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The map label for this gene is cdd [H]

Identifier: 50843190

GI number: 50843190

Start: 1886085

End: 1886525

Strand: Reverse

Name: cdd [H]

Synonym: PPA1730

Alternate gene names: 50843190

Gene position: 1886525-1886085 (Counterclockwise)

Preceding gene: 50843191

Following gene: 50843189

Centisome position: 73.68

GC content: 61.0

Gene sequence:

>441_bases
ATGGCACCCCTTACATCAAGGAGTGACGTGGACGTCGACTGGGACGCGTTACGCTGTCGAGCTCACGAACTGACGAAACG
AGCTTACGTGCCGTACTCCCACTTCCCAGTGGGAGCAGCCGGGCTTGCCGAGGATGGTCGCGTCGTCGTCGGATGCAATG
TGGAAAACGCTGGTTATGGCGTCACCTTGTGTGCAGAGTGCGGGCTTATCAGTGACCTCGTGGCCGGGGGTGGTGGGCAC
CTTCTCGCCTTCTGCTGCGTGGACGCTATGGGTGAGACGATCATGCCGTGTGGGCGTTGTCGCCAACTGCTGTGGGAACA
TGGTGGCCCGACGATGCTCATCGACACCCCAGCCGGGGTGCAAACGATGACCGAGGTGCTACCGCAGGCCTTCGGCGTCG
ACAACCTTGATCGTGTCGCCAACCAGCAGGAGAAGTCATGA

Upstream 100 bases:

>100_bases
AGCGCCCCGATGCCCTCGCAGTTCCTGCTCATATTGCCATACATTGCGACGATCGTCGCTGTGGCTGGTCTGGTTGGCAA
GGTGAGGGCACCTGCCTCCG

Downstream 100 bases:

>100_bases
TAGTGGCCGCAGCTGACGGGTCCTCCCTCAACAATCCGGGGCCAGCCGGCTGGGCCTGGTATATCGACGACGACACCTGG
GCTGCCGGCGGTTGGCCACG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MAPLTSRSDVDVDWDALRCRAHELTKRAYVPYSHFPVGAAGLAEDGRVVVGCNVENAGYGVTLCAECGLISDLVAGGGGH
LLAFCCVDAMGETIMPCGRCRQLLWEHGGPTMLIDTPAGVQTMTEVLPQAFGVDNLDRVANQQEKS

Sequences:

>Translated_146_residues
MAPLTSRSDVDVDWDALRCRAHELTKRAYVPYSHFPVGAAGLAEDGRVVVGCNVENAGYGVTLCAECGLISDLVAGGGGH
LLAFCCVDAMGETIMPCGRCRQLLWEHGGPTMLIDTPAGVQTMTEVLPQAFGVDNLDRVANQQEKS
>Mature_145_residues
APLTSRSDVDVDWDALRCRAHELTKRAYVPYSHFPVGAAGLAEDGRVVVGCNVENAGYGVTLCAECGLISDLVAGGGGHL
LAFCCVDAMGETIMPCGRCRQLLWEHGGPTMLIDTPAGVQTMTEVLPQAFGVDNLDRVANQQEKS

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=124, Percent_Identity=41.1290322580645, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=43.2, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=124, Percent_Identity=34.6774193548387, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=135, Percent_Identity=35.5555555555556, Blast_Score=74, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920920, Length=109, Percent_Identity=39.4495412844037, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582741, Length=89, Percent_Identity=41.5730337078652, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 15509; Mature: 15378

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLTSRSDVDVDWDALRCRAHELTKRAYVPYSHFPVGAAGLAEDGRVVVGCNVENAGYG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
VTLCAECGLISDLVAGGGGHLLAFCCVDAMGETIMPCGRCRQLLWEHGGPTMLIDTPAGV
EEEHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCH
QTMTEVLPQAFGVDNLDRVANQQEKS
HHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
APLTSRSDVDVDWDALRCRAHELTKRAYVPYSHFPVGAAGLAEDGRVVVGCNVENAGYG
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
VTLCAECGLISDLVAGGGGHLLAFCCVDAMGETIMPCGRCRQLLWEHGGPTMLIDTPAGV
EEEHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCH
QTMTEVLPQAFGVDNLDRVANQQEKS
HHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]