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The map label for this gene is yxjM [H]

Identifier: 50843472

GI number: 50843472

Start: 2200064

End: 2201341

Strand: Direct

Name: yxjM [H]

Synonym: PPA2027

Alternate gene names: 50843472

Gene position: 2200064-2201341 (Clockwise)

Preceding gene: 50843467

Following gene: 50843473

Centisome position: 85.93

GC content: 63.62

Gene sequence:

>1278_bases
GTGAGCAGCGCTTCGATACCCCCACGACGCCCCCCGGGACGTTTGCGTCGTGGTTACCGATGGCTGCACGCCCACCCCAT
GATCCTCGATTCAGTAATGGCCTTCCTCGTCCTCATCGCCGCATTCGCGACGTGGGGACACGACACCAACCACAACACCG
CTTACCGCGCATGGATGGCGCTGTGGGTACTGACTGTCTGTGCGTCCTGGGTGTGGGCCCGCACCAAGCCGGAAGTGACC
GCTTCGGTGCTAGTCGCCTCACACATCCTTCAGCTAGCGGTCTACCCGTTCCCGTCACCGCAAAACACCCTAGTCCCCCT
CATCCTCTATCAGGTGTCACTGAAGACCGACCCGCCCCGGCGCAGATTCTGGCTGGCCATGTGCGTCGTCGGCCCGGTTT
CCGCCGGGGTGAGCTGGGGATTCGCCCCGACGACCTCCGAACCCATCAGCTATAACACTCACCTCATCCGCTTCTCCGTC
ATCATCATCGCGTGCATGGCCAGTTGTTTGGCAGCGTGGTTTGCCGGCAGCGCCACGAGAGACCGACGTCAAACCATGGC
AGCGTTGCGCCAACGTGCCATCGACCTGGAGCGCGAGCGCGACCAAAGCATCAGGCTAGCCACCCAGGAGGAGCGGGCCA
AGATCGCCCGGGACATGCACGACATTGTCGCCCACTCCTTGTCGGTCATCGTGGTGCAGGCAGACGGTGGCGCCTACCTG
GCTCACCATGAAGAGGCCGGCGATATCGAGACCCGACTGTCAGCCAGTGGGCAGGCCCTCGACACGATCGCTACGACGGC
CCGTCACGCCCTTGACGAGACTCGACGTCTCGTCGGTGTGCTGCGTGACAACGATGCTGGCCCGCAGCTGTCCCCCACTC
AGGGCCTTGACGACATCCCCAACCTCATCAGGGAGATGAAGGGAGCTCTCGCCATCACTCTGACGATCAAAGGCCGCTCG
GAATGTCACGAACCGTTGTCCCAAGGCGCCGAACTCGCCTGCTACCGCGTCGTCCAAGAAGCCCTCACCAATGTCCTTAA
ACACGGCGGCCCGACGGCAACCGCCCACGTCACCATCAGCCACCACCCCGATGATGTCACCTTGGACATTCTCGACGATG
GCCGCGGTACTAGCGTCACGGGTATCGAGCGCGCCGACGGGGCCGGACATGGCCTGGTGGGGATGCGAGAACGAATGTCC
GCTTGGGGTGGCACCCTTGAGGTAGGGAGTCGCCCGGGCCACGGGTTCCGAGTCCGTGCCGTCATCCCTACCCGTTGA

Upstream 100 bases:

>100_bases
AAACGCCACAACTGTCACCCGTCAGGCGGCGAGCTGAATCGTCATGAAATCCACCGACGGAAGGATGTCACACGCGTCTG
GTAGCCGTAGGGTCAGGAAA

Downstream 100 bases:

>100_bases
TCGTCAGTTTGAGCCCCGAAGGACCACGCCATGACCGACCCGATCCGACTCCTCCTGGCCGACGACCAGCAGATGGTGCG
CGCCGGGTTCCGCCTAGTCC

Product: putative two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSSASIPPRRPPGRLRRGYRWLHAHPMILDSVMAFLVLIAAFATWGHDTNHNTAYRAWMALWVLTVCASWVWARTKPEVT
ASVLVASHILQLAVYPFPSPQNTLVPLILYQVSLKTDPPRRRFWLAMCVVGPVSAGVSWGFAPTTSEPISYNTHLIRFSV
IIIACMASCLAAWFAGSATRDRRQTMAALRQRAIDLERERDQSIRLATQEERAKIARDMHDIVAHSLSVIVVQADGGAYL
AHHEEAGDIETRLSASGQALDTIATTARHALDETRRLVGVLRDNDAGPQLSPTQGLDDIPNLIREMKGALAITLTIKGRS
ECHEPLSQGAELACYRVVQEALTNVLKHGGPTATAHVTISHHPDDVTLDILDDGRGTSVTGIERADGAGHGLVGMRERMS
AWGGTLEVGSRPGHGFRVRAVIPTR

Sequences:

>Translated_425_residues
MSSASIPPRRPPGRLRRGYRWLHAHPMILDSVMAFLVLIAAFATWGHDTNHNTAYRAWMALWVLTVCASWVWARTKPEVT
ASVLVASHILQLAVYPFPSPQNTLVPLILYQVSLKTDPPRRRFWLAMCVVGPVSAGVSWGFAPTTSEPISYNTHLIRFSV
IIIACMASCLAAWFAGSATRDRRQTMAALRQRAIDLERERDQSIRLATQEERAKIARDMHDIVAHSLSVIVVQADGGAYL
AHHEEAGDIETRLSASGQALDTIATTARHALDETRRLVGVLRDNDAGPQLSPTQGLDDIPNLIREMKGALAITLTIKGRS
ECHEPLSQGAELACYRVVQEALTNVLKHGGPTATAHVTISHHPDDVTLDILDDGRGTSVTGIERADGAGHGLVGMRERMS
AWGGTLEVGSRPGHGFRVRAVIPTR
>Mature_424_residues
SSASIPPRRPPGRLRRGYRWLHAHPMILDSVMAFLVLIAAFATWGHDTNHNTAYRAWMALWVLTVCASWVWARTKPEVTA
SVLVASHILQLAVYPFPSPQNTLVPLILYQVSLKTDPPRRRFWLAMCVVGPVSAGVSWGFAPTTSEPISYNTHLIRFSVI
IIACMASCLAAWFAGSATRDRRQTMAALRQRAIDLERERDQSIRLATQEERAKIARDMHDIVAHSLSVIVVQADGGAYLA
HHEEAGDIETRLSASGQALDTIATTARHALDETRRLVGVLRDNDAGPQLSPTQGLDDIPNLIREMKGALAITLTIKGRSE
CHEPLSQGAELACYRVVQEALTNVLKHGGPTATAHVTISHHPDDVTLDILDDGRGTSVTGIERADGAGHGLVGMRERMSA
WGGTLEVGSRPGHGFRVRAVIPTR

Specific function: Probable member of the two-component regulatory system yxjM/yxjL. May activate yxjL by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=256, Percent_Identity=28.515625, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46483; Mature: 46352

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASIPPRRPPGRLRRGYRWLHAHPMILDSVMAFLVLIAAFATWGHDTNHNTAYRAWMA
CCCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LWVLTVCASWVWARTKPEVTASVLVASHILQLAVYPFPSPQNTLVPLILYQVSLKTDPPR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEEECCCCCCH
RRFWLAMCVVGPVSAGVSWGFAPTTSEPISYNTHLIRFSVIIIACMASCLAAWFAGSATR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DRRQTMAALRQRAIDLERERDQSIRLATQEERAKIARDMHDIVAHSLSVIVVQADGGAYL
HHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEE
AHHEEAGDIETRLSASGQALDTIATTARHALDETRRLVGVLRDNDAGPQLSPTQGLDDIP
EECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
NLIREMKGALAITLTIKGRSECHEPLSQGAELACYRVVQEALTNVLKHGGPTATAHVTIS
HHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
HHPDDVTLDILDDGRGTSVTGIERADGAGHGLVGMRERMSAWGGTLEVGSRPGHGFRVRA
ECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEE
VIPTR
ECCCC
>Mature Secondary Structure 
SSASIPPRRPPGRLRRGYRWLHAHPMILDSVMAFLVLIAAFATWGHDTNHNTAYRAWMA
CCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LWVLTVCASWVWARTKPEVTASVLVASHILQLAVYPFPSPQNTLVPLILYQVSLKTDPPR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEEECCCCCCH
RRFWLAMCVVGPVSAGVSWGFAPTTSEPISYNTHLIRFSVIIIACMASCLAAWFAGSATR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DRRQTMAALRQRAIDLERERDQSIRLATQEERAKIARDMHDIVAHSLSVIVVQADGGAYL
HHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEE
AHHEEAGDIETRLSASGQALDTIATTARHALDETRRLVGVLRDNDAGPQLSPTQGLDDIP
EECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
NLIREMKGALAITLTIKGRSECHEPLSQGAELACYRVVQEALTNVLKHGGPTATAHVTIS
HHHHHHCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
HHPDDVTLDILDDGRGTSVTGIERADGAGHGLVGMRERMSAWGGTLEVGSRPGHGFRVRA
ECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEE
VIPTR
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]