| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is ppdK [H]
Identifier: 50843492
GI number: 50843492
Start: 2221987
End: 2224638
Strand: Reverse
Name: ppdK [H]
Synonym: PPA2048
Alternate gene names: 50843492
Gene position: 2224638-2221987 (Counterclockwise)
Preceding gene: 50843493
Following gene: 50843491
Centisome position: 86.89
GC content: 60.86
Gene sequence:
>2652_bases ATGACTGACCGTTACGTGTACGACTTGTCCGAGGGCAGTGCGGAAATGAAACCGCTGCTCGGCGGCAAGGGCGCAGGAGT TGCCGAGATGAAGCGTCTCGGCGTCCCGGTGCCCGACGGGTTTACCGTCACCACCGAAGCCTGCGTGGACACCATGACGA GGAAGGGTGAGTGGCCCGAAGATCTGGAGTCCCAAGTATGGGACGGCCTTAAGCGACTTGAGGAGCGCACCGGTCGCGTC CTCGGTGACGACAAGAAGCCGCTGCTGGTCTCCGTGCGATCTGGCGCCGTGATCTCGATGCCCGGCATGATGGACACCAT CCTCAACCTCGGCATCTCTGACGACACCGTTGAGGCCATCGCTAAGGAAGCTGGCAATGAGCGGTTTGCGTGGGACTGCT ACCGCCGCTTCATCCAAATGTACGGCGAGGTCGTCGAGGGTATCGACGCTCACATTTACGAGGATGCCCTGACCGCCCTT AAAGAGAAGAAAGGCGTCGAGTCCGACACCGATCTGAGTGCCGATGACCTCAAGGGTCTCGTTGACACCTTCAAGAAGCT GTCGAACGAGCAGCTCGGTGGGAACTGGACAACCGATCCGCGTGAGCAACTGATGCGTGCCGTTGACGCCGTGTTCCGTT CCTGGCTCAACCCGCGTGCCTTCGTCTACCGCAAAGCCAACAAGATTCCCGACGACTTGGGTACCGCCGTCAATGTCATG CAGATGGTCTTCGGCAACCGTGGCGACACGTCCGCTACCGGTGTCTGCTTCACCCGTAACCCTGCCACCGGTGAGAAGGA GCTCTATGGTGAGTTCCTCGTTAATGCTCAGGGCGAGGACGTCGTTGCTGGTATCCGCACCCCGCGTTCCCTCGCCGAGA TGGAGGAAGTGCTTCCGGAGGCCTACCACGACCTCATCGACACCATGAAGAAGATGGAGTCGCACTACCGCGACATGCAG GACATGGAGTTCACCGTCGAGAATGGCAAGCTCTACCTGCTGCAGACCCGTAACGGTAAGCGCACTGCTGCTGCGGCCCT CAAGGTGGCTCGCGACCTCGTTGACGAGGGGGTCATCACCAAGGAAGAAGCCCTCATGCGGATCGAGCCGGCTCAGCTTG ATCAGCTCTTGCACGAGGCGATCGACCCGGACCACAGCGAGCAGCCAGTTGCCGAGGGCTTGCCGGCCTCCCCGGGTGCT GCTGTTGGTGAGGCTGTCTTCGACGCTGACGTTGCTGCTGAGCGTGGCGCTAAGGGCGAGAAGGTTGTCCTCATTCGCTT TGAGACCACCCCTGACGACATTCACGGCGTCATCGTCAGCCAGGGCGTTCTGACTGCCCACGGTGGCATGACTTCCCACG CGGCCGTTGTCGCCCGTGGCATGGGCAAGCCCTGCGTTGCCGGCGCTCGTGGCATCAAGATTGACGCTAAGGCCGCCACC CTGACCATTGGTGACACCGTCATCCACGAGGGGGACATGATCACCCTTGACGGATCCACTGGTGAGGTCTTCGCCAGCGG CCTCAAGCTCATTCCACCGCAGATCAACGCGGACTTCCAGGAGGTGCTCTCCTGGGCCGACGAAATCCGTCGCCTAGGTG TTGAGGCCAACGCCGACAATGCCACCGACGCTGCCAAGGCTCGCGAGCTGGGTGCCGAGGGCATCGGGTTGTGCCGCACC GAGCACATGTTCTTCGGTGCTGATCGTCTGCCGGCCATGCACGAGATGATCACCGCGGACACTCCGGAGGAGCGTCAGGC AGCCGTCGACAAGATCCTGCCTATGCAGCAGGATGACTTTGAGGGTATCTTCACCGCGATGAAGGGCCTGCCCGTCACTG TCCGGTTGCTTGACCCGCCTCTTCACGAGTTCCTGCCGAACCTCGTTGAGCAGTCCCTCAAGGTTCAGAAGATGGAGAAC CAGGGTGCTGACGCTGGTGAGCTCGACAAGGAACGTCGTCTGTTGGCCCAGGTGAAGAAGCTGCACGAGCAGAACCCGAT GCTCGGTACCCGTGGTTGCCGTCTTGGCATGCTCTACCCGGAGATTCCTGACATGCAGGCCCGCGCGATTATTCGCGCTG TCCTGTCGGTGCTCAAGAAGGAGGGTGAGACCGTCCAGATCCACATCATGATCCCGTTGGTCTTCACCCCAATCGAGCTT GAGACCCATCGTCGGATCGTTCAGCAGGCCATCGATGAAGAGTTCGAGTCTGCCGGTACCAAGGTCGACGTCAAGATCGG GACCATGATCGAGTTGCCGCGTGCCGCCCTGGTTGCCGACAAGATTGCCGAAGTTGCTGACTTCTTCAGCTTCGGTACCA ACGACCTGACCCAGACCACGCTGGGCATCAGCCGTGACGACGCCGAGAATGGCTTCCTCACTGAGTACCTGCGCACTAAG GTCCTCAAGGACAACCCGTTCGCCTCGATCGACCAAGAGGGCGTCGGCCAGCTCGTTGCCGGAGCCGTTGAAAAGGGCCG CAAGACTAATCCAGAGCTGTCTGTCGGGGTCTGCGGTGAGCACGGTGGCGATCCGGACTCGATCCACTTCTTCAACAAGA CTGGGCTCGATTACGTGTCCTGCTCGCCGTTCCGTGTACCGATCGCGCGGTTCGCTGCGGCCCAGGCAGTCATCTCCCAG CAGGAGAAGTGA
Upstream 100 bases:
>100_bases GGCCCAACTGAGGGCTGGGCCTCGGGTCCGCTACGCAGTCGCACGGGCCCGATCGCCGTGATTTGCTGAACAGGCTGACA CAGATCGAAGGAGATCAGTC
Downstream 100 bases:
>100_bases TCTGCCATCGCATTATTGATGTGTGATTCTGCGGCCTCTCCATCGTGGTAGAGAGGCCGCATACACGCCGGTATGTACCG GCTACTTCGCATCCGATTGG
Product: pyruvate phosphate dikinase
Products: NA
Alternate protein names: Pyruvate, orthophosphate dikinase [H]
Number of amino acids: Translated: 883; Mature: 882
Protein sequence:
>883_residues MTDRYVYDLSEGSAEMKPLLGGKGAGVAEMKRLGVPVPDGFTVTTEACVDTMTRKGEWPEDLESQVWDGLKRLEERTGRV LGDDKKPLLVSVRSGAVISMPGMMDTILNLGISDDTVEAIAKEAGNERFAWDCYRRFIQMYGEVVEGIDAHIYEDALTAL KEKKGVESDTDLSADDLKGLVDTFKKLSNEQLGGNWTTDPREQLMRAVDAVFRSWLNPRAFVYRKANKIPDDLGTAVNVM QMVFGNRGDTSATGVCFTRNPATGEKELYGEFLVNAQGEDVVAGIRTPRSLAEMEEVLPEAYHDLIDTMKKMESHYRDMQ DMEFTVENGKLYLLQTRNGKRTAAAALKVARDLVDEGVITKEEALMRIEPAQLDQLLHEAIDPDHSEQPVAEGLPASPGA AVGEAVFDADVAAERGAKGEKVVLIRFETTPDDIHGVIVSQGVLTAHGGMTSHAAVVARGMGKPCVAGARGIKIDAKAAT LTIGDTVIHEGDMITLDGSTGEVFASGLKLIPPQINADFQEVLSWADEIRRLGVEANADNATDAAKARELGAEGIGLCRT EHMFFGADRLPAMHEMITADTPEERQAAVDKILPMQQDDFEGIFTAMKGLPVTVRLLDPPLHEFLPNLVEQSLKVQKMEN QGADAGELDKERRLLAQVKKLHEQNPMLGTRGCRLGMLYPEIPDMQARAIIRAVLSVLKKEGETVQIHIMIPLVFTPIEL ETHRRIVQQAIDEEFESAGTKVDVKIGTMIELPRAALVADKIAEVADFFSFGTNDLTQTTLGISRDDAENGFLTEYLRTK VLKDNPFASIDQEGVGQLVAGAVEKGRKTNPELSVGVCGEHGGDPDSIHFFNKTGLDYVSCSPFRVPIARFAAAQAVISQ QEK
Sequences:
>Translated_883_residues MTDRYVYDLSEGSAEMKPLLGGKGAGVAEMKRLGVPVPDGFTVTTEACVDTMTRKGEWPEDLESQVWDGLKRLEERTGRV LGDDKKPLLVSVRSGAVISMPGMMDTILNLGISDDTVEAIAKEAGNERFAWDCYRRFIQMYGEVVEGIDAHIYEDALTAL KEKKGVESDTDLSADDLKGLVDTFKKLSNEQLGGNWTTDPREQLMRAVDAVFRSWLNPRAFVYRKANKIPDDLGTAVNVM QMVFGNRGDTSATGVCFTRNPATGEKELYGEFLVNAQGEDVVAGIRTPRSLAEMEEVLPEAYHDLIDTMKKMESHYRDMQ DMEFTVENGKLYLLQTRNGKRTAAAALKVARDLVDEGVITKEEALMRIEPAQLDQLLHEAIDPDHSEQPVAEGLPASPGA AVGEAVFDADVAAERGAKGEKVVLIRFETTPDDIHGVIVSQGVLTAHGGMTSHAAVVARGMGKPCVAGARGIKIDAKAAT LTIGDTVIHEGDMITLDGSTGEVFASGLKLIPPQINADFQEVLSWADEIRRLGVEANADNATDAAKARELGAEGIGLCRT EHMFFGADRLPAMHEMITADTPEERQAAVDKILPMQQDDFEGIFTAMKGLPVTVRLLDPPLHEFLPNLVEQSLKVQKMEN QGADAGELDKERRLLAQVKKLHEQNPMLGTRGCRLGMLYPEIPDMQARAIIRAVLSVLKKEGETVQIHIMIPLVFTPIEL ETHRRIVQQAIDEEFESAGTKVDVKIGTMIELPRAALVADKIAEVADFFSFGTNDLTQTTLGISRDDAENGFLTEYLRTK VLKDNPFASIDQEGVGQLVAGAVEKGRKTNPELSVGVCGEHGGDPDSIHFFNKTGLDYVSCSPFRVPIARFAAAQAVISQ QEK >Mature_882_residues TDRYVYDLSEGSAEMKPLLGGKGAGVAEMKRLGVPVPDGFTVTTEACVDTMTRKGEWPEDLESQVWDGLKRLEERTGRVL GDDKKPLLVSVRSGAVISMPGMMDTILNLGISDDTVEAIAKEAGNERFAWDCYRRFIQMYGEVVEGIDAHIYEDALTALK EKKGVESDTDLSADDLKGLVDTFKKLSNEQLGGNWTTDPREQLMRAVDAVFRSWLNPRAFVYRKANKIPDDLGTAVNVMQ MVFGNRGDTSATGVCFTRNPATGEKELYGEFLVNAQGEDVVAGIRTPRSLAEMEEVLPEAYHDLIDTMKKMESHYRDMQD MEFTVENGKLYLLQTRNGKRTAAAALKVARDLVDEGVITKEEALMRIEPAQLDQLLHEAIDPDHSEQPVAEGLPASPGAA VGEAVFDADVAAERGAKGEKVVLIRFETTPDDIHGVIVSQGVLTAHGGMTSHAAVVARGMGKPCVAGARGIKIDAKAATL TIGDTVIHEGDMITLDGSTGEVFASGLKLIPPQINADFQEVLSWADEIRRLGVEANADNATDAAKARELGAEGIGLCRTE HMFFGADRLPAMHEMITADTPEERQAAVDKILPMQQDDFEGIFTAMKGLPVTVRLLDPPLHEFLPNLVEQSLKVQKMENQ GADAGELDKERRLLAQVKKLHEQNPMLGTRGCRLGMLYPEIPDMQARAIIRAVLSVLKKEGETVQIHIMIPLVFTPIELE THRRIVQQAIDEEFESAGTKVDVKIGTMIELPRAALVADKIAEVADFFSFGTNDLTQTTLGISRDDAENGFLTEYLRTKV LKDNPFASIDQEGVGQLVAGAVEKGRKTNPELSVGVCGEHGGDPDSIHFFNKTGLDYVSCSPFRVPIARFAAAQAVISQQ EK
Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]
COG id: COG0574
COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PEP-utilizing enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1788756, Length=465, Percent_Identity=26.0215053763441, Blast_Score=120, Evalue=4e-28, Organism=Escherichia coli, GI1789193, Length=471, Percent_Identity=23.9915074309979, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI1788726, Length=453, Percent_Identity=24.0618101545254, Blast_Score=87, Evalue=6e-18, Organism=Escherichia coli, GI1787994, Length=929, Percent_Identity=23.2508073196986, Blast_Score=85, Evalue=2e-17, Organism=Escherichia coli, GI48994992, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=5e-13,
Paralogues:
None
Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013815 - InterPro: IPR013816 - InterPro: IPR008279 - InterPro: IPR018274 - InterPro: IPR023151 - InterPro: IPR000121 - InterPro: IPR002192 - InterPro: IPR010121 - InterPro: IPR015813 [H]
Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]
EC number: =2.7.9.1 [H]
Molecular weight: Translated: 96476; Mature: 96345
Theoretical pI: Translated: 4.61; Mature: 4.61
Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDRYVYDLSEGSAEMKPLLGGKGAGVAEMKRLGVPVPDGFTVTTEACVDTMTRKGEWPE CCCCEEEECCCCCCHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCH DLESQVWDGLKRLEERTGRVLGDDKKPLLVSVRSGAVISMPGMMDTILNLGISDDTVEAI HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCHHHHHHHHCCCCHHHHHHH AKEAGNERFAWDCYRRFIQMYGEVVEGIDAHIYEDALTALKEKKGVESDTDLSADDLKGL HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH VDTFKKLSNEQLGGNWTTDPREQLMRAVDAVFRSWLNPRAFVYRKANKIPDDLGTAVNVM HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHH QMVFGNRGDTSATGVCFTRNPATGEKELYGEFLVNAQGEDVVAGIRTPRSLAEMEEVLPE HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHH AYHDLIDTMKKMESHYRDMQDMEFTVENGKLYLLQTRNGKRTAAAALKVARDLVDEGVIT HHHHHHHHHHHHHHHHCCHHHCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC KEEALMRIEPAQLDQLLHEAIDPDHSEQPVAEGLPASPGAAVGEAVFDADVAAERGAKGE HHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC KVVLIRFETTPDDIHGVIVSQGVLTAHGGMTSHAAVVARGMGKPCVAGARGIKIDAKAAT EEEEEEEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCEEE LTIGDTVIHEGDMITLDGSTGEVFASGLKLIPPQINADFQEVLSWADEIRRLGVEANADN EEECCCEEECCCEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC ATDAAKARELGAEGIGLCRTEHMFFGADRLPAMHEMITADTPEERQAAVDKILPMQQDDF CHHHHHHHHHCCCCCCCEEHHHHEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHH EGIFTAMKGLPVTVRLLDPPLHEFLPNLVEQSLKVQKMENQGADAGELDKERRLLAQVKK HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH LHEQNPMLGTRGCRLGMLYPEIPDMQARAIIRAVLSVLKKEGETVQIHIMIPLVFTPIEL HHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCH ETHRRIVQQAIDEEFESAGTKVDVKIGTMIELPRAALVADKIAEVADFFSFGTNDLTQTT HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHH LGISRDDAENGFLTEYLRTKVLKDNPFASIDQEGVGQLVAGAVEKGRKTNPELSVGVCGE CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC HGGDPDSIHFFNKTGLDYVSCSPFRVPIARFAAAQAVISQQEK CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure TDRYVYDLSEGSAEMKPLLGGKGAGVAEMKRLGVPVPDGFTVTTEACVDTMTRKGEWPE CCCEEEECCCCCCHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCH DLESQVWDGLKRLEERTGRVLGDDKKPLLVSVRSGAVISMPGMMDTILNLGISDDTVEAI HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCHHHHHHHHCCCCHHHHHHH AKEAGNERFAWDCYRRFIQMYGEVVEGIDAHIYEDALTALKEKKGVESDTDLSADDLKGL HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH VDTFKKLSNEQLGGNWTTDPREQLMRAVDAVFRSWLNPRAFVYRKANKIPDDLGTAVNVM HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHH QMVFGNRGDTSATGVCFTRNPATGEKELYGEFLVNAQGEDVVAGIRTPRSLAEMEEVLPE HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHH AYHDLIDTMKKMESHYRDMQDMEFTVENGKLYLLQTRNGKRTAAAALKVARDLVDEGVIT HHHHHHHHHHHHHHHHCCHHHCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC KEEALMRIEPAQLDQLLHEAIDPDHSEQPVAEGLPASPGAAVGEAVFDADVAAERGAKGE HHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC KVVLIRFETTPDDIHGVIVSQGVLTAHGGMTSHAAVVARGMGKPCVAGARGIKIDAKAAT EEEEEEEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCEEE LTIGDTVIHEGDMITLDGSTGEVFASGLKLIPPQINADFQEVLSWADEIRRLGVEANADN EEECCCEEECCCEEEEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC ATDAAKARELGAEGIGLCRTEHMFFGADRLPAMHEMITADTPEERQAAVDKILPMQQDDF CHHHHHHHHHCCCCCCCEEHHHHEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHH EGIFTAMKGLPVTVRLLDPPLHEFLPNLVEQSLKVQKMENQGADAGELDKERRLLAQVKK HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH LHEQNPMLGTRGCRLGMLYPEIPDMQARAIIRAVLSVLKKEGETVQIHIMIPLVFTPIEL HHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCH ETHRRIVQQAIDEEFESAGTKVDVKIGTMIELPRAALVADKIAEVADFFSFGTNDLTQTT HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHH LGISRDDAENGFLTEYLRTKVLKDNPFASIDQEGVGQLVAGAVEKGRKTNPELSVGVCGE CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC HGGDPDSIHFFNKTGLDYVSCSPFRVPIARFAAAQAVISQQEK CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11481430; 9168612 [H]