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The map label for this gene is appB [H]

Identifier: 50843508

GI number: 50843508

Start: 2244772

End: 2245731

Strand: Direct

Name: appB [H]

Synonym: PPA2064

Alternate gene names: 50843508

Gene position: 2244772-2245731 (Clockwise)

Preceding gene: 50843507

Following gene: 50843509

Centisome position: 87.68

GC content: 57.81

Gene sequence:

>960_bases
ATGACGCGATACATCGCGCAACGCGTTTTTCAAGCGCTGATAGTGCTGTTGCTCGTCACGCTTATCACTTTCTCCATCCT
TCACGCACTTCCAGGCGGAGCAGCTCGCTCGGCTTTGGGACTGGACGCCACCCAAGCGCAGATCGACGCATACAACCATC
AGATGGGTTACGACCAACCCTTATGGAAGCAGTACTTCGGCTATCTGATCCAGATCTTCCATGGCGAATTCGGACACTCT
TTCCGACTCAACATGCCGGTTGCCGACGCGATCGGTCAGCGGCTTCCTAAGACGATTGTCCTCAGTCTCATGTCGGCAGT
CGTCGCCATCCTCCTCGCGATCCCTATCGGCGCTATCCAAGCCGTCAAGCGCAACCGCACGGCTGACTACACTCTCACCG
TCATCGCCATGCTGGCATATTCCACACCATTGTTCTTCCTGGGCCTCGTTCTCATCATCCTCTTCTCACAGGTGTGGCCG
ATCTTCCCACCAGAAGCGCCACAAGGGTTCAGCGTCGGAGAAGTTCTTAGCCAAGGGCGATCGCTCGTGCTGCCCACCAC
GACGCTCGCCATCGTCACGCTGGCCGTGTACGCGCGCTACATGCGTTCCTCGATGATTGACAACCTCGAGGAAAACTACA
TCCGCACCGCCCGCAGTAAGGGAATCACCGAGACAAGAGTCGTCATCGTTCATGCCCTGCGCAACTCGCTGTTTCCGATC
ATCACCCTACTCGGCATGCAGTTGCCGGCCTTGTTCTCCGGTGCGCTGGTAGTGGAGTCGCTGTTCAACTACCCCGGCAT
GGGTCTGTTGTTCTGGCAGGCGGCCCAGTTCCGCGACTACCCCATCCTGCTAGCAGTCACCATCATCATCTCAATGGCCA
CCGTGCTCGGCGCCCTCATCGCAGACATCCTCTATGCCGTCGTCGATCCGCGGATTCGTTACGGAGGAGCAGACCGATGA

Upstream 100 bases:

>100_bases
GCCCACGTTACTGACCCCGCCCGTTTCACACGGCGTCACCGGGTCGCCCCGGTGACGCCACCCCAACGTCCCAATCACCC
ATCTCAGGAGGGAGCAAAGG

Downstream 100 bases:

>100_bases
GCACCGAGATCGCTATTCCCGATCCTCAGAGCCGACGTCCCGAATCTGCCCGTCCCATGCGTCCCGGCACAGCGCGACGG
ACCAGCAGACGCACCAGCCT

Product: dipeptide transport system permease protein DppB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTRYIAQRVFQALIVLLLVTLITFSILHALPGGAARSALGLDATQAQIDAYNHQMGYDQPLWKQYFGYLIQIFHGEFGHS
FRLNMPVADAIGQRLPKTIVLSLMSAVVAILLAIPIGAIQAVKRNRTADYTLTVIAMLAYSTPLFFLGLVLIILFSQVWP
IFPPEAPQGFSVGEVLSQGRSLVLPTTTLAIVTLAVYARYMRSSMIDNLEENYIRTARSKGITETRVVIVHALRNSLFPI
ITLLGMQLPALFSGALVVESLFNYPGMGLLFWQAAQFRDYPILLAVTIIISMATVLGALIADILYAVVDPRIRYGGADR

Sequences:

>Translated_319_residues
MTRYIAQRVFQALIVLLLVTLITFSILHALPGGAARSALGLDATQAQIDAYNHQMGYDQPLWKQYFGYLIQIFHGEFGHS
FRLNMPVADAIGQRLPKTIVLSLMSAVVAILLAIPIGAIQAVKRNRTADYTLTVIAMLAYSTPLFFLGLVLIILFSQVWP
IFPPEAPQGFSVGEVLSQGRSLVLPTTTLAIVTLAVYARYMRSSMIDNLEENYIRTARSKGITETRVVIVHALRNSLFPI
ITLLGMQLPALFSGALVVESLFNYPGMGLLFWQAAQFRDYPILLAVTIIISMATVLGALIADILYAVVDPRIRYGGADR
>Mature_318_residues
TRYIAQRVFQALIVLLLVTLITFSILHALPGGAARSALGLDATQAQIDAYNHQMGYDQPLWKQYFGYLIQIFHGEFGHSF
RLNMPVADAIGQRLPKTIVLSLMSAVVAILLAIPIGAIQAVKRNRTADYTLTVIAMLAYSTPLFFLGLVLIILFSQVWPI
FPPEAPQGFSVGEVLSQGRSLVLPTTTLAIVTLAVYARYMRSSMIDNLEENYIRTARSKGITETRVVIVHALRNSLFPII
TLLGMQLPALFSGALVVESLFNYPGMGLLFWQAAQFRDYPILLAVTIIISMATVLGALIADILYAVVDPRIRYGGADR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=314, Percent_Identity=37.8980891719745, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=33.4310850439883, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=37.3493975903614, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1787497, Length=316, Percent_Identity=32.5949367088608, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=31.6455696202532, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788504, Length=370, Percent_Identity=25.6756756756757, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=26.4705882352941, Blast_Score=118, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35161; Mature: 35030

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYIAQRVFQALIVLLLVTLITFSILHALPGGAARSALGLDATQAQIDAYNHQMGYDQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCH
LWKQYFGYLIQIFHGEFGHSFRLNMPVADAIGQRLPKTIVLSLMSAVVAILLAIPIGAIQ
HHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKRNRTADYTLTVIAMLAYSTPLFFLGLVLIILFSQVWPIFPPEAPQGFSVGEVLSQGR
HHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC
SLVLPTTTLAIVTLAVYARYMRSSMIDNLEENYIRTARSKGITETRVVIVHALRNSLFPI
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ITLLGMQLPALFSGALVVESLFNYPGMGLLFWQAAQFRDYPILLAVTIIISMATVLGALI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ADILYAVVDPRIRYGGADR
HHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure 
TRYIAQRVFQALIVLLLVTLITFSILHALPGGAARSALGLDATQAQIDAYNHQMGYDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCH
LWKQYFGYLIQIFHGEFGHSFRLNMPVADAIGQRLPKTIVLSLMSAVVAILLAIPIGAIQ
HHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKRNRTADYTLTVIAMLAYSTPLFFLGLVLIILFSQVWPIFPPEAPQGFSVGEVLSQGR
HHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC
SLVLPTTTLAIVTLAVYARYMRSSMIDNLEENYIRTARSKGITETRVVIVHALRNSLFPI
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ITLLGMQLPALFSGALVVESLFNYPGMGLLFWQAAQFRDYPILLAVTIIISMATVLGALI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ADILYAVVDPRIRYGGADR
HHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]