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The map label for this gene is nanE

Identifier: 50843444

GI number: 50843444

Start: 2169837

End: 2170526

Strand: Reverse

Name: nanE

Synonym: PPA1997

Alternate gene names: 50843444

Gene position: 2170526-2169837 (Counterclockwise)

Preceding gene: 50843445

Following gene: 50843442

Centisome position: 84.78

GC content: 65.07

Gene sequence:

>690_bases
ATGAGCGGATTCACCGACCGGATCATCGCCTCTATGGCAGGAGGGCTTGTGGTTTCCTGCCAGGCTTACCCGGGCGAGCC
GCTGCGCCACCCCGAGACGATGGCCCAGATGGCGGCTGCGGTCGAAGCCGGGGGAGCAGTGGCGGTGCGTGCCCAGGGAC
TCTCCGATGTCTCCGCCGTCAAGGGGCGCGTGAGCGTCCCAGTGGTTGGTATCTGGAAGGAGGGTGATGAGGGCATCTAC
ATCACCCCGACCCTGCGCCATGCACGCTGCGTGTCAGCTGCCGGGGCTGACGTCGTCGCCCTCGACGGCACCCGACGCGA
ACGTGCCGACGGGTTGAGCCTGGCCGAGACGATCGAACGCCTCAAGCGTGAATACGACGTCGTCGTCATGGCCGATTGTG
GCTCGGTTGATGACGGATTGTTCGCTGCTGAAGCGGGAGCCGACCTCATCGGGACGACGCTGTGCGGCTACACCGGGGAG
CGCCCCAAAACCGACGGGCCCGACTATGAGGTTATTGAAGCCCTTGTCAAGAAGCTCGATGGTGACCGTCCCGTCATCGC
TGAGGGACGTATCCACACCCCGGATCAAGCGCGCCGTGCGATGGACCTGGGAGCCCACGCCGTTGTGGTAGGGACCGCGA
TCACCCATCCGACCTCGATCACTGGATGGTTCCGTGACGCGCTGAGGTGA

Upstream 100 bases:

>100_bases
CAACCCTCACTGGGGACAACGTGGAGAGAGTTGCCGAAGTGCTGCGTCGTGTTGGCCAGCTCGCGTGAATGACAAGCATC
GATGTGAGGAGGATTCAAGT

Downstream 100 bases:

>100_bases
CCTTGCCCGTGACGAGCACCTTTCCCAGGCCGAAGCCGGGACGTTTCTCGGTATGTCACACCGGCGCGTATCCTCCGCTA
GTCAGGTCAGGCTGACTGTT

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAVKGRVSVPVVGIWKEGDEGIY
ITPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIERLKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGE
RPKTDGPDYEVIEALVKKLDGDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR

Sequences:

>Translated_229_residues
MSGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAVKGRVSVPVVGIWKEGDEGIY
ITPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIERLKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGE
RPKTDGPDYEVIEALVKKLDGDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR
>Mature_228_residues
SGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAVKGRVSVPVVGIWKEGDEGIYI
TPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIERLKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGER
PKTDGPDYEVIEALVKKLDGDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=220, Percent_Identity=43.6363636363636, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_PROAC (Q6A6A0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056671.1
- ProteinModelPortal:   Q6A6A0
- SMR:   Q6A6A0
- GeneID:   2932137
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1997
- NMPDR:   fig|267747.1.peg.1948
- HOGENOM:   HBG296941
- OMA:   AITHPAT
- ProtClustDB:   PRK01130
- BioCyc:   PACN267747:PPA1997-MONOMER
- BRENDA:   5.1.3.9
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 24057; Mature: 23925

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAV
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KGRVSVPVVGIWKEGDEGIYITPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIER
CCEECCCEEEEEECCCCCEEEECCCHHHHHHHCCCCCEEEECCCCHHHHCCCCHHHHHHH
LKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGERPKTDGPDYEVIEALVKKLD
HHHHCCEEEEECCCCCCCCEEEHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
GDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR
CCCCEEECCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SGFTDRIIASMAGGLVVSCQAYPGEPLRHPETMAQMAAAVEAGGAVAVRAQGLSDVSAV
CCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KGRVSVPVVGIWKEGDEGIYITPTLRHARCVSAAGADVVALDGTRRERADGLSLAETIER
CCEECCCEEEEEECCCCCEEEECCCHHHHHHHCCCCCEEEECCCCHHHHCCCCHHHHHHH
LKREYDVVVMADCGSVDDGLFAAEAGADLIGTTLCGYTGERPKTDGPDYEVIEALVKKLD
HHHHCCEEEEECCCCCCCCEEEHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
GDRPVIAEGRIHTPDQARRAMDLGAHAVVVGTAITHPTSITGWFRDALR
CCCCEEECCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA