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The map label for this gene is gcp

Identifier: 50843242

GI number: 50843242

Start: 1945719

End: 1946762

Strand: Reverse

Name: gcp

Synonym: PPA1782

Alternate gene names: 50843242

Gene position: 1946762-1945719 (Counterclockwise)

Preceding gene: 50843243

Following gene: 50843241

Centisome position: 76.04

GC content: 63.41

Gene sequence:

>1044_bases
ATGTCTGAACCGCTCATTCTGGGCATCGAGTCATCGTGCGACGAGACCGGAGTTGGCATCGTTCGGGGCAATGACTTGCT
CGCCAACGAGGTCGCCTCTTCGATGGAACAGCACGTGCGCTTCGGTGGAGTCGTGCCGGAAGTGGCATCCCGAGCCCACT
TGGAGGCCATCGTCCCGGTGTTGGACAAGGCCGCCTCGACCGCCGGGGTGGACCTGTCCGAGCTCGACGGTATTGCTGTG
ACAGCCGGTCCAGGCCTGGCTGGGGCACTCGTCGTCGGCCTGTCGGCGGCCAAAGCTTTAGCAAGCTGGCTCAACAAGCC
TCTGTACGGCGTCAACCATCTGGCTGGACATGTCGCCGTCGACCTGCTTGAGCACGGTGAGCTGCCGATGCCATGTGGGG
CTCTGCTCGTCTCAGGCGGCCATACCAGCTTGCTGTGGGTAAACGACATCGCCACAGACATTATTGAGGTCGGCTCGACG
ATCGACGACGCTGCTGGCGAGGCCTACGACAAAGTGGCCCGCGTGCTTGGCCTGCCGTACCCGGGTGGGCCGGTCATCGA
CAAGGCTGCCGCCGAGGGGGACCCGACAGCGATTCGTTTCCCACGCGGACTGACGGCTCGCCACGACATGGTTAAGCATC
GCTTCGACTACTCCTTTTCCGGCCTTAAGACCGCGGTGAGTCGGTGGGTGGAGACCCAGCAGCGTGACGGAGTTGAGTTC
CGCATCGCTGACGTCGCCGCCAGTTTCCAGGAGGCCGTTGCCGACGTTCTCACTGCGAAAGCCGTCGACATGTGCCAGGA
GTATGGCCTCACTCACTTCCTCATCGGCGGCGGAGTCGCGGCGAACTCTCGTCTGCGGACTCTGCTTGCTGAGCGGATGG
CGGACGCCGGCGTTGAGTTGCGACGGCCGCGTCCGGGCCTATGCACCGACAATGGGGCCATGATCGCGGCCTTAGGTGTG
CAGGTTGTCAAGGCGGGGCTGCCTGCGTCGGCCATGGATATTTCGGCTGATTCAGGATTGCCCATCGAGACGGTGCTCGT
CTGA

Upstream 100 bases:

>100_bases
ATTTCGCAGCGACCCAACTACTACGGCGGCGGGATCGACGCCCTCGTCATGTCCGTTGATTTGCCCCGCGCCGAGACCAC
AACCCCATCCGAGGAGAACC

Downstream 100 bases:

>100_bases
GTCGGGGTAGGAATGTGAACGTGCGACCCGCTGGAGTTCGCCTACGAGATCGTGCCGCATGCCTTCGAAAGTGGACATGA
TCTGATCTTGCTGCCGGGTG

Product: putative O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSEPLILGIESSCDETGVGIVRGNDLLANEVASSMEQHVRFGGVVPEVASRAHLEAIVPVLDKAASTAGVDLSELDGIAV
TAGPGLAGALVVGLSAAKALASWLNKPLYGVNHLAGHVAVDLLEHGELPMPCGALLVSGGHTSLLWVNDIATDIIEVGST
IDDAAGEAYDKVARVLGLPYPGGPVIDKAAAEGDPTAIRFPRGLTARHDMVKHRFDYSFSGLKTAVSRWVETQQRDGVEF
RIADVAASFQEAVADVLTAKAVDMCQEYGLTHFLIGGGVAANSRLRTLLAERMADAGVELRRPRPGLCTDNGAMIAALGV
QVVKAGLPASAMDISADSGLPIETVLV

Sequences:

>Translated_347_residues
MSEPLILGIESSCDETGVGIVRGNDLLANEVASSMEQHVRFGGVVPEVASRAHLEAIVPVLDKAASTAGVDLSELDGIAV
TAGPGLAGALVVGLSAAKALASWLNKPLYGVNHLAGHVAVDLLEHGELPMPCGALLVSGGHTSLLWVNDIATDIIEVGST
IDDAAGEAYDKVARVLGLPYPGGPVIDKAAAEGDPTAIRFPRGLTARHDMVKHRFDYSFSGLKTAVSRWVETQQRDGVEF
RIADVAASFQEAVADVLTAKAVDMCQEYGLTHFLIGGGVAANSRLRTLLAERMADAGVELRRPRPGLCTDNGAMIAALGV
QVVKAGLPASAMDISADSGLPIETVLV
>Mature_346_residues
SEPLILGIESSCDETGVGIVRGNDLLANEVASSMEQHVRFGGVVPEVASRAHLEAIVPVLDKAASTAGVDLSELDGIAVT
AGPGLAGALVVGLSAAKALASWLNKPLYGVNHLAGHVAVDLLEHGELPMPCGALLVSGGHTSLLWVNDIATDIIEVGSTI
DDAAGEAYDKVARVLGLPYPGGPVIDKAAAEGDPTAIRFPRGLTARHDMVKHRFDYSFSGLKTAVSRWVETQQRDGVEFR
IADVAASFQEAVADVLTAKAVDMCQEYGLTHFLIGGGVAANSRLRTLLAERMADAGVELRRPRPGLCTDNGAMIAALGVQ
VVKAGLPASAMDISADSGLPIETVLV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=345, Percent_Identity=33.6231884057971, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=32.8267477203647, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1789445, Length=322, Percent_Identity=43.7888198757764, Blast_Score=245, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=31.0240963855422, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71995670, Length=328, Percent_Identity=31.7073170731707, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=369, Percent_Identity=29.2682926829268, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=355, Percent_Identity=25.0704225352113, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129063, Length=367, Percent_Identity=33.5149863760218, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21357207, Length=337, Percent_Identity=31.1572700296736, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PROAC (Q6A6V2)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056469.1
- ProteinModelPortal:   Q6A6V2
- SMR:   Q6A6V2
- MEROPS:   M22.001
- GeneID:   2932649
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1782
- NMPDR:   fig|267747.1.peg.1746
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   CLSK2764175
- BioCyc:   PACN267747:PPA1782-MONOMER
- BRENDA:   3.4.24.57
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35997; Mature: 35865

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLILGIESSCDETGVGIVRGNDLLANEVASSMEQHVRFGGVVPEVASRAHLEAIVPV
CCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDKAASTAGVDLSELDGIAVTAGPGLAGALVVGLSAAKALASWLNKPLYGVNHLAGHVAV
HHHHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DLLEHGELPMPCGALLVSGGHTSLLWVNDIATDIIEVGSTIDDAAGEAYDKVARVLGLPY
HHHHCCCCCCCHHHEEECCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
PGGPVIDKAAAEGDPTAIRFPRGLTARHDMVKHRFDYSFSGLKTAVSRWVETQQRDGVEF
CCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
RIADVAASFQEAVADVLTAKAVDMCQEYGLTHFLIGGGVAANSRLRTLLAERMADAGVEL
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEE
RRPRPGLCTDNGAMIAALGVQVVKAGLPASAMDISADSGLPIETVLV
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEC
>Mature Secondary Structure 
SEPLILGIESSCDETGVGIVRGNDLLANEVASSMEQHVRFGGVVPEVASRAHLEAIVPV
CCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDKAASTAGVDLSELDGIAVTAGPGLAGALVVGLSAAKALASWLNKPLYGVNHLAGHVAV
HHHHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
DLLEHGELPMPCGALLVSGGHTSLLWVNDIATDIIEVGSTIDDAAGEAYDKVARVLGLPY
HHHHCCCCCCCHHHEEECCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
PGGPVIDKAAAEGDPTAIRFPRGLTARHDMVKHRFDYSFSGLKTAVSRWVETQQRDGVEF
CCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEE
RIADVAASFQEAVADVLTAKAVDMCQEYGLTHFLIGGGVAANSRLRTLLAERMADAGVEL
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEE
RRPRPGLCTDNGAMIAALGVQVVKAGLPASAMDISADSGLPIETVLV
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA