Click here to switch to the map view.

The map label for this gene is nuoN

Identifier: 50843373

GI number: 50843373

Start: 2082002

End: 2083618

Strand: Reverse

Name: nuoN

Synonym: PPA1922

Alternate gene names: 50843373

Gene position: 2083618-2082002 (Counterclockwise)

Preceding gene: 50843374

Following gene: 50843372

Centisome position: 81.38

GC content: 62.71

Gene sequence:

>1617_bases
GTGAATCCCGCCCTGTTGATTACTGCGTCTGGGCTGCCAGCGCTCCTCGACGTCGCGGCTCCGCACCTCGAGTGGGGGCC
GCTGGCGCCGGTGTTCGTCCTCATGGCAGGGGCGTGCGTGGCGGTGCTGGTGGAGGCCTTTGTTCCCCGATCGGGTCGTC
GTTCGACTCAGATCATCGTGACGGTCGCCACTCTGGTTGTTGCCATCGCCTCGACGCTAACCACTATTGCCCGTGGCACC
CGAATTGTTGCCGGGCAGGGAACTTTGGCCCCCGACGGACCGACTCTGGCTACGTGGGTCATTCTGCTAGCGACCGGTCT
TGGGACCGTGGTGCTCTTCGCTGAGCGAGTCGGCACCACCCAGACGGCTTTTGTGGCGAGCGCGTCGTCGGTGCCTGGTT
CCCCGCTGGAGGCTAAGGCCGAGCAGGAGCATCGCGAGCACACTGAGGTCTACCCGCTGCTGATGTTCGCGGCGTTGGGC
ATGATGTGTTTCGCCGCGGCTAATGACCTCATCATGATGTTCGTTGCCTTGGAGATCTTCTCTCTGCCGTTGTACCTGCT
GTGTGGGATGTCGCGGCGTCGTCGGTTGTTGTCTCAGGAAGCCGCTCTGAAGTACTTCTTGCTGGGCGCGCTGTCCTCGG
CCTTGTTCCTTTATGGCATCGTGCTGCTGTATGGATGCGCCGGCAGTTTCAAGCTTGGCGATCTAGCCGCAGCGGGCGTC
ACTCAGGTCGGCTCGTCGAAACTCATCGTCGCAGGCATGATCCTGGTGGCCGTCGGGCTGCTGTTCAAGATAGGCGCGGT
TCCGTTCGCTTCCTGGACCCCCGATGTCTACACTGGCGCTCCGACGCCGGTTAGCGGCTGGATGGCTGTCGCGACCAAAC
TCGTCGCCCTCGTCGGTCTGATGCGCGTCCTGTATGTCGGTCTGGGCGCGATGAGATGGGACTGGCAGATCGTGCTCGCC
GTCGTGGCTGTGGCCTCGATGGGTGTGGGCGCCATCGTGGGTCTCGCGCAGACCGATATGAAGCGTCTGCTGGCCTACTC
CGCTATCGCCCATGCTGGGTTCGTGCTGGTCGGTGTTGTCGGAGCCTGGACGACCCAGACCGGCATGGCCGAGGGCCAGA
CGGGTTCGGTGTCGTCGGTGCTGGTGTACATGACGGCCTATGGCTTGGCGTCGATCGGCTTCTGGCTGCTCATCCTCATG
GTGCGTCGCGCCGGTGGCGAATCCACTGAGATCGCCTCGTGGGCGGGTATTGGTCGTAGTCATCCGTGGATCGGTGTGCT
GGTCGTCATCTTTGTGCTGAGTTTCGCCGGTATCCCGTTGACGGCAGGTTTCACCGGCAAACTGGTGGTCTTCCTGGCCG
GATGGCGTGGCGGATACGCCTGGCTGGTGTTGATTGGGGTGCTGTTCTCCCTGGTGGCAGCGGCCTTCTATCTGCGCATC
ATCGTCGTGGTGTTTTTCCGGTCCGCGAAAGAGGGCGACGACCCCGTGGAGGTTGCCGAGCCCTCCATCGCCGGATGGAT
CACCCTCATCGTATGTGCGGTGTTCACCATCGTCATGGGTGTTGCCCCACAGCCGATTATTGACCTGTTCAACCAGGCGA
GCACCTTCCTGCGCTGA

Upstream 100 bases:

>100_bases
TCCCCAGGCCGATGCTGCACGCCATCGAACCAGCGGCCACGGCCACCATGACTCAGGTCCACGCCACCGATCCGGCACCC
GTCGTCAAGGAGGGTCTCAA

Downstream 100 bases:

>100_bases
GTTTGTTAATGGGGGCCGGGGCCGCTATCTGGAAGTGTTGCGACCCCGGCCTGGCTACATCTGTAGACCATGACAACGGC
ACTTCGGCAAGACGCGAGCA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MNPALLITASGLPALLDVAAPHLEWGPLAPVFVLMAGACVAVLVEAFVPRSGRRSTQIIVTVATLVVAIASTLTTIARGT
RIVAGQGTLAPDGPTLATWVILLATGLGTVVLFAERVGTTQTAFVASASSVPGSPLEAKAEQEHREHTEVYPLLMFAALG
MMCFAAANDLIMMFVALEIFSLPLYLLCGMSRRRRLLSQEAALKYFLLGALSSALFLYGIVLLYGCAGSFKLGDLAAAGV
TQVGSSKLIVAGMILVAVGLLFKIGAVPFASWTPDVYTGAPTPVSGWMAVATKLVALVGLMRVLYVGLGAMRWDWQIVLA
VVAVASMGVGAIVGLAQTDMKRLLAYSAIAHAGFVLVGVVGAWTTQTGMAEGQTGSVSSVLVYMTAYGLASIGFWLLILM
VRRAGGESTEIASWAGIGRSHPWIGVLVVIFVLSFAGIPLTAGFTGKLVVFLAGWRGGYAWLVLIGVLFSLVAAAFYLRI
IVVVFFRSAKEGDDPVEVAEPSIAGWITLIVCAVFTIVMGVAPQPIIDLFNQASTFLR

Sequences:

>Translated_538_residues
MNPALLITASGLPALLDVAAPHLEWGPLAPVFVLMAGACVAVLVEAFVPRSGRRSTQIIVTVATLVVAIASTLTTIARGT
RIVAGQGTLAPDGPTLATWVILLATGLGTVVLFAERVGTTQTAFVASASSVPGSPLEAKAEQEHREHTEVYPLLMFAALG
MMCFAAANDLIMMFVALEIFSLPLYLLCGMSRRRRLLSQEAALKYFLLGALSSALFLYGIVLLYGCAGSFKLGDLAAAGV
TQVGSSKLIVAGMILVAVGLLFKIGAVPFASWTPDVYTGAPTPVSGWMAVATKLVALVGLMRVLYVGLGAMRWDWQIVLA
VVAVASMGVGAIVGLAQTDMKRLLAYSAIAHAGFVLVGVVGAWTTQTGMAEGQTGSVSSVLVYMTAYGLASIGFWLLILM
VRRAGGESTEIASWAGIGRSHPWIGVLVVIFVLSFAGIPLTAGFTGKLVVFLAGWRGGYAWLVLIGVLFSLVAAAFYLRI
IVVVFFRSAKEGDDPVEVAEPSIAGWITLIVCAVFTIVMGVAPQPIIDLFNQASTFLR
>Mature_538_residues
MNPALLITASGLPALLDVAAPHLEWGPLAPVFVLMAGACVAVLVEAFVPRSGRRSTQIIVTVATLVVAIASTLTTIARGT
RIVAGQGTLAPDGPTLATWVILLATGLGTVVLFAERVGTTQTAFVASASSVPGSPLEAKAEQEHREHTEVYPLLMFAALG
MMCFAAANDLIMMFVALEIFSLPLYLLCGMSRRRRLLSQEAALKYFLLGALSSALFLYGIVLLYGCAGSFKLGDLAAAGV
TQVGSSKLIVAGMILVAVGLLFKIGAVPFASWTPDVYTGAPTPVSGWMAVATKLVALVGLMRVLYVGLGAMRWDWQIVLA
VVAVASMGVGAIVGLAQTDMKRLLAYSAIAHAGFVLVGVVGAWTTQTGMAEGQTGSVSSVLVYMTAYGLASIGFWLLILM
VRRAGGESTEIASWAGIGRSHPWIGVLVVIFVLSFAGIPLTAGFTGKLVVFLAGWRGGYAWLVLIGVLFSLVAAAFYLRI
IVVVFFRSAKEGDDPVEVAEPSIAGWITLIVCAVFTIVMGVAPQPIIDLFNQASTFLR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=397, Percent_Identity=35.7682619647355, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788831, Length=415, Percent_Identity=25.7831325301205, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788613, Length=380, Percent_Identity=25.5263157894737, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_PROAC (Q6A6H1)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056600.1
- GeneID:   2931182
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1922
- NMPDR:   fig|267747.1.peg.1877
- HOGENOM:   HBG747830
- OMA:   LMFFSEP
- ProtClustDB:   PRK05777
- BioCyc:   PACN267747:PPA1922-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 56416; Mature: 56416

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x130dc824)-; HASH(0x149b0a28)-; HASH(0x149b0cc8)-; HASH(0x146eb1e4)-; HASH(0x13c6b0c4)-; HASH(0x149c81ec)-; HASH(0x149f1ba0)-; HASH(0x14776aec)-; HASH(0x149f1c24)-; HASH(0x149e4f08)-; HASH(0x149f1c60)-; HASH(0x149b0c8c)-; HASH(0x1405e150)-; HASH(0x149b0a34)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPALLITASGLPALLDVAAPHLEWGPLAPVFVLMAGACVAVLVEAFVPRSGRRSTQIIV
CCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TVATLVVAIASTLTTIARGTRIVAGQGTLAPDGPTLATWVILLATGLGTVVLFAERVGTT
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTAFVASASSVPGSPLEAKAEQEHREHTEVYPLLMFAALGMMCFAAANDLIMMFVALEIF
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPLYLLCGMSRRRRLLSQEAALKYFLLGALSSALFLYGIVLLYGCAGSFKLGDLAAAGV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TQVGSSKLIVAGMILVAVGLLFKIGAVPFASWTPDVYTGAPTPVSGWMAVATKLVALVGL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MRVLYVGLGAMRWDWQIVLAVVAVASMGVGAIVGLAQTDMKRLLAYSAIAHAGFVLVGVV
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAWTTQTGMAEGQTGSVSSVLVYMTAYGLASIGFWLLILMVRRAGGESTEIASWAGIGRS
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
HPWIGVLVVIFVLSFAGIPLTAGFTGKLVVFLAGWRGGYAWLVLIGVLFSLVAAAFYLRI
CCHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IVVVFFRSAKEGDDPVEVAEPSIAGWITLIVCAVFTIVMGVAPQPIIDLFNQASTFLR
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNPALLITASGLPALLDVAAPHLEWGPLAPVFVLMAGACVAVLVEAFVPRSGRRSTQIIV
CCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TVATLVVAIASTLTTIARGTRIVAGQGTLAPDGPTLATWVILLATGLGTVVLFAERVGTT
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QTAFVASASSVPGSPLEAKAEQEHREHTEVYPLLMFAALGMMCFAAANDLIMMFVALEIF
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPLYLLCGMSRRRRLLSQEAALKYFLLGALSSALFLYGIVLLYGCAGSFKLGDLAAAGV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TQVGSSKLIVAGMILVAVGLLFKIGAVPFASWTPDVYTGAPTPVSGWMAVATKLVALVGL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MRVLYVGLGAMRWDWQIVLAVVAVASMGVGAIVGLAQTDMKRLLAYSAIAHAGFVLVGVV
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAWTTQTGMAEGQTGSVSSVLVYMTAYGLASIGFWLLILMVRRAGGESTEIASWAGIGRS
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
HPWIGVLVVIFVLSFAGIPLTAGFTGKLVVFLAGWRGGYAWLVLIGVLFSLVAAAFYLRI
CCHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IVVVFFRSAKEGDDPVEVAEPSIAGWITLIVCAVFTIVMGVAPQPIIDLFNQASTFLR
HHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA