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The map label for this gene is dapA [H]

Identifier: 50843445

GI number: 50843445

Start: 2170559

End: 2171479

Strand: Reverse

Name: dapA [H]

Synonym: PPA1998

Alternate gene names: 50843445

Gene position: 2171479-2170559 (Counterclockwise)

Preceding gene: 50843446

Following gene: 50843444

Centisome position: 84.81

GC content: 62.87

Gene sequence:

>921_bases
ATGACCACGAAGTTCCACGGCGTCATTCCCCCGGTCGTCACCCCACTAACCCCCAACGGTGACCTGGACGTCGCCTCCTA
CGAAAAGCTCATCAACCGCCTCATCGGGCAAGGGGTGGACGGTCTGTTCGTCCTCGGTTCCACGTCCGAGGTGGCCTTCT
TCGACGACGAGATGCGTGGACGTGTCCTGTCCGAGGCCAAGCGGATCATCGACGGTCGGGTTCCGCTGCTGGCTGGCGTC
ATTGACACAGAGACCTTGCGCGTCATCCGTCACATCGGTCAGGCCGAGGAGATTGGGGTGGACGCCGTTGTCGCCACCGC
GCCGTTCTACGCCATCACCGGGCCGACCGAGATCGAGAACCACTTCCGCGCTTTGCACGAGGCCACCGATCTGCCGTTGT
TCGTCTACGACATCCCGGTGTGTGTGCACGTCAAGGTGCCCGTCGACCTCATGATGAAGTTGGGGCGCGAGGGGGTCATC
GCAGGCTGCAAGGACTCCTCGGCTGACGACGTGTCCTTCCGCCGTCTCGCCTTGGCAAACCGTGCTGCCGGCTCCCCGCT
GTCCCTGTTCACCGGCCACGAGGTTGTCGTCGACGGGGCCTTTATGTCGGGTGCTGACGGCGTCGTGCCTGGGCTGGCTA
ACGTTGATGCGACCAGCTACGTCGCCATGTACAAGGCCTACCGTGAGGGGGATTGGGAGACGGTCCGCATTGAACAAGAC
AAGGCTGCCGAGCTGATGGAGATCGCGTTCGCACCGCAGGGTGTCGTCGGTCCGGCCGCTGGTGTGGGCGCTTTCAAGAC
GGCCATGCAGCTTCTCGGCATTATCGAAACCAACACTATGAGTGTGCCACTGCCAACCCTCACTGGGGACAACGTGGAGA
GAGTTGCCGAAGTGCTGCGTCGTGTTGGCCAGCTCGCGTGA

Upstream 100 bases:

>100_bases
AGCGGCGGTTGGCCATGATCACCTCCATTCATGACGTCATGGCGACGGCATGACACCCATCAACGACACGACATCCACGA
ACAACACGAAGGACAACACC

Downstream 100 bases:

>100_bases
ATGACAAGCATCGATGTGAGGAGGATTCAAGTATGAGCGGATTCACCGACCGGATCATCGCCTCTATGGCAGGAGGGCTT
GTGGTTTCCTGCCAGGCTTA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTTKFHGVIPPVVTPLTPNGDLDVASYEKLINRLIGQGVDGLFVLGSTSEVAFFDDEMRGRVLSEAKRIIDGRVPLLAGV
IDTETLRVIRHIGQAEEIGVDAVVATAPFYAITGPTEIENHFRALHEATDLPLFVYDIPVCVHVKVPVDLMMKLGREGVI
AGCKDSSADDVSFRRLALANRAAGSPLSLFTGHEVVVDGAFMSGADGVVPGLANVDATSYVAMYKAYREGDWETVRIEQD
KAAELMEIAFAPQGVVGPAAGVGAFKTAMQLLGIIETNTMSVPLPTLTGDNVERVAEVLRRVGQLA

Sequences:

>Translated_306_residues
MTTKFHGVIPPVVTPLTPNGDLDVASYEKLINRLIGQGVDGLFVLGSTSEVAFFDDEMRGRVLSEAKRIIDGRVPLLAGV
IDTETLRVIRHIGQAEEIGVDAVVATAPFYAITGPTEIENHFRALHEATDLPLFVYDIPVCVHVKVPVDLMMKLGREGVI
AGCKDSSADDVSFRRLALANRAAGSPLSLFTGHEVVVDGAFMSGADGVVPGLANVDATSYVAMYKAYREGDWETVRIEQD
KAAELMEIAFAPQGVVGPAAGVGAFKTAMQLLGIIETNTMSVPLPTLTGDNVERVAEVLRRVGQLA
>Mature_305_residues
TTKFHGVIPPVVTPLTPNGDLDVASYEKLINRLIGQGVDGLFVLGSTSEVAFFDDEMRGRVLSEAKRIIDGRVPLLAGVI
DTETLRVIRHIGQAEEIGVDAVVATAPFYAITGPTEIENHFRALHEATDLPLFVYDIPVCVHVKVPVDLMMKLGREGVIA
GCKDSSADDVSFRRLALANRAAGSPLSLFTGHEVVVDGAFMSGADGVVPGLANVDATSYVAMYKAYREGDWETVRIEQDK
AAELMEIAFAPQGVVGPAAGVGAFKTAMQLLGIIETNTMSVPLPTLTGDNVERVAEVLRRVGQLA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=270, Percent_Identity=24.0740740740741, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI87082415, Length=284, Percent_Identity=27.8169014084507, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789620, Length=249, Percent_Identity=29.718875502008, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786463, Length=229, Percent_Identity=29.2576419213974, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788823, Length=301, Percent_Identity=24.2524916943522, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32686; Mature: 32555

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKFHGVIPPVVTPLTPNGDLDVASYEKLINRLIGQGVDGLFVLGSTSEVAFFDDEMRG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHH
RVLSEAKRIIDGRVPLLAGVIDTETLRVIRHIGQAEEIGVDAVVATAPFYAITGPTEIEN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCEEEECCCHHHHH
HFRALHEATDLPLFVYDIPVCVHVKVPVDLMMKLGREGVIAGCKDSSADDVSFRRLALAN
HHHHHHHHCCCCEEEEECCEEEEEECCHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHH
RAAGSPLSLFTGHEVVVDGAFMSGADGVVPGLANVDATSYVAMYKAYREGDWETVRIEQD
HCCCCCEEEECCCEEEEECCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCH
KAAELMEIAFAPQGVVGPAAGVGAFKTAMQLLGIIETNTMSVPLPTLTGDNVERVAEVLR
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHH
RVGQLA
HHHCCC
>Mature Secondary Structure 
TTKFHGVIPPVVTPLTPNGDLDVASYEKLINRLIGQGVDGLFVLGSTSEVAFFDDEMRG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECHHHHH
RVLSEAKRIIDGRVPLLAGVIDTETLRVIRHIGQAEEIGVDAVVATAPFYAITGPTEIEN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCEEEECCCHHHHH
HFRALHEATDLPLFVYDIPVCVHVKVPVDLMMKLGREGVIAGCKDSSADDVSFRRLALAN
HHHHHHHHCCCCEEEEECCEEEEEECCHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHH
RAAGSPLSLFTGHEVVVDGAFMSGADGVVPGLANVDATSYVAMYKAYREGDWETVRIEQD
HCCCCCEEEECCCEEEEECCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCH
KAAELMEIAFAPQGVVGPAAGVGAFKTAMQLLGIIETNTMSVPLPTLTGDNVERVAEVLR
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHH
RVGQLA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA