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The map label for this gene is yxjL [H]

Identifier: 50843473

GI number: 50843473

Start: 2201372

End: 2202046

Strand: Direct

Name: yxjL [H]

Synonym: PPA2028

Alternate gene names: 50843473

Gene position: 2201372-2202046 (Clockwise)

Preceding gene: 50843472

Following gene: 50843474

Centisome position: 85.98

GC content: 63.41

Gene sequence:

>675_bases
ATGACCGACCCGATCCGACTCCTCCTGGCCGACGACCAGCAGATGGTGCGCGCCGGGTTCCGCCTAGTCCTTGACGCCCA
GCCGGATATGTCCGTCGTCGGGGAGGCTAATGACGGAGCTGAGGCCTTACAGCTCGTCGACGAGTTGGCCCCCGATGTTG
TCCTTATGGATATCCGGATGCCTGTCCTTGATGGTTTGGGCGCCACCGAGAAGATCATGACAAGCCACCCTGAGGCCAAG
ATCCTCGTGCTGACGACCTTCGACCTTGACGAGTACGTCCACTCTGCGCTGCGAGCAGGGGCGTCCGGATTCATGCTCAA
AGACGCTGGGCCCACCGAACTACTAGCCGCCATCCGCGCTGTCCGCGACGGTGACTCTGTCGTCGCCCCGTCGGCCACTC
GCCGCCTCATAGAGAGGTTCATCCCCCGTCAGGGCGAAGGGGCTGCGACCATAACCGACCCGAAGCTCGTCGAGACTCTC
TCAGACCGGGAGCGCGAGGTGCTTACCTGCGTCGGCGAAGGACTCACGAACGCCGAGATCGCCGAACGGCTCTACCTGGC
CGAGACGACCGTCAAAACCCACATTGGCCACATCCTGTCAAAGCTGGGGCTGCGCGACCGCGTCTCCATGGTCATCACGG
CCTATGATGCCGGTCTGGTGCGTCCGGGTCGCTGA

Upstream 100 bases:

>100_bases
TGGCACCCTTGAGGTAGGGAGTCGCCCGGGCCACGGGTTCCGAGTCCGTGCCGTCATCCCTACCCGTTGATCGTCAGTTT
GAGCCCCGAAGGACCACGCC

Downstream 100 bases:

>100_bases
CCTTTCAGTTGACTACGGCGCTGCCGAAAATGGGCACATCCTCCTGCGGTAGGAGAGCCGAAACCACTCCCGGGACCGAT
GTGTGACGAGGGAAAACACC

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTDPIRLLLADDQQMVRAGFRLVLDAQPDMSVVGEANDGAEALQLVDELAPDVVLMDIRMPVLDGLGATEKIMTSHPEAK
ILVLTTFDLDEYVHSALRAGASGFMLKDAGPTELLAAIRAVRDGDSVVAPSATRRLIERFIPRQGEGAATITDPKLVETL
SDREREVLTCVGEGLTNAEIAERLYLAETTVKTHIGHILSKLGLRDRVSMVITAYDAGLVRPGR

Sequences:

>Translated_224_residues
MTDPIRLLLADDQQMVRAGFRLVLDAQPDMSVVGEANDGAEALQLVDELAPDVVLMDIRMPVLDGLGATEKIMTSHPEAK
ILVLTTFDLDEYVHSALRAGASGFMLKDAGPTELLAAIRAVRDGDSVVAPSATRRLIERFIPRQGEGAATITDPKLVETL
SDREREVLTCVGEGLTNAEIAERLYLAETTVKTHIGHILSKLGLRDRVSMVITAYDAGLVRPGR
>Mature_223_residues
TDPIRLLLADDQQMVRAGFRLVLDAQPDMSVVGEANDGAEALQLVDELAPDVVLMDIRMPVLDGLGATEKIMTSHPEAKI
LVLTTFDLDEYVHSALRAGASGFMLKDAGPTELLAAIRAVRDGDSVVAPSATRRLIERFIPRQGEGAATITDPKLVETLS
DREREVLTCVGEGLTNAEIAERLYLAETTVKTHIGHILSKLGLRDRVSMVITAYDAGLVRPGR

Specific function: Probable member of the two-component regulatory system yxjM/yxjL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=209, Percent_Identity=36.8421052631579, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1788222, Length=218, Percent_Identity=33.4862385321101, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787473, Length=193, Percent_Identity=34.7150259067358, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1790102, Length=214, Percent_Identity=31.7757009345794, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=26.4423076923077, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788712, Length=198, Percent_Identity=26.7676767676768, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082052, Length=176, Percent_Identity=32.3863636363636, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788546, Length=212, Percent_Identity=27.3584905660377, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24241; Mature: 24110

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPIRLLLADDQQMVRAGFRLVLDAQPDMSVVGEANDGAEALQLVDELAPDVVLMDIRM
CCCCEEEEEECCHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECH
PVLDGLGATEKIMTSHPEAKILVLTTFDLDEYVHSALRAGASGFMLKDAGPTELLAAIRA
HHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
VRDGDSVVAPSATRRLIERFIPRQGEGAATITDPKLVETLSDREREVLTCVGEGLTNAEI
HCCCCCEECCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHH
AERLYLAETTVKTHIGHILSKLGLRDRVSMVITAYDAGLVRPGR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCC
>Mature Secondary Structure 
TDPIRLLLADDQQMVRAGFRLVLDAQPDMSVVGEANDGAEALQLVDELAPDVVLMDIRM
CCCEEEEEECCHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECH
PVLDGLGATEKIMTSHPEAKILVLTTFDLDEYVHSALRAGASGFMLKDAGPTELLAAIRA
HHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
VRDGDSVVAPSATRRLIERFIPRQGEGAATITDPKLVETLSDREREVLTCVGEGLTNAEI
HCCCCCEECCHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHH
AERLYLAETTVKTHIGHILSKLGLRDRVSMVITAYDAGLVRPGR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]