGACGAGATGGCCACAGCTGTAA
GTGGACTACCGGAACGTGTACCCATTCACATCCACGTCTCCGAGCAGCCCCGCGAGAACACCGAATGCTTGGCTGCACAT
GGCCTGACGCCGACAGCAGTGCTGGACCGAGCTGGGGTGCTCTCCGACCGCACTACCATCATCCATGCCACCCATCTGAC
CGGCGGCGACATCGCCATGATCGCGGCTTCGGATACCGTCGTCTCACTGTGTCCAACCACCGAGGCCGATCTGGGTGACG
GCATCGCGCGGGTCAAGGACCTGCAGGATGCCGGGGTGCGCATGGCAATTGGGACTGACGAGGACGTCATTACCGACCCC
TTTACCGAATTGCGGATGCTGGAATCCACTGCTCGCTTGGTCACCGGGACGCGCGGTGTCATTGGTTGTGAGGCGCTGTG
GAAAATCGGTACACGAAACGGGGTTGAGAGTCTCCGTCCGGCAGCTGAGCCGCTTCCACGCCAGACTTCCACACCCGGGC
CTGGATCCGCTGGGCTGGCCGCCGGGGACCCCGCCGATATTGTCGTCGTCGAGCCGTCATCAGCACGCCTGGCCGGGGTG
GACCCGACGCGCTGGCCCCTAGTGGCAACAGCCAATGACGTAGCGGCCACTATCGTCGCTGGGGAGTGGAACCGGCTTGA
TGCCGCAGTCGCCGAGGACCTGCGCCACGTATTAGACGAACTGAGAGGCCGTGACTCGTGA

Upstream 100 bases:

>100_bases
ATCCCACCGGGGCTTCTCACTGCCCCGCAGAATCAGCGAGTGACGCCGACTGCGAAGCCGGGGCCGAAGCGCTGCAAACC
GTGCTAGAGGAGCTCGTCAA

Downstream 100 bases:

>100_bases
GCATCGTCATCAATAACATCGGTCTGCTTGTTACCAACGATCCATCTGTCGGTACTGACGAGCTCGGACAAATCCGCAAT
GCAGCCGTCGTGATCTGCGG

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSTWFFPSALVEGRIAHNVRVQSQNGVITAVTIGAEPHRHTFDGVAVPGFANTHSHIFHRGLRGAGEGEDFWSWRTEMYR
LANRLDPDSYYRLARAAFAEMVAAGYTSVGEFHYVHHQPDGTPYRDHAMELALVNAAIEAGIRITVLDTCYLHAGPGASL
GVDQKRFGDGSVEGWLERWRALRDALPDSPLVTVGAALHSVRAVSPDEMATAVSGLPERVPIHIHVSEQPRENTECLAAH
GLTPTAVLDRAGVLSDRTTIIHATHLTGGDIAMIAASDTVVSLCPTTEADLGDGIARVKDLQDAGVRMAIGTDEDVITDP
FTELRMLESTARLVTGTRGVIGCEALWKIGTRNGVESLRPAAEPLPRQTSTPGPGSAGLAAGDPADIVVVEPSSARLAGV
DPTRWPLVATANDVAATIVAGEWNRLDAAVAEDLRHVLDELRGRDS

Sequences:

>Translated_446_residues
MSTWFFPSALVEGRIAHNVRVQSQNGVITAVTIGAEPHRHTFDGVAVPGFANTHSHIFHRGLRGAGEGEDFWSWRTEMYR
LANRLDPDSYYRLARAAFAEMVAAGYTSVGEFHYVHHQPDGTPYRDHAMELALVNAAIEAGIRITVLDTCYLHAGPGASL
GVDQKRFGDGSVEGWLERWRALRDALPDSPLVTVGAALHSVRAVSPDEMATAVSGLPERVPIHIHVSEQPRENTECLAAH
GLTPTAVLDRAGVLSDRTTIIHATHLTGGDIAMIAASDTVVSLCPTTEADLGDGIARVKDLQDAGVRMAIGTDEDVITDP
FTELRMLESTARLVTGTRGVIGCEALWKIGTRNGVESLRPAAEPLPRQTSTPGPGSAGLAAGDPADIVVVEPSSARLAGV
DPTRWPLVATANDVAATIVAGEWNRLDAAVAEDLRHVLDELRGRDS
>Mature_445_residues
STWFFPSALVEGRIAHNVRVQSQNGVITAVTIGAEPHRHTFDGVAVPGFANTHSHIFHRGLRGAGEGEDFWSWRTEMYRL
ANRLDPDSYYRLARAAFAEMVAAGYTSVGEFHYVHHQPDGTPYRDHAMELALVNAAIEAGIRITVLDTCYLHAGPGASLG
VDQKRFGDGSVEGWLERWRALRDALPDSPLVTVGAALHSVRAVSPDEMATAVSGLPERVPIHIHVSEQPRENTECLAAHG
LTPTAVLDRAGVLSDRTTIIHATHLTGGDIAMIAASDTVVSLCPTTEADLGDGIARVKDLQDAGVRMAIGTDEDVITDPF
TELRMLESTARLVTGTRGVIGCEALWKIGTRNGVESLRPAAEPLPRQTSTPGPGSAGLAAGDPADIVVVEPSSARLAGVD
PTRWPLVATANDVAATIVAGEWNRLDAAVAEDLRHVLDELRGRDS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=363, Percent_Identity=31.9559228650138, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47714; Mature: 47583

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTWFFPSALVEGRIAHNVRVQSQNGVITAVTIGAEPHRHTFDGVAVPGFANTHSHIFHR
CCCCCCCHHHHCCHHHCEEEEECCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHH
GLRGAGEGEDFWSWRTEMYRLANRLDPDSYYRLARAAFAEMVAAGYTSVGEFHYVHHQPD
HCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GTPYRDHAMELALVNAAIEAGIRITVLDTCYLHAGPGASLGVDQKRFGDGSVEGWLERWR
CCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHH
ALRDALPDSPLVTVGAALHSVRAVSPDEMATAVSGLPERVPIHIHVSEQPRENTECLAAH
HHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEC
GLTPTAVLDRAGVLSDRTTIIHATHLTGGDIAMIAASDTVVSLCPTTEADLGDGIARVKD
CCCHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHH
LQDAGVRMAIGTDEDVITDPFTELRMLESTARLVTGTRGVIGCEALWKIGTRNGVESLRP
HHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCC
AAEPLPRQTSTPGPGSAGLAAGDPADIVVVEPSSARLAGVDPTRWPLVATANDVAATIVA
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCEEEECCCEEEEEEE
GEWNRLDAAVAEDLRHVLDELRGRDS
CCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STWFFPSALVEGRIAHNVRVQSQNGVITAVTIGAEPHRHTFDGVAVPGFANTHSHIFHR
CCCCCCHHHHCCHHHCEEEEECCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHH
GLRGAGEGEDFWSWRTEMYRLANRLDPDSYYRLARAAFAEMVAAGYTSVGEFHYVHHQPD
HCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GTPYRDHAMELALVNAAIEAGIRITVLDTCYLHAGPGASLGVDQKRFGDGSVEGWLERWR
CCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHH
ALRDALPDSPLVTVGAALHSVRAVSPDEMATAVSGLPERVPIHIHVSEQPRENTECLAAH
HHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEC
GLTPTAVLDRAGVLSDRTTIIHATHLTGGDIAMIAASDTVVSLCPTTEADLGDGIARVKD
CCCHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHH
LQDAGVRMAIGTDEDVITDPFTELRMLESTARLVTGTRGVIGCEALWKIGTRNGVESLRP
HHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCC
AAEPLPRQTSTPGPGSAGLAAGDPADIVVVEPSSARLAGVDPTRWPLVATANDVAATIVA
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCEEEECCCEEEEEEE
GEWNRLDAAVAEDLRHVLDELRGRDS
CCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA