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The map label for this gene is nuoA [H]

Identifier: 50843386

GI number: 50843386

Start: 2097409

End: 2097768

Strand: Reverse

Name: nuoA [H]

Synonym: PPA1936

Alternate gene names: 50843386

Gene position: 2097768-2097409 (Counterclockwise)

Preceding gene: 50843387

Following gene: 50843385

Centisome position: 81.94

GC content: 56.67

Gene sequence:

>360_bases
ATGAACGGATATGCTCCCCTCGTGGGGATGGTCATCCTCGGCGCGGTCTTCGTGCTGGCGACGATCACAGTCAACGTCCT
TCTTGCGGTAAAGCGACCCAATCGTGCCAAACACGAGATCTATGAGTGCGGTATTGAGCCGACGCCACAACCGGCAGGAG
GCGGAAAGTTCCCAGTCAAGTTCTTCGTCGTGGCAATGCTCTACATCGTGTTCGACATCGACATCATGTTCCTCTACCCG
TGGGCGGTTGACTTTAACCACCTCGGCGTCTTCGCGTTGGTGGAGATGGTGCTGTTCGTGGCGATGGTCTTCATCCCCTA
CCTCTACATCCGCCGTCGTGGCGGCTTGGATTGGACTTGA

Upstream 100 bases:

>100_bases
TTCACGTGCCGCCAAGCCTGAAGTTAGGTAACCCAAAGTACCAGGGTGTCAGATCAGAGTCGTATGGTCTGAACGAATGG
TGGTGACTAAAGGTGGTGAG

Downstream 100 bases:

>100_bases
TCTTCCCGCGCGGCCTGGGGGTCGCGCTCAGCAATATGTTGAGTGGCCTGCGAGCCACGTCACTCAACGTCTTAGAAAGA
AAGGATGCGCGAGATGGCTG

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNGYAPLVGMVILGAVFVLATITVNVLLAVKRPNRAKHEIYECGIEPTPQPAGGGKFPVKFFVVAMLYIVFDIDIMFLYP
WAVDFNHLGVFALVEMVLFVAMVFIPYLYIRRRGGLDWT

Sequences:

>Translated_119_residues
MNGYAPLVGMVILGAVFVLATITVNVLLAVKRPNRAKHEIYECGIEPTPQPAGGGKFPVKFFVVAMLYIVFDIDIMFLYP
WAVDFNHLGVFALVEMVLFVAMVFIPYLYIRRRGGLDWT
>Mature_119_residues
MNGYAPLVGMVILGAVFVLATITVNVLLAVKRPNRAKHEIYECGIEPTPQPAGGGKFPVKFFVVAMLYIVFDIDIMFLYP
WAVDFNHLGVFALVEMVLFVAMVFIPYLYIRRRGGLDWT

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13385; Mature: 13385

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGYAPLVGMVILGAVFVLATITVNVLLAVKRPNRAKHEIYECGIEPTPQPAGGGKFPVK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHH
FFVVAMLYIVFDIDIMFLYPWAVDFNHLGVFALVEMVLFVAMVFIPYLYIRRRGGLDWT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNGYAPLVGMVILGAVFVLATITVNVLLAVKRPNRAKHEIYECGIEPTPQPAGGGKFPVK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHH
FFVVAMLYIVFDIDIMFLYPWAVDFNHLGVFALVEMVLFVAMVFIPYLYIRRRGGLDWT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]