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The map label for this gene is deoC2

Identifier: 50843489

GI number: 50843489

Start: 2219066

End: 2219740

Strand: Direct

Name: deoC2

Synonym: PPA2045

Alternate gene names: 50843489

Gene position: 2219066-2219740 (Clockwise)

Preceding gene: 50843487

Following gene: 50843494

Centisome position: 86.67

GC content: 63.56

Gene sequence:

>675_bases
ATGTCCTCTGCCCCACTGTCTGCCACCGAGTTGGCCGGCATGATCGATCACACCCTGCTGACCCCTGAGGCCACCCACAA
CGACGTCGCCAAGCTGGTCGCCGATGCCAAAAAATATGGGACGTGGTCGGTGTGCGTATCGCCATCGATGCTGCCGTTGA
ACCTCGACATGGGTGACGTGCATCTGGCCGTCGTGTGCGGGTTTCCGTCAGGCAAGCACACCAGCGCAGTAAAGGCTGCT
GAGGCTCGTGAGGCCATCGCCGCAGGGGCCGAGGAGGTCGACATGGTGATCAACCTTGGTCTGGTAAAGGAGGGACGCTG
GGAGGACGTCACCGCCGATATCGCTGCCGTCAAGCAGGCCGTCCCGGATCCGAAGATCCTTAAGGTCATTATCGAGTCGG
CGGTGCTGACCGACGACGAGATCGTGCGGGCATGCCAGGCTGCCGAGAAGGCCGGCGCCGACTTCGTCAAGACGTCGACG
GGATTCCACCCACGTGGCGGCGCAAGCGTCGAGGCCGTCAAGGTCATGGCTGACACTGTTGGTGGACGTCTGGGCGTCAA
AGCGTCCGGCGGCATCCGCGACTACCAGACGGCATGCGCGATGGTCGAGGCCGGGGCGACGCGTCTAGGAGTTTCCTCGA
CCGCCAAGATCCTTGCCGGAGCTCCCACGGAGTGA

Upstream 100 bases:

>100_bases
GTCGAAGAGCGCAGACGCCGCCTGATGGGACTGCTGGAACAGGAGACCACTAACGACAAGCCAGTAGGCTGGAGGCACTT
ACCCAAGACAAGGAGCTGGC

Downstream 100 bases:

>100_bases
CGCCGTGCGTAGCGTTGACGCTGTCAAAGCACGGGCTGAGTCGACGACGGATTAACCTCAGCCGCGCCCTTGGCGGCAGC
CTCGCGACGTTTCCAGTTAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 2; DERA 2; Deoxyriboaldolase 2

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSSAPLSATELAGMIDHTLLTPEATHNDVAKLVADAKKYGTWSVCVSPSMLPLNLDMGDVHLAVVCGFPSGKHTSAVKAA
EAREAIAAGAEEVDMVINLGLVKEGRWEDVTADIAAVKQAVPDPKILKVIIESAVLTDDEIVRACQAAEKAGADFVKTST
GFHPRGGASVEAVKVMADTVGGRLGVKASGGIRDYQTACAMVEAGATRLGVSSTAKILAGAPTE

Sequences:

>Translated_224_residues
MSSAPLSATELAGMIDHTLLTPEATHNDVAKLVADAKKYGTWSVCVSPSMLPLNLDMGDVHLAVVCGFPSGKHTSAVKAA
EAREAIAAGAEEVDMVINLGLVKEGRWEDVTADIAAVKQAVPDPKILKVIIESAVLTDDEIVRACQAAEKAGADFVKTST
GFHPRGGASVEAVKVMADTVGGRLGVKASGGIRDYQTACAMVEAGATRLGVSSTAKILAGAPTE
>Mature_223_residues
SSAPLSATELAGMIDHTLLTPEATHNDVAKLVADAKKYGTWSVCVSPSMLPLNLDMGDVHLAVVCGFPSGKHTSAVKAAE
AREAIAAGAEEVDMVINLGLVKEGRWEDVTADIAAVKQAVPDPKILKVIIESAVLTDDEIVRACQAAEKAGADFVKTSTG
FHPRGGASVEAVKVMADTVGGRLGVKASGGIRDYQTACAMVEAGATRLGVSSTAKILAGAPTE

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=154, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790841, Length=209, Percent_Identity=31.1004784688995, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17533015, Length=177, Percent_Identity=29.3785310734463, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922098, Length=156, Percent_Identity=32.0512820512821, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC2_PROAC (Q6A655)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056716.1
- ProteinModelPortal:   Q6A655
- SMR:   Q6A655
- GeneID:   2932715
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2045
- NMPDR:   fig|267747.1.peg.1993
- HOGENOM:   HBG636421
- OMA:   CGFPSGK
- ProtClustDB:   PRK00507
- BioCyc:   PACN267747:PPA2045-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23010; Mature: 22878

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: ACT_SITE 157-157 ACT_SITE 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAPLSATELAGMIDHTLLTPEATHNDVAKLVADAKKYGTWSVCVSPSMLPLNLDMGDV
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCE
HLAVVCGFPSGKHTSAVKAAEAREAIAAGAEEVDMVINLGLVKEGRWEDVTADIAAVKQA
EEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCHHHHHHHHHHHH
VPDPKILKVIIESAVLTDDEIVRACQAAEKAGADFVKTSTGFHPRGGASVEAVKVMADTV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHC
GGRLGVKASGGIRDYQTACAMVEAGATRLGVSSTAKILAGAPTE
CCEECCCCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSAPLSATELAGMIDHTLLTPEATHNDVAKLVADAKKYGTWSVCVSPSMLPLNLDMGDV
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCE
HLAVVCGFPSGKHTSAVKAAEAREAIAAGAEEVDMVINLGLVKEGRWEDVTADIAAVKQA
EEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCHHHHHHHHHHHH
VPDPKILKVIIESAVLTDDEIVRACQAAEKAGADFVKTSTGFHPRGGASVEAVKVMADTV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHC
GGRLGVKASGGIRDYQTACAMVEAGATRLGVSSTAKILAGAPTE
CCEECCCCCCCCHHHHHHHHHHHCCCHHCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA