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The map label for this gene is xylR [H]

Identifier: 50843506

GI number: 50843506

Start: 2241476

End: 2242669

Strand: Reverse

Name: xylR [H]

Synonym: PPA2062

Alternate gene names: 50843506

Gene position: 2242669-2241476 (Counterclockwise)

Preceding gene: 50843514

Following gene: 50843505

Centisome position: 87.6

GC content: 60.13

Gene sequence:

>1194_bases
ATGACAGATATTGAGCTCACCAACCTTGGCGCGACGGGCATGAATGGGCACACTGACGATCAGCTGGGCAGCGCGCCTGG
GCAGCGAGTCATCAAGATTCTTCGAAAAACGCCGGGTATGACTCGCGCCGAGATCGCCGAGAGCACTTCCATGCCACGTT
CCACGGTGAGCGCGGCGGTGCGACACCTGCTCGAGTCGCGAGTCGTTGAAGAGTACGCGTGCGCAGATTCCACCGGTGGT
CGTCGTCCCACTAAATTGCGCGTTGCACCAGCAGTCGGCAATGCCTTTGTTGCAGAACTTGGCCAGCATCATGCCCGGTT
GGCAATAGCGTCTCGGGAGGGCGAGCTACTCGCTACCGACGACATCAAGATAAACATAGAGATCGGTCCGGAGAAGACGA
TCAAAGCCTTGGCCAAGGGGTGGCACAAGCTTGGTGACGAGATCCCTGGAGCGGTGGTTTCAGCCGGCTTGGCGGTACCC
GGCCCGGTGGACGGTAGTGGTCACGTCGTTGGGGCAGCGCGGATGCCTGGGTGGAGTGGCAAAGACATCGCCGGCATGTT
GGCACAGGAACTCGCGGTGCCATCAGTTATCGAGAATGACGCTCGTGCCGCGACAATCGGGGAGTGGAACTGCCGCGGAC
GGCACCGGGACTCCTGCATCTACGTTAAAGCTGGCACCGGCATAGGTGCTGGTTGGGTCAGCGGCGGGGTCGCTTACCGA
GGCTCACGCGGTCTTGCTGGCGACATCACCCATCTGCGGGTGCATACCGATAACCCCCTACCGTGTACCTGTGGTAACTC
CGGGTGTTTGGAGACGGTGGCATCGGGGGCTGCGATCCTACGGCAGCTGGGCCGTTTGGGCTCGTCCATTTCCACAACCT
CACAGTTGGTGACTGCCGAGAACAGCGGCGATCCCCAGGCGGTTTCCTTAGTGCGTGACGCCGGAATGCGTCTTGGTGAG
GTGCTTTCCAACCTTGTTAACTTCCTCAACCCGGTTCGCATCGTGTTGGGCGGCTCAATGTCGCAGATGGGTTCTTTGCT
CGCTGGCGTACGCAGTGAACTGTACGAGCGCTGTTTGCCCATGTGCACCGAGGATCTCGTGATCGAGACCTCTGCTTGCG
GAGCCGATGCCCCGCTCATCGGCATGTCGATACTTGACTCTCATATGCCCATCTCACAGGAAGGCAATCGCTGA

Upstream 100 bases:

>100_bases
AATAATCTAGCTTTTATCACTTTTGCTACACATATCTCCGGACGCGGGCATACTGTGGGCCGAGACGTCGGGCAGGCACG
ATGACGGATTGAGGAAGCTG

Downstream 100 bases:

>100_bases
TGATACGTATAGCCATTTGTGGACTTCATATTGAATCGAGTACTTTCACCCCCTACATGAGCACGGCCGCTGACTTCACG
CAGCGTCGCGGCCAGACACT

Product: ROK family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTDIELTNLGATGMNGHTDDQLGSAPGQRVIKILRKTPGMTRAEIAESTSMPRSTVSAAVRHLLESRVVEEYACADSTGG
RRPTKLRVAPAVGNAFVAELGQHHARLAIASREGELLATDDIKINIEIGPEKTIKALAKGWHKLGDEIPGAVVSAGLAVP
GPVDGSGHVVGAARMPGWSGKDIAGMLAQELAVPSVIENDARAATIGEWNCRGRHRDSCIYVKAGTGIGAGWVSGGVAYR
GSRGLAGDITHLRVHTDNPLPCTCGNSGCLETVASGAAILRQLGRLGSSISTTSQLVTAENSGDPQAVSLVRDAGMRLGE
VLSNLVNFLNPVRIVLGGSMSQMGSLLAGVRSELYERCLPMCTEDLVIETSACGADAPLIGMSILDSHMPISQEGNR

Sequences:

