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The map label for this gene is cobF [H]

Identifier: 50843371

GI number: 50843371

Start: 2080022

End: 2080804

Strand: Reverse

Name: cobF [H]

Synonym: PPA1920

Alternate gene names: 50843371

Gene position: 2080804-2080022 (Counterclockwise)

Preceding gene: 50843372

Following gene: 50843370

Centisome position: 81.27

GC content: 61.17

Gene sequence:

>783_bases
GTGTCCCGTCGTCTTGACCTCATCGGCATCGGCCCCGGCAACCCGGATTGGCTGACTTTGGCGGCTGTTGACGCCATCCA
GCACCTCGACGTCCTCTTTGTCGTCCTCAAGGAGCACGACGTCGATGATCTCGTCGAGTTCCGCCGTGAGGTGCTGCGTC
GTCACCGCCCCGACGCCGACTTCGATGGGTTGCACATCGTCGAGTTGCAGGATCCGCCGCGTCCATGGAAGACCGCCGAG
AACTACAAGGCGGCCGTCGCCAAGTGGCGTCGCCAGCGACTCGATCAGTGGACCCATGCCGTCGCTGACAACCTTGCCGA
CGGTGAACGCGGTGGATTTCTGGTGTGGGGTGACCCGGGCCTGTTCGAGTCCACTCTCGCCATCGTCAAGAAACTCATCG
CTGCCGTTGACGCTGACGGGGGTGTGCCGATTGAGCTCAACGTCATTCCTGGTATTTCGAGTTCGCTGTCCCTGGCGTCG
CGTCACCAGATTCCGCTCAATCGGCAAGGCCGCGCGCTGCAGATCTCGCCTGCCCGGTTGCTGGCCAACGGGATGCCGGA
GGGTGTTGACGATGTGATCGTCATGCTTGACGGGCGTCAGACTTTTAGCCTCATTGATCCCACAGATATCGATATCTACT
GGGCGGCCTACATCGGCACTCCCGACGAGATTCTCATCAGTGGGGACCTTGCTGAGGTTCGCGAGGAGATCCGGAGCGCT
CGTGCCGACGCTGAGAAGCGTTTAGGGTGGGTGTTCGATACGTATCTACTGCGTCGTCGCTGA

Upstream 100 bases:

>100_bases
GCTGCCTGACGGGGATGCCAAGCAGGCTCTTGAGGCGCTGTGCGACGAGGTGGTTTCTCGCTCGTCCTGACGCCACGTTC
GAAACTACTAAGGAGACATT

Downstream 100 bases:

>100_bases
AGTCCAGTCATTGTGACCGAGTACTCACGGTCACAATGACTGGACTTCAGCCCGCTCTCGGCGCTGGATTCGGTTGCGGC
ACAATTGTGGGCATGGATTC

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSRRLDLIGIGPGNPDWLTLAAVDAIQHLDVLFVVLKEHDVDDLVEFRREVLRRHRPDADFDGLHIVELQDPPRPWKTAE
NYKAAVAKWRRQRLDQWTHAVADNLADGERGGFLVWGDPGLFESTLAIVKKLIAAVDADGGVPIELNVIPGISSSLSLAS
RHQIPLNRQGRALQISPARLLANGMPEGVDDVIVMLDGRQTFSLIDPTDIDIYWAAYIGTPDEILISGDLAEVREEIRSA
RADAEKRLGWVFDTYLLRRR

Sequences:

>Translated_260_residues
MSRRLDLIGIGPGNPDWLTLAAVDAIQHLDVLFVVLKEHDVDDLVEFRREVLRRHRPDADFDGLHIVELQDPPRPWKTAE
NYKAAVAKWRRQRLDQWTHAVADNLADGERGGFLVWGDPGLFESTLAIVKKLIAAVDADGGVPIELNVIPGISSSLSLAS
RHQIPLNRQGRALQISPARLLANGMPEGVDDVIVMLDGRQTFSLIDPTDIDIYWAAYIGTPDEILISGDLAEVREEIRSA
RADAEKRLGWVFDTYLLRRR
>Mature_259_residues
SRRLDLIGIGPGNPDWLTLAAVDAIQHLDVLFVVLKEHDVDDLVEFRREVLRRHRPDADFDGLHIVELQDPPRPWKTAEN
YKAAVAKWRRQRLDQWTHAVADNLADGERGGFLVWGDPGLFESTLAIVKKLIAAVDADGGVPIELNVIPGISSSLSLASR
HQIPLNRQGRALQISPARLLANGMPEGVDDVIVMLDGRQTFSLIDPTDIDIYWAAYIGTPDEILISGDLAEVREEIRSAR
ADAEKRLGWVFDTYLLRRR

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 29120; Mature: 28988

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRLDLIGIGPGNPDWLTLAAVDAIQHLDVLFVVLKEHDVDDLVEFRREVLRRHRPDAD
CCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
FDGLHIVELQDPPRPWKTAENYKAAVAKWRRQRLDQWTHAVADNLADGERGGFLVWGDPG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
LFESTLAIVKKLIAAVDADGGVPIELNVIPGISSSLSLASRHQIPLNRQGRALQISPARL
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEECHHHH
LANGMPEGVDDVIVMLDGRQTFSLIDPTDIDIYWAAYIGTPDEILISGDLAEVREEIRSA
HHCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHH
RADAEKRLGWVFDTYLLRRR
HCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRRLDLIGIGPGNPDWLTLAAVDAIQHLDVLFVVLKEHDVDDLVEFRREVLRRHRPDAD
CCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
FDGLHIVELQDPPRPWKTAENYKAAVAKWRRQRLDQWTHAVADNLADGERGGFLVWGDPG
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
LFESTLAIVKKLIAAVDADGGVPIELNVIPGISSSLSLASRHQIPLNRQGRALQISPARL
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEECHHHH
LANGMPEGVDDVIVMLDGRQTFSLIDPTDIDIYWAAYIGTPDEILISGDLAEVREEIRSA
HHCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHH
RADAEKRLGWVFDTYLLRRR
HCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]