>Translated_397_residues
MTDIELTNLGATGMNGHTDDQLGSAPGQRVIKILRKTPGMTRAEIAESTSMPRSTVSAAVRHLLESRVVEEYACADSTGG
RRPTKLRVAPAVGNAFVAELGQHHARLAIASREGELLATDDIKINIEIGPEKTIKALAKGWHKLGDEIPGAVVSAGLAVP
GPVDGSGHVVGAARMPGWSGKDIAGMLAQELAVPSVIENDARAATIGEWNCRGRHRDSCIYVKAGTGIGAGWVSGGVAYR
GSRGLAGDITHLRVHTDNPLPCTCGNSGCLETVASGAAILRQLGRLGSSISTTSQLVTAENSGDPQAVSLVRDAGMRLGE
VLSNLVNFLNPVRIVLGGSMSQMGSLLAGVRSELYERCLPMCTEDLVIETSACGADAPLIGMSILDSHMPISQEGNR
>Mature_396_residues
TDIELTNLGATGMNGHTDDQLGSAPGQRVIKILRKTPGMTRAEIAESTSMPRSTVSAAVRHLLESRVVEEYACADSTGGR
RPTKLRVAPAVGNAFVAELGQHHARLAIASREGELLATDDIKINIEIGPEKTIKALAKGWHKLGDEIPGAVVSAGLAVPG
PVDGSGHVVGAARMPGWSGKDIAGMLAQELAVPSVIENDARAATIGEWNCRGRHRDSCIYVKAGTGIGAGWVSGGVAYRG
SRGLAGDITHLRVHTDNPLPCTCGNSGCLETVASGAAILRQLGRLGSSISTTSQLVTAENSGDPQAVSLVRDAGMRLGEV
LSNLVNFLNPVRIVLGGSMSQMGSLLAGVRSELYERCLPMCTEDLVIETSACGADAPLIGMSILDSHMPISQEGNR

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=272, Percent_Identity=28.3088235294118, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI298566315, Length=272, Percent_Identity=28.3088235294118, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI190014632, Length=272, Percent_Identity=28.3088235294118, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4885285, Length=272, Percent_Identity=28.3088235294118, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786891, Length=352, Percent_Identity=26.1363636363636, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082127, Length=227, Percent_Identity=29.9559471365639, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787878, Length=412, Percent_Identity=26.4563106796117, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081733, Length=242, Percent_Identity=28.9256198347107, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787363, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 41350; Mature: 41218

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIELTNLGATGMNGHTDDQLGSAPGQRVIKILRKTPGMTRAEIAESTSMPRSTVSAAV
CCCCEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHH
RHLLESRVVEEYACADSTGGRRPTKLRVAPAVGNAFVAELGQHHARLAIASREGELLATD
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCEEEEC
DIKINIEIGPEKTIKALAKGWHKLGDEIPGAVVSAGLAVPGPVDGSGHVVGAARMPGWSG
CEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEECCCCCCCC
KDIAGMLAQELAVPSVIENDARAATIGEWNCRGRHRDSCIYVKAGTGIGAGWVSGGVAYR
CHHHHHHHHHHHCCHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCHHHCCCEEEC
GSRGLAGDITHLRVHTDNPLPCTCGNSGCLETVASGAAILRQLGRLGSSISTTSQLVTAE
CCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEC
NSGDPQAVSLVRDAGMRLGEVLSNLVNFLNPVRIVLGGSMSQMGSLLAGVRSELYERCLP
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MCTEDLVIETSACGADAPLIGMSILDSHMPISQEGNR
HCCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDIELTNLGATGMNGHTDDQLGSAPGQRVIKILRKTPGMTRAEIAESTSMPRSTVSAAV
CCCEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHH
RHLLESRVVEEYACADSTGGRRPTKLRVAPAVGNAFVAELGQHHARLAIASREGELLATD
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCEEEEC
DIKINIEIGPEKTIKALAKGWHKLGDEIPGAVVSAGLAVPGPVDGSGHVVGAARMPGWSG
CEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEECCCCCCCC
KDIAGMLAQELAVPSVIENDARAATIGEWNCRGRHRDSCIYVKAGTGIGAGWVSGGVAYR
CHHHHHHHHHHHCCHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCHHHCCCEEEC
GSRGLAGDITHLRVHTDNPLPCTCGNSGCLETVASGAAILRQLGRLGSSISTTSQLVTAE
CCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEC
NSGDPQAVSLVRDAGMRLGEVLSNLVNFLNPVRIVLGGSMSQMGSLLAGVRSELYERCLP
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MCTEDLVIETSACGADAPLIGMSILDSHMPISQEGNR
HCCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]